• The Diamondbacks are -125 favorites vs the Pirates
• Pirates vs Diamondbacks Over / Under today: 9 Runs
• Pirates / Diamondbacks TV Channel: DBTV | SNPT

The Pittsburgh Pirates (+105) visit Chase Field to take on the Arizona Diamondbacks (-125) on May 5, 2026. First pitch is scheduled for 9:40 pm in Phoenix, AZ.

This season, the Pirates are 19-16 against the spread (ATS), while the Diamondbacks are 21-12 ATS.

Pirates vs Diamondbacks Starting Pitchers Today:

• Pirates starting pitcher: Bubba Chandler 1-3, 4.97 ERA
• Diamondbacks starting pitcher: Eduardo Rodriguez 2-0, 3.03 ERA

Pirates vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

Pirates vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Diamondbacks will win Tuesday‘s MLB game with 51.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Pirates players for Tuesday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

• Ryan O’Hearn has hit the Singles Over in 16 of his last 20 away games (+13.85 Units / 67% ROI)
• Ryan O’Hearn has hit the Hits Over in 17 of his last 20 away games (+13.10 Units / 39% ROI)
• Oneil Cruz has hit the Home Runs Over in 5 of his last 10 away games (+12.65 Units / 126% ROI)
• Oneil Cruz has hit the RBIs Over in 9 of his last 15 games (+9.55 Units / 64% ROI)
• Nick Gonzales has hit the Hits Runs and RBIs Over in 17 of his last 25 games (+9.20 Units / 32% ROI)

And here are some favorite MLB player prop bets for Diamondbacks players for Tuesday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Best Bets Today:

• Ildemaro Vargas has hit the Home Runs Over in 4 of his last 10 games at home (+28.60 Units / 286% ROI)
• Ildemaro Vargas has hit the Hits Over in 21 of his last 25 games (+16.30 Units / 36% ROI)
• Alek Thomas has hit the Singles Under in 20 of his last 25 games (+13.10 Units / 34% ROI)
• Ildemaro Vargas has hit the Total Bases Over in 16 of his last 25 games (+10.00 Units / 32% ROI)
• Ildemaro Vargas has hit the Runs Over in 12 of his last 20 games (+9.35 Units / 45% ROI)

Pirates Best Bets Today:

• The Pittsburgh Pirates have covered the Run Line in 27 of their last 45 games (+9.55 Units / 16% ROI)
• The Pittsburgh Pirates have hit the Game Total Under in 24 of their last 40 away games (+8.95 Units / 21% ROI)
• The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 28 of their last 45 games (+8.20 Units / 15% ROI)
• The Pittsburgh Pirates have hit the Moneyline in 12 of their last 21 away games (+5.70 Units / 26% ROI)
• The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Over in 26 of their last 45 games (+5.40 Units / 10% ROI)

Diamondbacks Best Bets Today:

• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 19 of their last 25 games at home (+12.00 Units / 40% ROI)
• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 28 of their last 50 games at home (+11.40 Units / 17% ROI)
• The Arizona Diamondbacks have hit the Team Total Over in 31 of their last 50 games (+11.35 Units / 20% ROI)
• The Arizona Diamondbacks have hit the Game Total Over in 29 of their last 50 games (+9.45 Units / 17% ROI)
• The Arizona Diamondbacks have hit the Moneyline in 25 of their last 40 games at home (+8.50 Units / 17% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 19-15 against the Run Line (+3.95 Units / 8.8% ROI).

• 19-16 when betting on the Moneyline for -0.5 Units / -1.12% ROI
• 20-15 when betting on the total runs Over for +3.35 Units / 8.66% ROI
• 15-20 when betting on the total runs Under for -6.95 Units / -18.15% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are 21-12 against the Run Line (+4.4 Units / 9.07% ROI).

• 16-17 when betting on the Moneyline for +0.25 Units / 0.69% ROI
• 20-12 when betting on the total runs Over for +7.15 Units / 19.72% ROI
• 12-20 when betting on the total runs Under for -9.8 Units / -26.89% ROI

Diamondbacks vs Pirates Home Run Prop Bets Today

Diamondbacks vs Pirates Total Hits Prop Bets Today

Diamondbacks vs Pirates Strikeout Prop Bets Today

Pirates Keys to the Game vs. the Diamondbacks

The Pirates are just 1-92 (.011) when trailing entering the 9th inning since the 2025 season — 2nd lowest in MLB; League Avg: .046.

The Pirates are just 5-88 (.054) when trailing entering the 8th inning since the 2025 season — 3rd lowest in MLB; League Avg: .094.

The Pirates are just 1-8 (.111) when allowing 10 or more hits this season — 4th lowest in MLB; League Avg: .245.

The Pirates are just 0-12 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .057.

Diamondbacks Keys to the Game vs. the Pirates

The Diamondbacks are just 71-21 (.772) when leading entering the 7th inning since the 2025 season — 2nd lowest in MLB; League Avg: .872.

The Diamondbacks are just 79-15 (.840) when leading entering the 8th inning since the 2025 season — 2nd lowest in MLB; League Avg: .906.

The Diamondbacks are just 10-4 (.714) when leading entering the 7th inning this season — tied for 2nd lowest in MLB; League Avg: .856.

The Diamondbacks are just 82-7 (.921) when leading entering the 9th inning since the 2025 season — 3rd lowest in MLB; League Avg: .954.

Pirates Hitting Stats & Trends

Pirates hitters have an OPS of just .622 (3,619 PA’s) on the road since the 2025 season — 2nd lowest in MLB.

Pirates hitters are slugging just .358 since the 2025 season — lowest in MLB.

Pirates hitters are slugging just .362 against RHP since the 2025 season — lowest in MLB.

Pirates hitters have an OBP of just .289 (3,619 PA’s) on the road since the 2025 season — 2nd lowest in MLB.

Diamondbacks Hitting Stats & Trends

Diamondbacks hitters are slugging .580 with runners in scoring position this season — best in MLB.

The Diamondbacks are batting .280 against LHP this season — best in MLB.

Diamondbacks hitters have struck out in just 19% of their PA’s against LHP since the 2025 season — 3rd best in MLB.

Diamondbacks hitters are slugging just .275 when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB.

Pirates Pitching Stats & Trends

Pirates pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — 3rd highest in MLB.

Pirates pitchers have a strikeout rate of 46% with two-strikes this season — tied for 2nd best in MLB.

Pirates pitchers have a strikeout rate of 24% this season — 5th best in MLB.

Pirates pitchers have a strikeout rate of 26% over the last 14 days — 3rd best in MLB.

Diamondbacks Pitching Stats & Trends

Diamondbacks pitchers have an ERA of 5.16 (289.1 IP) this season — 2nd highest in MLB.

Diamondbacks pitchers have a strikeout rate of just 39% with two-strikes this season — tied for 3rd lowest in MLB.

Diamondbacks pitchers have an ERA of 7.28 (94.0 IP) over the last 14 days — highest in MLB.

Diamondbacks pitchers have a strikeout rate of just 19% with runners in scoring position this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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