Rays vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Apr 27

Cleveland Guardians' Jose Ramirez celebrates after hitting a double during the fourth inning of a baseball game against the St. Louis Cardinals Saturday, Sept. 21, 2024, in St. Louis.
AP Photo/Jeff Roberson
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  • The Guardians are -140 favorites vs the Rays
  • Rays vs Guardians Over / Under today: 7.5 Runs
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The Tampa Bay Rays (+118) visit Progressive Field to take on the Cleveland Guardians (-140) on April 27, 2026. First pitch is scheduled for 6:10 pm in Cleveland, OH.

This season, the Rays are 16-11 against the spread (ATS), while the Guardians are 15-14 ATS.

Rays vs Guardians Starting Pitchers Today:

  • Rays starting pitcher: Steven Matz 3-1, 4.88 ERA
  • Guardians starting pitcher: Parker Messick 3-0, 1.80 ERA

Rays vs. Guardians Odds, Run Line, Over/Under & Moneyline

Rays vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Monday‘s MLB game with 57.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Rays players for Monday‘s game, looking at profitable historical betting trends:

Best Rays Player Prop Bets Today:

  • Junior Caminero has hit the Home Runs Over in 4 of his last 7 away games (+11.75 Units / 168% ROI)
  • Junior Caminero has hit the Singles Over in 14 of his last 20 away games (+9.40 Units / 46% ROI)
  • Chandler Simpson has hit the Hits Over in 16 of his last 25 games (+9.40 Units / 23% ROI)
  • Yandy Diaz has hit the Hits Runs and RBIs Over in 12 of his last 15 away games (+8.65 Units / 45% ROI)
  • Junior Caminero has hit the RBIs Over in 6 of his last 7 away games (+7.65 Units / 109% ROI)

And here are some favorite MLB player prop bets for Guardians players for Monday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

  • Daniel Schneemann has hit the Home Runs Over in 3 of his last 9 games (+17.50 Units / 194% ROI)
  • Daniel Schneemann has hit the Total Bases Over in 13 of his last 15 games (+11.00 Units / 56% ROI)
  • Daniel Schneemann has hit the Hits Over in 13 of his last 15 games (+10.50 Units / 50% ROI)
  • Daniel Schneemann has hit the Hits Runs and RBIs Over in 12 of his last 15 games (+9.30 Units / 51% ROI)
  • Daniel Schneemann has hit the Runs Over in 7 of his last 9 games (+9.05 Units / 101% ROI)
  • The Tampa Bay Rays have hit the Team Total Over in 29 of their last 45 games (+10.95 Units / 20% ROI)
  • The Tampa Bay Rays have hit the 1st Five Innings (F5) Team Total Over in 26 of their last 40 away games (+10.00 Units / 21% ROI)
  • The Tampa Bay Rays have covered the Run Line in 14 of their last 20 games (+9.70 Units / 39% ROI)
  • The Tampa Bay Rays have hit the Game Total Over in 23 of their last 40 away games (+8.45 Units / 19% ROI)
  • The Tampa Bay Rays have hit the Moneyline in 14 of their last 20 games (+8.20 Units / 35% ROI)
  • The Cleveland Guardians have hit the Moneyline in 30 of their last 50 games (+11.30 Units / 19% ROI)
  • The Cleveland Guardians have covered the Run Line in 21 of their last 35 games at home (+10.70 Units / 25% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 30 of their last 50 games (+7.20 Units / 12% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 29 of their last 50 games (+7.05 Units / 12% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 28 of their last 50 games (+6.05 Units / 11% ROI)

Rays Against the Spread (ATS) Record

Against the spread this season, the Rays are 16-11 against the Run Line (+5.25 Units / 15.2% ROI).

  • 16-11 when betting on the Moneyline for +4.95 Units / 15.71% ROI
  • 16-9 when betting on the total runs Over for +6 Units / 20.34% ROI
  • 9-16 when betting on the total runs Under for -8.95 Units / -29.93% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 15-14 against the Run Line (+0.25 Units / 0.68% ROI).

  • 15-14 when betting on the Moneyline for +2.4 Units / 7.24% ROI
  • 15-14 when betting on the total runs Over for -0.15 Units / -0.47% ROI
  • 14-15 when betting on the total runs Under for -2.5 Units / -7.79% ROI

Guardians vs Rays Home Run Prop Bets Today

Yes
Junior Caminero +340
Jose Ramirez +375
David Fry +475
Rhys Hoskins +475
Yandy Diaz +550

Guardians vs Rays Total Hits Prop Bets Today

Over Under
Jose Ramirez 0.5 -275 0.5 +200
Steven Kwan 0.5 -275 0.5 +190
Junior Caminero 0.5 -250 0.5 +180
Angel Martinez 0.5 -235 0.5 +170
Chandler Simpson 0.5 -225 0.5 +165

Guardians vs Rays Strikeout Prop Bets Today

Over Under
David Fry 0.5 -250 0.5 +180
Daniel Schneemann 0.5 -250 0.5 +180
Taylor Walls 0.5 -235 0.5 +175
Juan Brito 0.5 -210 0.5 +155
Austin Hedges 0.5 -200 0.5 +145

Rays Keys to the Game vs. the Guardians

The Rays are 13-0 (1.000) when allowing 4 or fewer runs this season — best in MLB; League Avg: .728.

The Rays are 11-4 (.733) after a win this season — best in MLB; League Avg: .527.

The Rays are just 0-10 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .104.

The Rays are 13-0 (1.000) when leading entering the 7th inning this season — tied for best in MLB; League Avg: .858.

Guardians Keys to the Game vs. the Rays

The Guardians are 38-4 (.884) when they’ve had 10 or more hits since the 2025 season — 2nd best in MLB; League Avg: .747.

The Guardians are 11-2 (.846) after a loss this season — 2nd best in MLB; League Avg: .473.

The Guardians are 9-0 (1.000) when leading entering the 7th inning this season — tied for best in MLB; League Avg: .858.

The Guardians are just 0-13 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .050.

Rays hitters have struck out in just 18% of their PA’s against RHP this season — best in MLB.

Rays hitters have missed on just 19% of swings this season — best in MLB.

Rays hitters have a Hard-Hit Rate of just 35% in non-two strike counts this season — lowest in MLB.

The Rays are batting .214 on pitches out of the zone this season — 2nd best in MLB.

Guardians hitters have struck out in 35% of their PA’s in righty-righty matchups this season — highest in MLB.

7% of Guardians’ hitters plate appearances have lasted only one pitch (81/1,076 PA’s) this season — lowest in MLB.

Guardians hitters have an OPS of just .574 (806 PA’s) in righty-righty matchups since the 2025 season — lowest in MLB.

Guardians hitters have struck out in 32% of their PA’s in righty-righty matchups since the 2025 season — highest in MLB.

Opponents have a groundball rate of just 40% against Rays pitchers this season — 3rd lowest in MLB.

Rays pitchers have a strikeout rate of 25% with runners in scoring position since the 2025 season — best in MLB.

Rays pitchers have a strikeout rate of just 18% versus hitters not batting 3-4-5 in the order this season — 2nd lowest in MLB.

Opponents have a groundball rate of just 38% against Rays pitchers this month (22 games) — 2nd lowest in MLB.

Guardians pitchers have a strikeout rate of 36% in close and late situations this season — best in MLB.

Guardians pitchers have struck out 27% of left-handed batters they faced this season — best in MLB.

Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.

Guardians pitchers have a strikeout rate of 25% this season — 2nd best in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.