• The Cubs are -145 favorites vs the Pirates
• Pirates vs Cubs Over / Under today: 7 Runs
• Pirates / Cubs TV Channel: MARQ | SNPT

The Pittsburgh Pirates (+120) visit Wrigley Field to take on the Chicago Cubs (-145) on September 13, 2026. First pitch is scheduled for 2:20 pm in Chicago, IL.

This season, the Pirates are 74-75 against the spread (ATS), while the Cubs are 71-76 ATS.

Pirates vs Cubs Starting Pitchers Today:

• Pirates starting pitcher: Bubba Chandler 7-9, 4.26 ERA
• Cubs starting pitcher: Matthew Boyd 8-4, 4.09 ERA

Pirates vs. Cubs Odds, Run Line, Over/Under & Moneyline

Pirates vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Sunday‘s MLB game with 54.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Pirates players for Sunday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

• Nick Gonzales has hit the Runs Under in 18 of his last 20 games (+14.50 Units / 38% ROI)
• Oneil Cruz has hit the Total Bases Over in 18 of his last 25 away games (+11.65 Units / 37% ROI)
• Jake Mangum has hit the Hits Runs and RBIs Under in 15 of his last 20 away games (+9.45 Units / 36% ROI)
• Rafael Flores has hit the Singles Over in his last 6 games (+7.60 Units / 127% ROI)
• Rafael Flores has hit the Home Runs Over in 2 of his last 6 away games (+7.40 Units / 123% ROI)

And here are some favorite MLB player prop bets for Cubs players for Sunday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

• Alex Bregman has hit the Home Runs Over in 4 of his last 8 games at home (+17.50 Units / 219% ROI)
• Michael Conforto has hit the Runs Under in 22 of his last 25 games at home (+17.40 Units / 40% ROI)
• Alex Bregman has hit the Walks Under in 21 of his last 25 games at home (+13.00 Units / 25% ROI)
• Michael Conforto has hit the Total Bases Under in 18 of his last 25 games at home (+11.50 Units / 40% ROI)
• Michael Conforto has hit the Hits Under in 17 of his last 25 games at home (+10.85 Units / 42% ROI)

Pirates Best Bets Today:

• The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Under in 14 of their last 18 games (+10.60 Units / 52% ROI)
• The Pittsburgh Pirates have hit the Game Total Under in 15 of their last 22 games (+9.55 Units / 40% ROI)
• The Pittsburgh Pirates have hit the Team Total Under in 28 of their last 45 games (+9.50 Units / 18% ROI)
• The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 9 of their last 13 games (+4.35 Units / 27% ROI)
• The Pittsburgh Pirates have hit the Moneyline in 9 of their last 13 games (+4.10 Units / 23% ROI)

Cubs Best Bets Today:

• The Chicago Cubs have hit the Game Total Over in 30 of their last 50 games (+10.45 Units / 19% ROI)
• The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 14 of their last 19 games (+9.05 Units / 41% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 8 of their last 9 games at home (+7.05 Units / 67% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 12 of their last 19 games (+7.05 Units / 27% ROI)
• The Chicago Cubs have covered the Run Line in 25 of their last 45 games (+6.90 Units / 13% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 70-75 against the Run Line (-11.15 Units / -5.91% ROI).

• 74-75 when betting on the Moneyline for -12 Units / -6.51% ROI
• 76-67 when betting on the total runs Over for +2.35 Units / 1.43% ROI
• 67-76 when betting on the total runs Under for -16.25 Units / -9.94% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 71-76 against the Run Line (-2.05 Units / -1.17% ROI).

• 83-66 when betting on the Moneyline for -0.7 Units / -0.35% ROI
• 82-64 when betting on the total runs Over for +12.4 Units / 7.55% ROI
• 64-82 when betting on the total runs Under for -25.55 Units / -15.59% ROI

Pirates Keys to the Game vs. the Cubs

The Pirates are just 6-36 (.143) when allowing 10 or more hits this season — 2nd lowest in MLB.

The Pirates are just 10-24 (.294) when their opponents score in the first inning this season — 4th lowest in MLB.

The Pirates are just 23-99 (.189) when allowing 2 or more home runs since the 2024 season — lowest in MLB.

The Pirates are just 19-54 (.260) when their opponents score in the first inning since the 2025 season — 3rd lowest in MLB.

Cubs Keys to the Game vs. the Pirates

The Cubs are 6-59 (.092) when trailing entering the 9th inning this season — 2nd best in MLB.

The Cubs are 45-6 (.882) when they’ve had 10 or more hits this season — 3rd best in MLB.

The Cubs are 30-34 (.469) when allowing 2 or more home runs this season — best in MLB.

The Cubs are 18-28 (.391) when allowing 10 or more hits this season — best in MLB.

Pirates Hitting Stats & Trends

Pirates hitters have struck out in 26% of their PA’s against LHP this season — 2nd highest in MLB.

Pirates hitters have an OBP of .347 (2,774 PA’s) at home this season — 3rd best in MLB.

Pirates hitters have an OBP of .339 (3,970 PA’s) against RHP this season — 3rd best in MLB.

The Pirates are batting .276 when facing the starting pitcher for the 3rd time in a game this season — 3rd best in MLB.

Cubs Hitting Stats & Trends

Cubs hitters have an OPS of .807 (1,570 PA’s) against LHP this season — best in MLB.

Cubs hitters have an OBP of .352 (1,570 PA’s) against LHP this season — best in MLB.

Cubs hitters are slugging .455 against LHP this season — best in MLB.

Cubs hitters have an OPS of .780 (1,862 PA’s) in innings 7-9 this season — best in MLB.

Pirates Pitching Stats & Trends

Pirates pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 3rd highest in MLB.

The Pirates have won just 23% of games in which their opponents scored first this season — 3rd lowest in MLB.

The Pirates pitchers have allowed their opponents to score first in just 44% of their games this season — 2nd lowest in MLB.

Pirates pitchers have allowed 144 home runs this season — 2nd fewest in MLB.

Cubs Pitching Stats & Trends

Opponents have a groundball batting average of just .223 against Cubs pitchers this season — best in MLB.

Opponents have a groundball batting average of just .213 against Cubs pitchers with runners on base this season — best in MLB.

The Cubs pitchers have allowed an average Exit Velocity of 89.4 MPH this season (3,438 balls in play) — 4th highest in MLB

Cubs pitchers have allowed an exit velocity of 95 MPH or greater 1,423 times this season — 4th most in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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