• The Blue Jays are -170 favorites vs the Pirates
• Pirates vs Blue Jays Over / Under today: 8 Runs
• Pirates / Blue Jays TV Channel: SNPT | RSN1

The Pittsburgh Pirates (+140) visit Rogers Centre to take on the Toronto Blue Jays (-170) on May 22, 2026. First pitch is scheduled for 7:07 pm in Toronto, ON.

This season, the Pirates are 26-24 against the spread (ATS), while the Blue Jays are 25-25 ATS.

Pirates vs Blue Jays Starting Pitchers Today:

• Pirates starting pitcher: Bubba Chandler 1-5, 5.15 ERA
• Blue Jays starting pitcher: Kevin Gausman 3-3, 3.40 ERA

Pirates vs. Blue Jays Odds, Run Line, Over/Under & Moneyline

Pirates vs Blue Jays Prediction for Today’s Game

Based on recent trends the model predicts the Blue Jays will win Friday‘s MLB game with 55.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Pirates players for Friday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

• Konnor Griffin has hit the Total Bases Over in 19 of his last 25 games (+14.40 Units / 42% ROI)
• Konnor Griffin has hit the Runs Over in 15 of his last 25 games (+13.65 Units / 55% ROI)
• Konnor Griffin has hit the Hits Over in 17 of his last 20 games (+12.00 Units / 33% ROI)
• Henry Davis has hit the Singles Under in 17 of his last 20 games (+11.50 Units / 32% ROI)
• Brandon Lowe has hit the Home Runs Over in 3 of his last 7 away games (+10.10 Units / 144% ROI)

And here are some favorite MLB player prop bets for Blue Jays players for Friday‘s game, looking at profitable historical betting trends:

Best Blue Jays Player Prop Best Bets Today:

• Ernie Clement has hit the Home Runs Over in 2 of his last 7 games at home (+19.00 Units / 271% ROI)
• Jesus Sanchez has hit the Hits Runs and RBIs Over in 13 of his last 15 games at home (+11.85 Units / 66% ROI)
• Daulton Varsho has hit the Total Bases Over in 18 of his last 25 games (+11.65 Units / 36% ROI)
• Jesus Sanchez has hit the Hits Over in 13 of his last 15 games at home (+9.45 Units / 36% ROI)
• George Springer has hit the Runs Under in 18 of his last 25 games (+9.30 Units / 30% ROI)

Pirates Best Bets Today:

• The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 24 of their last 35 away games (+12.10 Units / 29% ROI)
• The Pittsburgh Pirates have hit the 1st Five Innings (F5) Moneyline in 18 of their last 35 away games (+9.05 Units / 22% ROI)
• The Pittsburgh Pirates have hit the Game Total Under in 24 of their last 40 away games (+8.90 Units / 21% ROI)
• The Pittsburgh Pirates have covered the Run Line in 28 of their last 45 away games (+8.65 Units / 14% ROI)
• The Pittsburgh Pirates have hit the Moneyline in 17 of their last 30 away games (+6.50 Units / 20% ROI)

Blue Jays Best Bets Today:

• The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 33 of their last 50 games (+16.00 Units / 27% ROI)
• The Toronto Blue Jays have covered the Run Line in 20 of their last 30 games (+10.60 Units / 27% ROI)
• The Toronto Blue Jays have hit the Team Total Under in 27 of their last 45 games (+7.35 Units / 14% ROI)
• The Toronto Blue Jays have covered the 1st Five Innings (F5) Run Line in 6 of their last 7 games (+4.90 Units / 60% ROI)
• The Toronto Blue Jays have hit the Game Total Over in 10 of their last 15 games at home (+4.50 Units / 27% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 26-23 against the Run Line (+3.9 Units / 6.3% ROI).

• 26-24 when betting on the Moneyline for -3.15 Units / -4.87% ROI
• 27-22 when betting on the total runs Over for +2.5 Units / 4.5% ROI
• 22-27 when betting on the total runs Under for -7.45 Units / -13.68% ROI

Blue Jays Against the Spread (ATS) Record

Against the spread this season, the Blue Jays are 25-25 against the Run Line (-1.65 Units / -2.58% ROI).

• 23-27 when betting on the Moneyline for -10.8 Units / -16.34% ROI
• 23-25 when betting on the total runs Over for -4.45 Units / -8.06% ROI
• 25-23 when betting on the total runs Under for +0.05 Units / 0.09% ROI

Blue Jays vs Pirates Home Run Prop Bets Today

Blue Jays vs Pirates Total Hits Prop Bets Today

Blue Jays vs Pirates Strikeout Prop Bets Today

Pirates Keys to the Game vs. the Blue Jays

The Pirates are 24-3 (.889) when allowing 4 or fewer runs this season — 2nd best in MLB; League Avg: .721.

The Pirates are just 0-18 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .055.

The Pirates are just 2-21 (.087) when allowing 5 or more runs this season — 2nd lowest in MLB; League Avg: .207.

The Pirates are just 1-12 (.077) when allowing 10 or more hits this season — 3rd lowest in MLB; League Avg: .245.

Blue Jays Keys to the Game vs. the Pirates

The Blue Jays are just 2-18 (.100) when allowing 5 or more runs this season — tied for 3rd lowest in MLB; League Avg: .207.

The Blue Jays are 16-74 (.178) when trailing entering the 8th inning since the 2025 season — best in MLB; League Avg: .094.

The Blue Jays are 84-9 (.903) when scoring 5 or more runs since the 2025 season — 2nd best in MLB; League Avg: .796.

The Blue Jays are 19-71 (.211) when trailing entering the 7th inning since the 2025 season — 2nd best in MLB; League Avg: .127.

Pirates Hitting Stats & Trends

The Pirates are batting .317 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Pirates hitters have 31 extra-base hits out of 124 total hits (just 25%) against LHP this season — lowest in MLB.

Pirates hitters have come to the plate with runners in scoring position in 599 of their 1,979 plate appearances (30%) this season — 2nd highest in MLB.

Pirates hitters have an OBP of .347 (1,411 PA’s) against RHP this season — best in MLB.

Blue Jays Hitting Stats & Trends

Blue Jays hitters have struck out in just 19% of their PA’s against RHP this season — best in MLB.

Blue Jays hitters have struck out in just 19% of their PA’s this season — 2nd best in MLB.

Blue Jays hitters have chased 35% of pitches out of the zone against RHP this season — highest in MLB.

Blue Jays hitters have an OPS of just .676 (1,868 PA’s) this season — 4th lowest in MLB.

Pirates Pitching Stats & Trends

Pirates pitchers have walked 11% of batters when facing the leadoff batter in the inning this season — 5th highest in MLB.

Opponents have a groundball batting average of just .213 against Pirates pitchers this season — 2nd best in MLB.

Pirates pitchers have allowed 44 home runs this season — tied for 5th fewest in MLB.

Pirates pitchers have allowed three-ball counts to 19% of batters they faced (372/1,919 PA’s) this season — tied for 3rd lowest in MLB.

Blue Jays Pitching Stats & Trends

Blue Jays pitchers have a strikeout rate of 24% this season — 5th best in MLB.

The Blue Jays pitchers have allowed an average Exit Velocity of just 87.7 MPH this season (1,180 balls in play) — tied for best in MLB

Blue Jays pitchers have allowed an average Exit Velocity of 87.7 MPH (1,180 batted balls) this season — tied for best in MLB.

Blue Jays pitchers have induced opposing hitters to ground into just 28 double plays in 367 opportunities (8%) this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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