- The Cubs are -175 favorites vs the Phillies
- Phillies vs Cubs Over / Under today: 8 Runs
- Phillies / Cubs TV Channel: MARQ | NSP+
The Philadelphia Phillies (+145) visit Wrigley Field to take on the Chicago Cubs (-175) on April 22, 2026. First pitch is scheduled for 7:40 pm in Chicago, IL.
This season, the Phillies are 8-15 against the spread (ATS), while the Cubs are 11-12 ATS.
Phillies vs Cubs Starting Pitchers Today:
- Phillies starting pitcher: Kyle Backhus 0-0, 5.41 ERA
- Cubs starting pitcher: Matthew Boyd 1-1, 7.01 ERA
Phillies vs. Cubs Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Phillies | +1.5 -150 | O 8 -110 | +145 |
| Cubs | -1.5 +125 | U 8 -110 | -175 |
Phillies vs Cubs Prediction for Today’s Game
Based on recent trends the model predicts the Cubs will win Wednesday‘s MLB game with 55.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Phillies players for Wednesday‘s game, looking at profitable historical betting trends:
Best Phillies Player Prop Bets Today:
- Alec Bohm has hit the Total Bases Under in 21 of his last 25 games (+16.90 Units / 45% ROI)
- Alec Bohm has hit the Hits Under in 15 of his last 20 games (+12.20 Units / 40% ROI)
- Alec Bohm has hit the Hits Runs and RBIs Under in 16 of his last 20 games (+11.95 Units / 49% ROI)
- Alec Bohm has hit the Runs Under in 17 of his last 20 games (+11.90 Units / 34% ROI)
- Adolis Garcia has hit the RBIs Under in 17 of his last 20 games (+11.85 Units / 29% ROI)
And here are some favorite MLB player prop bets for Cubs players for Wednesday‘s game, looking at profitable historical betting trends:
Best Cubs Player Prop Best Bets Today:
- Nico Hoerner has hit the Home Runs Over in 3 of his last 6 games (+24.00 Units / 400% ROI)
- Alex Bregman has hit the Runs Under in 20 of his last 25 games (+13.75 Units / 36% ROI)
- Michael Busch has hit the Hits Under in 14 of his last 20 games (+12.40 Units / 52% ROI)
- Dansby Swanson has hit the Singles Under in 20 of his last 25 games (+11.75 Units / 29% ROI)
- Dansby Swanson has hit the Walks Over in 10 of his last 15 games at home (+10.80 Units / 72% ROI)
Phillies Best Bets Today:
- The Philadelphia Phillies have hit the Team Total Under in 25 of their last 35 games (+13.45 Units / 32% ROI)
- The Philadelphia Phillies have hit the 1st Five Innings (F5) Team Total Under in 31 of their last 50 away games (+9.00 Units / 15% ROI)
- The Philadelphia Phillies have hit the Game Total Over in 25 of their last 45 games (+4.05 Units / 8% ROI)
Cubs Best Bets Today:
- The Chicago Cubs have hit the Team Total Over in 25 of their last 40 games at home (+9.65 Units / 21% ROI)
- The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 25 of their last 40 games at home (+9.45 Units / 20% ROI)
- The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 29 of their last 50 games at home (+8.75 Units / 11% ROI)
- The Chicago Cubs have covered the Run Line in 14 of their last 22 games at home (+8.10 Units / 32% ROI)
- The Chicago Cubs have hit the Moneyline in their last 7 games (+7.40 Units / 88% ROI)
Phillies Against the Spread (ATS) Record
Against the spread this season, the Phillies are 4-19 against the Run Line (-16.75 Units / -64.42% ROI).
- 8-15 when betting on the Moneyline for -12.45 Units / -35.37% ROI
- 11-11 when betting on the total runs Over for -0.95 Units / -3.74% ROI
- 11-11 when betting on the total runs Under for -0.85 Units / -3.37% ROI
Cubs Against the Spread (ATS) Record
Against the spread this season, the Cubs are 11-12 against the Run Line (-0.2 Units / -0.74% ROI).
