• The Pirates are -135 favorites vs the Brewers
• Pirates vs Brewers Over / Under today: 7 Runs
• Pirates / Brewers TV Channel: BRTV | SNPT | ESUN

The Pittsburgh Pirates (-135) visit American Family Field to take on the Milwaukee Brewers (+110) on April 24, 2026. First pitch is scheduled for 7:40 pm in Milwaukee, WI.

This season, the Pirates are 14-11 against the spread (ATS), while the Brewers are 15-9 ATS.

Pirates vs Brewers Starting Pitchers Today:

• Pirates starting pitcher: Paul Skenes 3-1, 3.28 ERA
• Brewers starting pitcher: Brandon Woodruff 2-0, 3.47 ERA

Pirates vs. Brewers Odds, Run Line, Over/Under & Moneyline

Pirates vs Brewers Prediction for Today’s Game

Based on recent trends the model predicts the Pirates will win Friday‘s MLB game with 61.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Pirates vs Brewers and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Pirates players for Friday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

• Oneil Cruz has hit the Home Runs Over in 5 of his last 8 away games (+14.65 Units / 183% ROI)
• Oneil Cruz has hit the Hits Over in 16 of his last 20 games (+11.45 Units / 33% ROI)
• Oneil Cruz has hit the Hits Runs and RBIs Over in 12 of his last 15 away games (+9.60 Units / 57% ROI)
• Nick Gonzales has hit the Total Bases Over in 16 of his last 25 away games (+8.70 Units / 30% ROI)
• Paul Skenes has hit the Earned Runs Under in 17 of his last 25 games (+7.60 Units / 25% ROI)

And here are some favorite MLB player prop bets for Brewers players for Friday‘s game, looking at profitable historical betting trends:

Best Brewers Player Prop Best Bets Today:

• Brice Turang has hit the Hits Runs and RBIs Over in 18 of his last 25 games at home (+10.20 Units / 34% ROI)
• Brice Turang has hit the Walks Over in 14 of his last 25 games at home (+9.30 Units / 37% ROI)
• Brice Turang has hit the Hits Over in 19 of his last 25 games at home (+8.25 Units / 16% ROI)
• Brice Turang has hit the Home Runs Over in 2 of his last 10 games (+7.90 Units / 79% ROI)
• Brice Turang has hit the Runs Over in 13 of his last 20 games (+7.85 Units / 38% ROI)

Pirates Best Bets Today:

• The Pittsburgh Pirates have covered the Run Line in 23 of their last 35 games (+10.05 Units / 21% ROI)
• The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 23 of their last 35 games (+8.95 Units / 21% ROI)
• The Pittsburgh Pirates have hit the Game Total Under in 29 of their last 50 away games (+8.60 Units / 16% ROI)
• The Pittsburgh Pirates have hit the Team Total Under in 29 of their last 50 away games (+6.00 Units / 10% ROI)
• The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Over in 21 of their last 35 games (+5.75 Units / 14% ROI)

Brewers Best Bets Today:

• The Milwaukee Brewers have hit the 1st Five Innings (F5) Team Total Over in 32 of their last 50 games at home (+12.90 Units / 22% ROI)
• The Milwaukee Brewers have covered the Run Line in 15 of their last 23 games at home (+10.20 Units / 39% ROI)
• The Milwaukee Brewers have hit the Team Total Over in 28 of their last 45 games at home (+8.60 Units / 16% ROI)
• The Milwaukee Brewers have hit the Game Total Over in 29 of their last 50 games at home (+7.85 Units / 14% ROI)
• The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 27 of their last 45 games at home (+7.05 Units / 13% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 15-10 against the Run Line (+4.45 Units / 13.51% ROI).

• 14-11 when betting on the Moneyline for +1.8 Units / 5.78% ROI
• 14-11 when betting on the total runs Over for +1.75 Units / 6.34% ROI
• 11-14 when betting on the total runs Under for -4.45 Units / -16.24% ROI

Brewers Against the Spread (ATS) Record

Against the spread this season, the Brewers are 15-9 against the Run Line (+7.75 Units / 26.91% ROI).

• 13-11 when betting on the Moneyline for -1.8 Units / -5.66% ROI
• 14-10 when betting on the total runs Over for +2.8 Units / 10.45% ROI
• 10-14 when betting on the total runs Under for -5.15 Units / -19.77% ROI

Brewers vs Pirates Home Run Prop Bets Today

Brewers vs Pirates Total Hits Prop Bets Today

Brewers vs Pirates Strikeout Prop Bets Today

Pirates Keys to the Game vs. the Brewers

The Pirates were just 6-50 (.107) when they allowed 5 or more runs in the 2025 season — 2nd lowest in MLB; League Avg: .202.

The Pirates are 9-1 (.900) after a loss this season — 2nd best in MLB; League Avg: .478.

The Pirates are just 14-93 (.131) when allowing 10 or more hits since the 2024 season — 2nd lowest in MLB; League Avg: .251.

The Pirates are just 1-9 (.100) when allowing 5 or more runs this season — 2nd lowest in MLB; League Avg: .236.

Brewers Keys to the Game vs. the Pirates

The Brewers are 82-9 (.901) when scoring 5 or more runs since the 2025 season — 2nd best in MLB; League Avg: .792.

The Brewers are 2-6 (.250) when trailing entering the 8th inning this season — tied for 2nd best in MLB; League Avg: .104.

The Brewers were 97-65 (.599) in the 2025 season — best in MLB; League Avg: .500.

The Brewers were 71-7 (.910) when they scored 5 or more runs in the 2025 season — 2nd best in MLB; League Avg: .797.

Pirates Hitting Stats & Trends

Pirates hitters slugged just .333 on the road in the 2025 season — 2nd lowest in MLB.

Pirates hitters have an OPS of just .602 (2,128 PA’s) in innings 7-9 since the 2025 season — lowest in MLB.

The Pirates won only 33% of their road games in the 2025 season — tied for 2nd lowest in MLB.

Pirates hitters had an OPS of just .596 (1,843 PA’s) in innings 7-9 in the 2025 season — lowest in MLB.

Brewers Hitting Stats & Trends

Brewers hitters have an OBP of .340 (3,707 PA’s) on the road since the 2025 season — best in MLB.

Brewers hitters had a swing rate of just 45% in the 2025 season — lowest in MLB.

The Brewers batted .268 against LHP in the 2025 season — best in MLB.

Brewers hitters have chased 19% of pitches out of the zone in non-two strike counts this season — lowest in MLB.

Pirates Pitching Stats & Trends

Pirates pitchers won only 14% of games in which they allowed their opponent to score in three different innings in the 2025 season — 2nd lowest in MLB.

Pirates pitchers have walked 14% of batters when facing the leadoff batter in the inning this season — highest in MLB.

In games when their opponents scored three or more runs in an inning, the Pirates won just 13% of the time in the 2025 season — 2nd lowest in MLB.

The Pirates allowed 3.68 runs per game (298/81) at home in the 2025 season — 3rd best in MLB.

Brewers Pitching Stats & Trends

Brewers pitchers have picked-off 7 runners from first base this season — most in MLB.

Brewers pitchers have picked-off 8 runners this season — most in MLB.

Brewers pitchers have an ERA of 3.64 (1654.1 IP) since the 2025 season — tied for 2nd best in MLB.

Brewers pitchers have an ERA of 3.64 (3100.2 IP) since the 2024 season — best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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