• The Padres are -135 favorites vs the Pirates
• Pirates vs Padres Over / Under today: 8.5 Runs
• Pirates / Padres TV Channel: PDTV | SNPT

The Pittsburgh Pirates (+115) visit Petco Park to take on the San Diego Padres (-135) on August 26, 2026. First pitch is scheduled for 4:10 pm in San Diego, CA.

This season, the Pirates are against the spread (ATS), while the Padres are ATS.

Pirates vs Padres Starting Pitchers Today:

• Pirates starting pitcher: Bubba Chandler 6-8, 4.40 ERA
• Padres starting pitcher: Randy Vasquez 9-6, 4.21 ERA

Pirates vs. Padres Odds, Run Line, Over/Under & Moneyline

Pirates vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Wednesday‘s MLB game with 55.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Pirates vs Padres and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Pirates players for Wednesday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

• Spencer Horwitz has hit the Runs Under in 17 of his last 20 games (+13.50 Units / 40% ROI)
• Oneil Cruz has hit the Home Runs Over in 4 of his last 10 away games (+10.50 Units / 105% ROI)
• Oneil Cruz has hit the Hits Runs and RBIs Over in 14 of his last 20 games (+8.05 Units / 36% ROI)
• Nick Gonzales has hit the Total Bases Over in 15 of his last 25 away games (+7.75 Units / 27% ROI)
• Jake Mangum has hit the Singles Under in 7 of his last 8 away games (+7.35 Units / 89% ROI)

And here are some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

• Jackson Merrill has hit the Home Runs Over in 5 of his last 10 games at home (+19.00 Units / 190% ROI)
• Freddy Fermin has hit the Total Bases Over in 17 of his last 20 games (+13.65 Units / 51% ROI)
• Freddy Fermin has hit the Hits Over in 17 of his last 20 games (+12.85 Units / 47% ROI)
• Manny Machado has hit the RBIs Under in 20 of his last 25 games (+11.00 Units / 22% ROI)
• Jackson Merrill has hit the Hits Runs and RBIs Over in 18 of his last 25 games at home (+10.30 Units / 35% ROI)

Pirates Best Bets Today:

• The Pittsburgh Pirates have hit the Game Total Under in 13 of their last 18 away games (+7.55 Units / 38% ROI)
• The Pittsburgh Pirates have hit the Team Total Under in 19 of their last 30 games (+6.90 Units / 20% ROI)
• The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Over in 15 of their last 24 away games (+5.05 Units / 17% ROI)
• The Pittsburgh Pirates have covered the Run Line in 4 of their last 6 away games (+3.45 Units / 50% ROI)
• The Pittsburgh Pirates have hit the Moneyline in 7 of their last 12 games (+2.05 Units / 15% ROI)

Padres Best Bets Today:

• The San Diego Padres have covered the Run Line in 27 of their last 45 games (+13.70 Units / 24% ROI)
• The San Diego Padres have hit the Moneyline in 24 of their last 35 games at home (+11.35 Units / 26% ROI)
• The San Diego Padres have hit the Game Total Under in 29 of their last 50 games at home (+8.25 Units / 15% ROI)
• The San Diego Padres have hit the Team Total Over in 24 of their last 40 games (+6.80 Units / 15% ROI)
• The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 18 of their last 30 games at home (+4.60 Units / 13% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Padres vs Pirates Home Run Prop Bets Today

Padres vs Pirates Total Hits Prop Bets Today

Padres vs Pirates Strikeout Prop Bets Today

Pirates Keys to the Game vs. the Padres

The Pirates are just 5-34 (.128) when allowing 10 or more hits this season — 2nd lowest in MLB.

The Pirates are just 12-77 (.135) when allowing 10 or more hits since the 2025 season — lowest in MLB.

The Pirates are just 16-61 (.208) when allowing 2 or more home runs since the 2025 season — 2nd lowest in MLB.

The Pirates are just 19-52 (.268) when their opponents score in the first inning since the 2025 season — 3rd lowest in MLB.

Padres Keys to the Game vs. the Pirates

The Padres are 58-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB.

The Padres are 55-1 (.982) when leading entering the 8th inning this season — best in MLB.

The Padres are 50-7 (.877) when scoring 5 or more runs this season — 3rd best in MLB.

The Padres are 22-16 (.579) vs the top 10 runs allowed teams this season Today, they face Pirates (23rd fewest runs allowed).

Pirates Hitting Stats & Trends

Pirates hitters have an OBP of .348 (2,548 PA’s) at home this season — best in MLB.

Pirates hitters have struck out in 26% of their PA’s against LHP this season — tied for highest in MLB.

Pirates hitters have an OPS of .762 (3,589 PA’s) against RHP this season — 2nd best in MLB.

Pirates hitters have an OPS of .784 (2,548 PA’s) at home this season — 2nd best in MLB.

Padres Hitting Stats & Trends

Padres hitters have an OPS of just .682 (2,473 PA’s) at home this season — 3rd lowest in MLB.

Padres hitters have an OPS of .753 (1,591 PA’s) in innings 7-9 this season — 3rd best in MLB.

The Padres are batting .365 on the first pitch of at-bats this season — 2nd best in MLB.

The Padres are batting just .233 at home this season — tied for 4th lowest in MLB.

Pirates Pitching Stats & Trends

Pirates pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 2nd highest in MLB.

The Pirates pitchers have allowed division opponents to score first in just 40% of their games this season — 5th lowest in MLB.

Pirates pitchers have a strikeout rate of 24% this season — 5th best in MLB.

The Pirates have won just 18% of road games in which their opponents scored first this season — 5th lowest in MLB.

Padres Pitching Stats & Trends

Padres pitchers have a strikeout rate of 28% in close and late situations this season — 2nd best in MLB.

Padres pitchers have an ERA of 3.48 (624.0 IP) at home this season — 4th best in MLB.

Padres pitchers have allowed innings of 3+ runs in 4% of innings played this season — tied for 2nd lowest in MLB.

Opponents have a groundball batting average of .264 against Padres pitchers this season — tied for 4th highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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