• The Pirates are -155 favorites vs the Astros
• Pirates vs Astros Over / Under today: 7.5 Runs
• Pirates / Astros TV Channel: SCHN | SNPT

The Pittsburgh Pirates (-155) visit Daikin Park to take on the Houston Astros (+125) on June 3, 2026. First pitch is scheduled for 8:10 pm in Houston, TX.

This season, the Pirates are 33-28 against the spread (ATS), while the Astros are 28-34 ATS.

Pirates vs Astros Starting Pitchers Today:

• Pirates starting pitcher: Paul Skenes 6-5, 2.91 ERA
• Astros starting pitcher: Spencer Arrighetti 7-1, 1.35 ERA

Pirates vs. Astros Odds, Run Line, Over/Under & Moneyline

Pirates vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Pirates will win Wednesday‘s MLB game with 59.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Pirates vs Astros and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Pirates players for Wednesday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

• Ryan O’Hearn has hit the Home Runs Over in 3 of his last 6 games (+19.00 Units / 317% ROI)
• Ryan O’Hearn has hit the Singles Over in 19 of his last 25 away games (+14.25 Units / 52% ROI)
• Henry Davis has hit the Total Bases Under in 19 of his last 25 games (+13.30 Units / 47% ROI)
• Brandon Lowe has hit the Hits Over in 17 of his last 20 away games (+12.25 Units / 35% ROI)
• Spencer Horwitz has hit the Hits Runs and RBIs Over in 15 of his last 20 games (+10.35 Units / 46% ROI)

And here are some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

• Jeremy Pena has hit the Home Runs Over in 3 of his last 6 games (+19.00 Units / 317% ROI)
• Cam Smith has hit the Hits Under in 16 of his last 20 games at home (+15.45 Units / 77% ROI)
• Cam Smith has hit the Singles Under in 18 of his last 20 games at home (+14.90 Units / 49% ROI)
• Cam Smith has hit the Total Bases Under in 16 of his last 20 games at home (+13.30 Units / 56% ROI)
• Cam Smith has hit the Hits Runs and RBIs Under in 16 of his last 20 games at home (+12.20 Units / 46% ROI)

Pirates Best Bets Today:

• The Pittsburgh Pirates have hit the Game Total Under in 27 of their last 45 away games (+10.80 Units / 22% ROI)
• The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 26 of their last 40 away games (+10.20 Units / 21% ROI)
• The Pittsburgh Pirates have covered the Run Line in 31 of their last 50 away games (+9.35 Units / 14% ROI)
• The Pittsburgh Pirates have hit the 1st Five Innings (F5) Moneyline in 19 of their last 40 away games (+6.35 Units / 14% ROI)
• The Pittsburgh Pirates have hit the Moneyline in 19 of their last 35 away games (+5.40 Units / 14% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the Game Total Over in 26 of their last 40 games at home (+12.40 Units / 28% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 10 of their last 11 games (+9.60 Units / 79% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Moneyline in 11 of their last 17 games (+7.45 Units / 42% ROI)
• The Houston Astros have hit the Team Total Over in 9 of their last 11 games (+7.10 Units / 56% ROI)
• The Houston Astros have covered the 1st Five Innings (F5) Run Line in 9 of their last 11 games (+6.85 Units / 49% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 31-29 against the Run Line (+3.45 Units / 4.63% ROI).

• 33-28 when betting on the Moneyline for -0.95 Units / -1.2% ROI
• 34-25 when betting on the total runs Over for +6.3 Units / 9.31% ROI
• 25-34 when betting on the total runs Under for -12 Units / -18.05% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 28-34 against the Run Line (-12.6 Units / -14.96% ROI).

• 27-35 when betting on the Moneyline for -8.75 Units / -12.34% ROI
• 34-24 when betting on the total runs Over for +6.75 Units / 9.71% ROI
• 24-34 when betting on the total runs Under for -13.1 Units / -19.58% ROI

Astros vs Pirates Home Run Prop Bets Today

Astros vs Pirates Total Hits Prop Bets Today

Astros vs Pirates Strikeout Prop Bets Today

Pirates Keys to the Game vs. the Astros

The Pirates are 28-3 (.903) when allowing 4 or fewer runs this season — 2nd best in MLB; League Avg: .720.

The Pirates are just 2-14 (.125) when allowing 10 or more hits this season — 5th lowest in MLB; League Avg: .249.

The Pirates are just 7-85 (.076) when trailing entering the 7th inning since the 2025 season — tied for 2nd lowest in MLB; League Avg: .129.

The Pirates are just 11-75 (.128) when allowing 5 or more runs since the 2025 season — 2nd lowest in MLB; League Avg: .204.

Astros Keys to the Game vs. the Pirates

The Astros are just 0-30 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .141.

The Astros are just 1-18 (.053) when allowing 10 or more hits this season — lowest in MLB; League Avg: .249.

The Astros are 26-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB; League Avg: .945.

The Astros are just 0-32 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .105.

Pirates Hitting Stats & Trends

Pirates hitters have struck out in 27% of their PA’s against LHP this season — 3rd highest in MLB.

The Pirates are batting .320 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Pirates hitters have an OBP of .374 (271 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Pirates hitters have come to the plate with runners in scoring position in 711 of their 2,405 plate appearances (30%) this season — 2nd highest in MLB.

Astros Hitting Stats & Trends

Astros hitters have an OPS of .756 (1,242 PA’s) on the road this season — 4th best in MLB.

Astros hitters are slugging .434 against LHP this season — 5th best in MLB.

29% of Astros hitters strikeouts have come on 95+ MPH fastballs this season — 4th highest in MLB.

Astros hitters have an OBP of just .304 (1,104 PA’s) at home this season — 5th lowest in MLB.

Pirates Pitching Stats & Trends

Pirates pitchers have a strikeout rate of 45% with two-strikes this season — tied for 4th best in MLB.

Pirates pitchers have walked 11% of batters when facing the leadoff batter in the inning this season — 4th highest in MLB.

Pirates pitchers have allowed 55 home runs this season — 5th fewest in MLB.

Pirates pitchers have allowed a slugging percentage of just .368 this season — 5th best in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 12% of batters this season — tied for highest in MLB.

Opponents have a groundball rate of just 39% against Astros pitchers this season — lowest in MLB.

Astros pitchers have a first-pitch strike rate of just 58% this season — 3rd lowest in MLB.

Astros pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — tied for highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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