• The Pirates are -110 favorites vs the White Sox
• Pirates vs White Sox Over / Under today: 7.5 Runs
• Pirates / White Sox TV Channel: CHSN | SNPT

The Pittsburgh Pirates (-110) visit Rate Field to take on the Chicago White Sox (-110) on September 10, 2026. First pitch is scheduled for 7:40 pm in Chicago, IL.

This season, the Pirates are 73-73 against the spread (ATS), while the White Sox are 81-61 ATS.

Pirates vs White Sox Starting Pitchers Today:

• Pirates starting pitcher: Jared Jones 3-6, 4.47 ERA
• White Sox starting pitcher: Hagen Smith 3-1, 0.56 ERA

Pirates vs. White Sox Odds, Run Line, Over/Under & Moneyline

Pirates vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the White Sox will win Thursday‘s MLB game with 54.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Pirates players for Thursday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

• Spencer Horwitz has hit the Runs Under in 20 of his last 25 games (+13.05 Units / 30% ROI)
• Jared Triolo has hit the Home Runs Over in 2 of his last 9 away games (+13.00 Units / 144% ROI)
• Esmerlyn Valdez has hit the Walks Over in 12 of his last 20 away games (+9.95 Units / 49% ROI)
• Esmerlyn Valdez has hit the Singles Under in 20 of his last 25 away games (+9.25 Units / 19% ROI)
• Oneil Cruz has hit the Total Bases Over in 17 of his last 25 away games (+8.95 Units / 28% ROI)

And here are some favorite MLB player prop bets for White Sox players for Thursday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

• Tristan Peters has hit the Home Runs Over in 5 of his last 10 games at home (+40.00 Units / 400% ROI)
• Randal Grichuk has hit the Total Bases Over in 13 of his last 15 games (+12.60 Units / 66% ROI)
• Randal Grichuk has hit the Hits Over in 14 of his last 15 games (+12.20 Units / 49% ROI)
• Munetaka Murakami has hit the Hits Runs and RBIs Under in 16 of his last 20 games (+10.85 Units / 43% ROI)
• Braden Montgomery has hit the Runs Over in 12 of his last 20 games at home (+10.75 Units / 54% ROI)

Pirates Best Bets Today:

• The Pittsburgh Pirates have hit the Game Total Under in 13 of their last 19 games (+8.65 Units / 42% ROI)
• The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Under in 11 of their last 15 games (+7.55 Units / 44% ROI)
• The Pittsburgh Pirates have hit the Team Total Under in 27 of their last 45 games (+7.55 Units / 15% ROI)
• The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 8 of their last 10 games (+5.70 Units / 47% ROI)
• The Pittsburgh Pirates have hit the Moneyline in 8 of their last 10 games (+5.10 Units / 35% ROI)

White Sox Best Bets Today:

• The Chicago White Sox have covered the Run Line in 29 of their last 50 games at home (+9.30 Units / 14% ROI)
• The Chicago White Sox have hit the Moneyline in 30 of their last 50 games at home (+8.40 Units / 14% ROI)
• The Chicago White Sox have hit the Game Total Over in 29 of their last 50 games at home (+6.65 Units / 12% ROI)
• The Chicago White Sox have hit the Team Total Under in 8 of their last 11 games (+4.60 Units / 36% ROI)
• The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 23 of their last 40 games at home (+3.55 Units / 7% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 68-74 against the Run Line (-12.55 Units / -6.8% ROI).

• 73-73 when betting on the Moneyline for -11 Units / -6.07% ROI
• 75-65 when betting on the total runs Over for +3.55 Units / 2.21% ROI
• 65-75 when betting on the total runs Under for -17.15 Units / -10.7% ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 81-61 against the Run Line (+5.75 Units / 2.81% ROI).

• 75-70 when betting on the Moneyline for +10.9 Units / 6.91% ROI
• 81-62 when betting on the total runs Over for +12.75 Units / 8.01% ROI
• 62-81 when betting on the total runs Under for -27.4 Units / -17.15% ROI

Pirates Keys to the Game vs. the White Sox

The Pirates are just 6-35 (.146) when allowing 10 or more hits this season — 2nd lowest in MLB.

The Pirates are just 23-98 (.190) when allowing 2 or more home runs since the 2024 season — lowest in MLB.

The Pirates were just 10-32 (.238) when their opponents score in the first inning in the 2024 season — 3rd lowest in MLB; League Avg: .359.

The Pirates are just 20-122 (.141) when allowing 10 or more hits since the 2024 season — 2nd lowest in MLB.

White Sox Keys to the Game vs. the Pirates

The White Sox are 14-5 (.737) when tied entering the 7th inning this season — 2nd best in MLB.

The White Sox are just 29-14 (.674) when they’ve had 10 or more hits this season — 3rd lowest in MLB.

The White Sox are just 148-102 (.592) when allowing 4 or fewer runs since the 2024 season — lowest in MLB.

The White Sox were just 35-12 (.745) when leading entering the 8th inning in the 2024 season — lowest in MLB; League Avg: .899.

Pirates Hitting Stats & Trends

Pirates hitters have an OBP of .340 (3,902 PA’s) against RHP this season — 3rd best in MLB.

Pirates hitters have an OBP of .347 (2,774 PA’s) at home this season — 2nd best in MLB.

Pirates hitters have an OPS of .756 (3,902 PA’s) against RHP this season — 3rd best in MLB.

Pirates hitters have come to the plate with runners in scoring position in 1,556 of their 5,666 plate appearances (28%) this season — 3rd highest in MLB.

White Sox Hitting Stats & Trends

White Sox hitters have 128 extra-base hits out of 325 total hits (39%) against LHP this season — best in MLB.

White Sox hitters have struck out in 25% of their PA’s against LHP this season — tied for 4th highest in MLB.

White Sox hitters have 67 extra-base hits out of 139 total hits (48%) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

White Sox hitters have grounded into 66 double plays in 1,039 opportunities (6%) this season — best in MLB.

Pirates Pitching Stats & Trends

Pirates pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — tied for 3rd highest in MLB.

The Pirates pitchers have allowed their opponents to score first in just 44% of their games this season — 2nd lowest in MLB.

Pirates pitchers have an ERA of 4.40 (660.0 IP) at home this season — tied for 4th highest in MLB.

The softest ball hit off of the Pirates pitchers this season was just 16.7 MPH — tied for 5th best in MLB

White Sox Pitching Stats & Trends

Opponents have a groundball rate of just 40% against White Sox pitchers this season — 3rd lowest in MLB.

White Sox pitchers have an ERA of 3.20 (374.1 IP) against division opponents this season — 2nd best in MLB.

The longest HR allowed by the White Sox pitchers this season traveled 460.0 feet — — tied for 3rd longest in MLB

White Sox pitchers have allowed an OBP of .336 (1,293 PA’s) when facing the leadoff batter in the inning this season — 5th highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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