Pirates vs Giants Prediction, Odds & Player Prop Bets Today – MLB, May 10

San Francisco Giants designated hitter Rafael Devers rounds the bases after hitting a solo home run during the fourth inning of a baseball game against the Colorado Rockies, Sunday, Sept. 28, 2025, in San Francisco. (AP Photo/Thien-An Truong)
(AP Photo/Thien-An Truong)
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  • The Pirates are -102 favorites vs the Giants
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The Pittsburgh Pirates (-102) visit Oracle Park to take on the San Francisco Giants (-118) on May 10, 2026. First pitch is scheduled for 4:05 pm in San Francisco, CA.

This season, the Pirates are 22-18 against the spread (ATS), while the Giants are 16-22 ATS.

Pirates vs Giants Starting Pitchers Today:

  • Pirates starting pitcher: Bubba Chandler 1-4, 4.77 ERA
  • Giants starting pitcher: Tyler Mahle 1-4, 5.00 ERA

Pirates vs. Giants Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Pirates-1.5 +165O 8 -105-102
Giants +1.5 -200U 8 -115-118

Pirates vs Giants Prediction for Today’s Game

Based on recent trends the model predicts the Giants will win Sunday‘s MLB game with 52.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Pirates players for Sunday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

  • Bryan Reynolds has hit the Walks Over in 18 of his last 25 games (+15.70 Units / 63% ROI)
  • Ryan O’Hearn has hit the Singles Over in 18 of his last 25 away games (+12.25 Units / 45% ROI)
  • Bryan Reynolds has hit the Hits Under in 15 of his last 25 games (+11.00 Units / 38% ROI)
  • Brandon Lowe has hit the Home Runs Over in 3 of his last 7 games (+10.30 Units / 147% ROI)
  • Brandon Lowe has hit the RBIs Over in 10 of his last 20 games (+7.35 Units / 37% ROI)

And here are some favorite MLB player prop bets for Giants players for Sunday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today:

  • Heliot Ramos has hit the Total Bases Over in 17 of his last 25 games (+11.55 Units / 37% ROI)
  • Rafael Devers has hit the Walks Under in 20 of his last 25 games (+10.40 Units / 23% ROI)
  • Matt Chapman has hit the Hits Runs and RBIs Under in 13 of his last 15 games (+10.30 Units / 48% ROI)
  • Rafael Devers has hit the Runs Under in 19 of his last 25 games (+9.70 Units / 23% ROI)
  • Rafael Devers has hit the Home Runs Over in 2 of his last 4 games (+8.90 Units / 222% ROI)
  • The Pittsburgh Pirates have hit the Game Total Under in 27 of their last 45 away games (+10.95 Units / 23% ROI)
  • The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 31 of their last 50 games (+9.15 Units / 16% ROI)
  • The Pittsburgh Pirates have covered the Run Line in 29 of their last 50 games (+8.55 Units / 13% ROI)
  • The Pittsburgh Pirates have hit the Moneyline in 11 of their last 18 away games (+5.20 Units / 27% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Moneyline in 15 of their last 35 away games (+4.05 Units / 10% ROI)
  • The San Francisco Giants have hit the Team Total Over in 25 of their last 40 games at home (+7.90 Units / 16% ROI)
  • The San Francisco Giants have hit the Game Total Under in 12 of their last 18 games (+5.50 Units / 28% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 24 of their last 40 games (+5.50 Units / 12% ROI)
  • The San Francisco Giants have hit the Moneyline in 8 of their last 13 games at home (+4.15 Units / 29% ROI)
  • The San Francisco Giants have covered the Run Line in 8 of their last 13 games at home (+0.90 Units / 5% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 21-18 against the Run Line (+2.95 Units / 5.82% ROI).

  • 22-18 when betting on the Moneyline for +0.4 Units / 0.8% ROI
  • 21-18 when betting on the total runs Over for +0.8 Units / 1.8% ROI
  • 18-21 when betting on the total runs Under for -4.95 Units / -11.39% ROI

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 16-22 against the Run Line (-14.45 Units / -25.53% ROI).

  • 15-24 when betting on the Moneyline for -9.1 Units / -21.46% ROI
  • 16-20 when betting on the total runs Over for -5.95 Units / -13.84% ROI
  • 20-16 when betting on the total runs Under for +2.45 Units / 5.72% ROI

Giants vs Pirates Home Run Prop Bets Today

Yes
Brandon Lowe +425
Oneil Cruz +450
Rafael Devers +500
Willy Adames +550
Marcell Ozuna +600

Giants vs Pirates Total Hits Prop Bets Today

Over Under
Jung Hoo Lee 0.5 -235 0.5 +175
Nick Gonzales 0.5 -235 0.5 +175
Ryan O'Hearn 0.5 -200 0.5 +145
Oneil Cruz 0.5 -200 0.5 +145
Brandon Lowe 0.5 -190 0.5 +140

Giants vs Pirates Strikeout Prop Bets Today

Over Under
Heliot Ramos 0.5 -235 0.5 +175
Matt Chapman 0.5 -235 0.5 +175
Joey Bart 0.5 -210 0.5 +155
Konnor Griffin 0.5 -210 0.5 +155
Marcell Ozuna 0.5 -210 0.5 +155

Pirates Keys to the Game vs. the Giants

The Pirates are 20-3 (.870) when allowing 4 or fewer runs this season — 2nd best in MLB; League Avg: .723.

The Pirates are 8-3 (.727) vs bottom 10 scoring offenses this season Today, they face the Giants (30th in runs scored).

The Pirates are just 1-9 (.100) when allowing 10 or more hits this season — 4th lowest in MLB; League Avg: .245.

The Pirates are just 0-14 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .051.

Giants Keys to the Game vs. the Pirates

The Giants are just 1-12 (.077) when allowing 10 or more hits this season — 2nd lowest in MLB; League Avg: .245.

The Giants are just 0-21 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .051.

The Giants are just 15-21 (.417) when allowing 5 or more extra base hits this season — 3rd lowest in MLB; League Avg: .532.

The Giants are just 5-22 (.185) when scoring 4 or fewer runs this season — 2nd lowest in MLB; League Avg: .277.

Pirates hitters have 23 extra-base hits out of 98 total hits (just 23%) against LHP this season — lowest in MLB.

Pirates hitters have struck out in 27% of their PA’s against LHP this season — 3rd highest in MLB.

Pirates hitters are slugging .439 at home this season — 4th best in MLB.

The Pirates are batting .283 at home this season — best in MLB.

Giants hitters have drawn walks in 5% of their PA’s against RHP this season — lowest in MLB.

Giants hitters have an OPS of just .824 (268 PA’s) with the pitcher behind in the count this season — lowest in MLB.

Giants hitters have an OBP of just .285 (1,402 PA’s) this season — lowest in MLB.

Giants hitters have drawn walks in 5% of their PA’s this season — lowest in MLB.

Pirates pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — tied for highest in MLB.

Pirates pitchers have allowed 31 home runs this season — 2nd fewest in MLB.

Opponents have a groundball batting average of .298 against Pirates pitchers with runners on base this season — 3rd highest in MLB.

Pirates pitchers have allowed a slugging percentage of just .346 this season — tied for 2nd best in MLB.

Giants pitchers have induced opposing hitters to ground into 35 double plays in 275 opportunities (13%) this season — best in MLB.

Giants pitchers have thrown at least two strikes in their first three pitches to 56% of opposing batters this season — lowest in MLB.

Opponents have a groundball rate of 47% against Giants pitchers this season — 4th highest in MLB.

Opponents have a groundball batting average of just .215 against Giants pitchers this season — tied for 2nd best in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.