- 14-9 when betting on the Moneyline for +1.05 Units / 3.23% ROI
- 13-9 when betting on the total runs Over for +3.35 Units / 13.24% ROI
- 9-13 when betting on the total runs Under for -5.3 Units / -20.87% ROI
Cubs vs Phillies Home Run Prop Bets Today
| Yes | |
|---|---|
| Kyle Schwarber | +425 |
| Mike Busch | +475 |
| Seiya Suzuki | +525 |
| Ian Happ | +525 |
| Alex Bregman | +600 |
Cubs vs Phillies Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Alex Bregman | 0.5 -225 | 0.5 +165 |
| Seiya Suzuki | 0.5 -220 | 0.5 +160 |
| Mike Busch | 0.5 -200 | 0.5 +150 |
| Bryce Harper | 0.5 -200 | 0.5 +145 |
| Pete Crow-Armstrong | 0.5 -175 | 0.5 +130 |
Cubs vs Phillies Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Bryce Harper | 0.5 -250 | 0.5 +180 |
| Ian Happ | 0.5 -225 | 0.5 +165 |
| Edmundo Sosa | 0.5 -210 | 0.5 +150 |
| Felix Reyes | 0.5 -200 | 0.5 +145 |
| Trea Turner | 0.5 -200 | 0.5 +150 |
Phillies Keys to the Game vs. the Cubs
The Phillies were 15-45 (.250) when trailing entering the 7th inning in the 2025 season — best in MLB; League Avg: .124.
The Phillies are 29-106 (.215) when trailing entering the 7th inning since the 2024 season — best in MLB; League Avg: .134.
The Phillies are 17-59 (.224) when trailing entering the 7th inning since the 2025 season — best in MLB; League Avg: .125.
The Phillies are just 8-15 (.348) when allowing 5 or more extra base hits this season — 2nd lowest in MLB; League Avg: .525.
Cubs Keys to the Game vs. the Phillies
The Cubs are 56-7 (.889) when they’ve had 10 or more hits since the 2025 season — best in MLB; League Avg: .749.
The Cubs are 43-9 (.827) when they’ve scored in the first inning since the 2025 season — best in MLB; League Avg: .636.
The Cubs were 40-9 (.816) when they scored in the first inning in the 2025 season — best in MLB; League Avg: .636.
The Cubs were 48-6 (.889) when they had 10 or more hits in the 2025 season — best in MLB; League Avg: .743.
Phillies Hitting Stats & Trends
Phillies hitters are slugging just .280 against LHP this season — lowest in MLB.
Phillies hitters had an OPS of .812 (3,038 PA’s) at home in the 2025 season — best in MLB.
Phillies hitters had an OPS of .764 (4,220 PA’s) against RHP in the 2025 season — 5th best in MLB.
The Phillies batted just .231 when facing the starting pitcher for the 3rd time in a game in the 2025 season — 2nd lowest in MLB.
Cubs Hitting Stats & Trends
Cubs hitters have an OPS of .822 (322 PA’s) against LHP this season — 2nd best in MLB.
Cubs hitters drew walks in 5% of their PA’s against pitchers who had thrown at least 80 pitches in a game in the 2025 season — lowest in MLB.
Cubs hitters have an OBP of .292 (469 PA’s) with two-strikes this season — 2nd best in MLB.
Cubs hitters had an OPS of .761 (3,167 PA’s) on the road in the 2025 season — 3rd best in MLB.
Phillies Pitching Stats & Trends
Phillies pitchers walked 6% of batters when facing the leadoff batter in the inning in the 2025 season — best in MLB.
Phillies pitchers walked 7% of batters in the 2025 season — 2nd best in MLB.
Opponents have a groundball rate of 47% against Phillies pitchers this season — 2nd highest in MLB.
Phillies pitchers had a strikeout rate of 46% with two-strikes in the 2025 season — 2nd best in MLB.
Cubs Pitching Stats & Trends
Cubs pitchers have walked 7% of batters since the 2025 season — best in MLB.
Cubs pitchers walked 7% of batters in the 2025 season — best in MLB.
Cubs pitchers picked-off 25 runners from first base in the 2025 season — most in MLB.
Cubs pitchers had a strike rate of 66% in the 2025 season — highest in MLB.
More MLB Reading:
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