• The Phillies are -125 favorites vs the Cubs
• Phillies vs Cubs Over / Under today: 9 Runs
• Phillies / Cubs TV Channel: MARQ | NSPA

The Philadelphia Phillies (-125) visit Wrigley Field to take on the Chicago Cubs (+105) on April 23, 2026. First pitch is scheduled for 2:20 pm in Chicago, IL.

This season, the Phillies are 8-16 against the spread (ATS), while the Cubs are 12-12 ATS.

Phillies vs Cubs Starting Pitchers Today:

• Phillies starting pitcher: Cristopher Sanchez 2-2, 1.57 ERA
• Cubs starting pitcher: Edward Cabrera 2-0, 2.46 ERA

Phillies vs. Cubs Odds, Run Line, Over/Under & Moneyline

Phillies vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Phillies will win Thursday‘s MLB game with 54.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Phillies vs Cubs and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Phillies players for Thursday‘s game, looking at profitable historical betting trends:

Best Phillies Player Prop Bets Today:

• Alec Bohm has hit the Total Bases Under in 20 of his last 25 games (+13.80 Units / 37% ROI)
• Alec Bohm has hit the Hits Under in 15 of his last 20 games (+12.20 Units / 40% ROI)
• Alec Bohm has hit the Hits Runs and RBIs Under in 16 of his last 20 games (+11.65 Units / 48% ROI)
• Alec Bohm has hit the Runs Under in 17 of his last 20 games (+11.40 Units / 33% ROI)
• Rafael Marchan has hit the Home Runs Over in 2 of his last 10 games (+11.00 Units / 110% ROI)

And here are some favorite MLB player prop bets for Cubs players for Thursday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

• Nico Hoerner has hit the Home Runs Over in 3 of his last 7 games (+23.00 Units / 329% ROI)
• Seiya Suzuki has hit the Hits Over in 21 of his last 25 games (+15.20 Units / 33% ROI)
• Dansby Swanson has hit the Singles Under in 20 of his last 25 games (+11.75 Units / 29% ROI)
• Alex Bregman has hit the Runs Under in 19 of his last 25 games (+11.40 Units / 30% ROI)
• Seiya Suzuki has hit the Total Bases Over in 12 of his last 15 games at home (+10.25 Units / 54% ROI)

Phillies Best Bets Today:

• The Philadelphia Phillies have hit the Team Total Under in 33 of their last 50 away games (+13.85 Units / 24% ROI)
• The Philadelphia Phillies have hit the 1st Five Innings (F5) Team Total Under in 31 of their last 50 away games (+9.35 Units / 15% ROI)
• The Philadelphia Phillies have hit the Game Total Over in 25 of their last 45 games (+4.05 Units / 8% ROI)

Cubs Best Bets Today:

• The Chicago Cubs have hit the Team Total Over in 13 of their last 16 games (+10.10 Units / 53% ROI)
• The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 25 of their last 40 games at home (+9.45 Units / 20% ROI)
• The Chicago Cubs have covered the Run Line in 15 of their last 23 games at home (+9.25 Units / 35% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 29 of their last 50 games at home (+8.75 Units / 11% ROI)
• The Chicago Cubs have hit the Moneyline in their last 8 games (+8.40 Units / 82% ROI)

Phillies Against the Spread (ATS) Record

Against the spread this season, the Phillies are 4-20 against the Run Line (-18.1 Units / -66.18% ROI).

• 8-16 when betting on the Moneyline for -13.45 Units / -37.15% ROI
• 12-11 when betting on the total runs Over for +0.05 Units / 0.19% ROI
• 11-12 when betting on the total runs Under for -1.95 Units / -7.41% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 12-12 against the Run Line (+0.95 Units / 3.39% ROI).

• 15-9 when betting on the Moneyline for +2.05 Units / 5.97% ROI
• 14-9 when betting on the total runs Over for +4.35 Units / 16.48% ROI
• 9-14 when betting on the total runs Under for -6.4 Units / -24.15% ROI

Cubs vs Phillies Home Run Prop Bets Today

Cubs vs Phillies Total Hits Prop Bets Today

Cubs vs Phillies Strikeout Prop Bets Today

Phillies Keys to the Game vs. the Cubs

The Phillies were 15-45 (.250) when trailing entering the 7th inning in the 2025 season — best in MLB; League Avg: .124.

The Phillies are 17-60 (.221) when trailing entering the 7th inning since the 2025 season — best in MLB; League Avg: .125.

The Phillies are just 4-11 (.267) after a loss this season — 2nd lowest in MLB; League Avg: .479.

The Phillies are just 8-16 (.333) when allowing 5 or more extra base hits this season — tied for lowest in MLB; League Avg: .526.

Cubs Keys to the Game vs. the Phillies

The Cubs are 44-9 (.830) when they’ve scored in the first inning since the 2025 season — best in MLB; League Avg: .636.

The Cubs were 40-9 (.816) when they scored in the first inning in the 2025 season — best in MLB; League Avg: .636.

The Cubs are 57-7 (.891) when they’ve had 10 or more hits since the 2025 season — best in MLB; League Avg: .748.

The Cubs are 52-23 (.693) vs the bottom 10 runs allowed teams since the 2025 season Today, they face the Phillies (28th runs allowed).

Phillies Hitting Stats & Trends

Phillies hitters have an OBP of just .264 (333 PA’s) against LHP this season — lowest in MLB.

Phillies hitters are slugging just .282 against LHP this season — lowest in MLB.

Phillies hitters have an OPS of just .546 (333 PA’s) against LHP this season — lowest in MLB.

The Phillies are batting just .178 against LHP this season — lowest in MLB.

Cubs Hitting Stats & Trends

Cubs hitters have an OBP of .366 (462 PA’s) with bases empty this season — 2nd best in MLB.

Cubs hitters had an OPS of .761 (3,167 PA’s) on the road in the 2025 season — 3rd best in MLB.

Cubs hitters have an OBP of .356 (591 PA’s) at home this season — 4th best in MLB.

Cubs hitters have an OBP of .370 (327 PA’s) against LHP this season — 2nd best in MLB.

Phillies Pitching Stats & Trends

Phillies pitchers walked 6% of batters when facing the leadoff batter in the inning in the 2025 season — best in MLB.

Phillies pitchers walked 7% of batters in the 2025 season — 2nd best in MLB.

Opponents have a groundball rate of 47% against Phillies pitchers this season — tied for 4th highest in MLB.

Phillies pitchers have walked 7% of batters since the 2025 season — tied for 2nd best in MLB.

Cubs Pitching Stats & Trends

Cubs pitchers have walked 7% of batters since the 2025 season — best in MLB.

Cubs pitchers walked 7% of batters in the 2025 season — best in MLB.

Opponents had a miss rate of just 23% against Cubs pitchers in the 2025 season — 4th lowest in MLB.

Opponents have a groundball rate of just 41% against Cubs pitchers since the 2025 season — tied for 5th lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

Bet now on Phillies vs Cubs and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.