• The Pirates are -110 favorites vs the Tigers
• Pirates vs Tigers Over / Under today: 8 Runs
• Pirates / Tigers TV Channel: DSN | SNPT

The Pittsburgh Pirates (-110) visit Comerica Park to take on the Detroit Tigers (-110) on September 25, 2026. First pitch is scheduled for 6:40 pm in Detroit, MI.

This season, the Pirates are 81-78 against the spread (ATS), while the Tigers are 75-78 ATS.

Pirates vs Tigers Starting Pitchers Today:

• Pirates starting pitcher: Bubba Chandler 8-9, 4.35 ERA
• Tigers starting pitcher: Jackson Jobe 2-3, 3.95 ERA

Pirates vs. Tigers Odds, Run Line, Over/Under & Moneyline

Pirates vs Tigers Prediction for Today’s Game

Based on recent trends the model predicts the Tigers will win Friday‘s MLB game with 53.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Pirates players for Friday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

• Brandon Lowe has hit the Home Runs Over in 5 of his last 9 games (+19.10 Units / 212% ROI)
• Spencer Horwitz has hit the Runs Under in 17 of his last 20 away games (+13.05 Units / 35% ROI)
• Oneil Cruz has hit the Total Bases Over in 18 of his last 25 away games (+11.30 Units / 35% ROI)
• Brandon Lowe has hit the Hits Over in 17 of his last 20 games (+10.85 Units / 28% ROI)
• Oneil Cruz has hit the Singles Over in 13 of his last 20 games (+9.40 Units / 47% ROI)

And here are some favorite MLB player prop bets for Tigers players for Friday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Best Bets Today:

• Ben Malgeri has hit the Home Runs Over in 3 of his last 8 games at home (+21.50 Units / 269% ROI)
• Dillon Dingler has hit the Hits Runs and RBIs Under in 20 of his last 25 games (+14.45 Units / 47% ROI)
• Dillon Dingler has hit the Runs Under in 21 of his last 25 games (+14.15 Units / 30% ROI)
• Riley Greene has hit the Hits Under in 15 of his last 25 games at home (+12.55 Units / 44% ROI)
• Dillon Dingler has hit the Total Bases Under in 16 of his last 20 games at home (+10.40 Units / 34% ROI)

Pirates Best Bets Today:

• The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Under in 26 of their last 40 games (+11.75 Units / 25% ROI)
• The Pittsburgh Pirates have hit the Game Total Under in 21 of their last 35 games (+8.95 Units / 23% ROI)
• The Pittsburgh Pirates have hit the Moneyline in 16 of their last 23 games (+8.35 Units / 27% ROI)
• The Pittsburgh Pirates have covered the Run Line in 11 of their last 15 games (+7.90 Units / 38% ROI)
• The Pittsburgh Pirates have hit the Team Total Under in 29 of their last 50 games (+6.45 Units / 11% ROI)

Tigers Best Bets Today:

• The Detroit Tigers have hit the 1st Five Innings (F5) Moneyline in 26 of their last 45 games at home (+16.85 Units / 25% ROI)
• The Detroit Tigers have hit the Game Total Under in 26 of their last 45 games at home (+8.30 Units / 17% ROI)
• The Detroit Tigers have covered the 1st Five Innings (F5) Run Line in 26 of their last 45 games at home (+5.95 Units / 11% ROI)
• The Detroit Tigers have covered the Run Line in 13 of their last 21 games (+5.55 Units / 19% ROI)
• The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Over in 15 of their last 25 games at home (+4.90 Units / 17% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 77-78 against the Run Line (-6.65 Units / -3.29% ROI).

• 81-78 when betting on the Moneyline for -7.75 Units / -3.93% ROI
• 80-72 when betting on the total runs Over for +0.9 Units / 0.51% ROI
• 72-80 when betting on the total runs Under for -15.65 Units / -8.96% ROI

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 75-78 against the Run Line (-6.65 Units / -3.28% ROI).

• 74-85 when betting on the Moneyline for -23.3 Units / -11.85% ROI
• 69-82 when betting on the total runs Over for -20.95 Units / -11.96% ROI
• 82-69 when betting on the total runs Under for +6.4 Units / 3.66% ROI

Pirates Keys to the Game vs. the Tigers

The Pirates are just 7-38 (.156) when allowing 10 or more hits this season — 4th lowest in MLB.

The Pirates are just 21-125 (.144) when allowing 10 or more hits since the 2024 season — 2nd lowest in MLB.

The Pirates are just 3-146 (.020) when trailing entering the 9th inning since the 2025 season — lowest in MLB.

The Pirates are just 14-81 (.147) when allowing 10 or more hits since the 2025 season — lowest in MLB.

Tigers Keys to the Game vs. the Pirates

The Tigers are just 64-42 (.604) when allowing 4 or fewer runs this season — lowest in MLB.

The Tigers are just 3-12 (.200) when tied entering the 7th inning this season — lowest in MLB.

The Tigers are just 4-10 (.286) when tied entering the 8th inning this season — tied for 2nd lowest in MLB.

The Tigers are just 60-18 (.769) when leading entering the 7th inning this season — tied for 2nd lowest in MLB.

Pirates Hitting Stats & Trends

Pirates hitters have an OBP of .346 (3,105 PA’s) at home this season — 3rd best in MLB.

Pirates hitters have struck out in 25% of their PA’s against LHP this season — tied for 2nd highest in MLB.

Pirates hitters have 130 extra-base hits out of 437 total hits (just 30%) against LHP this season — 3rd lowest in MLB.

Pirates hitters have an OBP of .258 (3,343 PA’s) with two-strikes this season — tied for 4th best in MLB.

Tigers Hitting Stats & Trends

Tigers hitters have chased 26% of pitches out of the zone against LHP this season — lowest in MLB.

Tigers hitters have been successful in just 60% of their sacrifice bunt attempts this season — lowest in MLB.

Tigers hitters have drawn walks in 10% of their PA’s against LHP this season — 3rd best in MLB.

The Tigers are batting just .134 on pitches out of the zone this season — 3rd lowest in MLB.

Pirates Pitching Stats & Trends

Pirates pitchers have a strikeout rate of 24% this season — tied for 5th best in MLB.

Pirates pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 4th highest in MLB.

The Pirates have won just 27% of games in which their opponents scored first this season — 4th lowest in MLB.

The Pirates pitchers have allowed their opponents to score first in just 45% of their games this season — tied for 3rd lowest in MLB.

Tigers Pitching Stats & Trends

Opponents have a groundball rate of 45% against Tigers pitchers this season — 3rd highest in MLB.

Tigers pitchers have an ERA of 3.30 (708.1 IP) at home this season — 2nd best in MLB.

Tigers pitchers have induced opposing hitters to ground into 119 double plays in 1,090 opportunities (11%) this season — tied for 3rd best in MLB.

The Tigers have allowed 3.71 runs per game (289/78) at home this season — 3rd best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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