Red Sox vs Blue Jays Prediction, Odds & Player Prop Bets Today – MLB, Apr 28

Toronto Blue Jays Vladimir Guerrero Jr. gestures after hitting a home run during the first inning of a baseball game against the Boston Red Sox, Sunday, June 29, 2025, in Boston.
(AP Photo/Mark Stockwell)
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  • The Red Sox are +100 favorites vs the Blue Jays
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The Boston Red Sox (+100) visit Rogers Centre to take on the Toronto Blue Jays (-120) on April 28, 2026. First pitch is scheduled for 7:07 pm in Toronto, ON.

This season, the Red Sox are 12-17 against the spread (ATS), while the Blue Jays are 10-18 ATS.

Red Sox vs Blue Jays Starting Pitchers Today:

  • Red Sox starting pitcher: Payton Tolle 0-0, 1.50 ERA
  • Blue Jays starting pitcher: Trey Yesavage 0-0, 0.00 ERA

Red Sox vs. Blue Jays Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Red Sox-1.5 +170O 7.5 -105+100
Blue Jays +1.5 -210U 7.5 -115-120

Red Sox vs Blue Jays Prediction for Today’s Game

Based on recent trends the model predicts the Blue Jays will win Tuesday‘s MLB game with 53.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Red Sox players for Tuesday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Bets Today:

  • Jarren Duran has hit the Runs Over in 15 of his last 25 games (+9.30 Units / 37% ROI)
  • Jarren Duran has hit the Hits Under in 11 of his last 20 away games (+7.90 Units / 40% ROI)
  • Roman Anthony has hit the Walks Over in his last 6 games (+7.35 Units / 110% ROI)
  • Marcelo Mayer has hit the Singles Over in 7 of his last 8 away games (+7.25 Units / 90% ROI)
  • Roman Anthony has hit the Hits Runs and RBIs Over in 16 of his last 25 away games (+6.40 Units / 21% ROI)

And here are some favorite MLB player prop bets for Blue Jays players for Tuesday‘s game, looking at profitable historical betting trends:

Best Blue Jays Player Prop Best Bets Today:

  • Kazuma Okamoto has hit the Home Runs Over in 3 of his last 8 games (+13.40 Units / 167% ROI)
  • Davis Schneider has hit the Hits Runs and RBIs Under in 18 of his last 25 games (+11.25 Units / 37% ROI)
  • Davis Schneider has hit the Total Bases Under in 18 of his last 25 games (+9.35 Units / 30% ROI)
  • Vladimir Guerrero Jr has hit the Singles Over in 15 of his last 20 games (+8.60 Units / 33% ROI)
  • Davis Schneider has hit the Hits Under in his last 7 games (+7.75 Units / 97% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Over in 10 of their last 11 away games (+8.80 Units / 61% ROI)
  • The Boston Red Sox have hit the Game Total Under in 29 of their last 50 games (+7.00 Units / 13% ROI)
  • The Boston Red Sox have hit the Team Total Over in 7 of their last 9 away games (+5.15 Units / 55% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 4 of their last 5 games (+3.60 Units / 70% ROI)
  • The Boston Red Sox have hit the Moneyline in 4 of their last 5 away games (+3.35 Units / 63% ROI)
  • The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 23 of their last 30 games (+16.30 Units / 44% ROI)
  • The Toronto Blue Jays have hit the Team Total Over in 30 of their last 50 games at home (+8.25 Units / 14% ROI)
  • The Toronto Blue Jays have covered the Run Line in 5 of their last 8 games (+3.25 Units / 35% ROI)
  • The Toronto Blue Jays have hit the Game Total Over in 5 of their last 7 games at home (+2.85 Units / 37% ROI)
  • The Toronto Blue Jays have hit the Moneyline in 5 of their last 8 games (+1.65 Units / 17% ROI)

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 10-19 against the Run Line (-9.6 Units / -27.23% ROI).

  • 12-17 when betting on the Moneyline for -9.15 Units / -24.9% ROI
  • 15-14 when betting on the total runs Over for -0.5 Units / -1.56% ROI
  • 14-15 when betting on the total runs Under for -2.45 Units / -7.68% ROI

Blue Jays Against the Spread (ATS) Record

Against the spread this season, the Blue Jays are 10-18 against the Run Line (-9 Units / -26.75% ROI).

  • 12-16 when betting on the Moneyline for -10.45 Units / -25.96% ROI
  • 14-14 when betting on the total runs Over for -1.35 Units / -4.37% ROI
  • 14-14 when betting on the total runs Under for -1.25 Units / -4.07% ROI

Blue Jays vs Red Sox Home Run Prop Bets Today

Yes
Vladimir Guerrero Jr. +390
Kazuma Okamoto +400
Wilyer Abreu +425
Willson Contreras +450
Daulton Varsho +500

Blue Jays vs Red Sox Total Hits Prop Bets Today

Over Under
Vladimir Guerrero Jr. 0.5 -250 0.5 +185
Eloy Jimenez 0.5 -190 0.5 +140
Myles Straw 0.5 -175 0.5 +130
Wilyer Abreu 0.5 -165 0.5 +125
Jarren Duran 0.5 -165 0.5 +125

Blue Jays vs Red Sox Strikeout Prop Bets Today

Over Under
Ceddanne Rafaela 0.5 -275 0.5 +200
Eloy Jimenez 0.5 -200 0.5 +145
Daulton Varsho 0.5 -185 0.5 +135
Trey Yesavage 5.5 -160 5.5 +120
Tyler Heineman 0.5 -150 0.5 +110

Red Sox Keys to the Game vs. the Blue Jays

The Red Sox are just 0-16 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .054.

The Red Sox are just 0-15 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .109.

The Red Sox are 11-0 (1.000) when leading entering the 8th inning this season — tied for best in MLB; League Avg: .891.

The Red Sox are just 1-11 (.083) when allowing 10 or more hits this season — 3rd lowest in MLB; League Avg: .230.

Blue Jays Keys to the Game vs. the Red Sox

The Blue Jays are 14-66 (.175) when trailing entering the 8th inning since the 2025 season — best in MLB; League Avg: .093.

The Blue Jays are 79-6 (.929) when scoring 5 or more runs since the 2025 season — best in MLB; League Avg: .793.

The Blue Jays are 7-70 (.091) when trailing entering the 9th inning since the 2025 season — best in MLB; League Avg: .045.

The Blue Jays are 17-63 (.212) when trailing entering the 7th inning since the 2025 season — 2nd best in MLB; League Avg: .128.

Red Sox hitters have an OPS of just .603 (465 PA’s) at home this season — lowest in MLB.

Red Sox hitters are slugging just .312 at home this season — lowest in MLB.

The Red Sox are batting just .211 at home this season — 2nd lowest in MLB.

Red Sox hitters are slugging just .356 this season — 3rd lowest in MLB.

Blue Jays hitters have struck out in just 18% of their PA’s since the 2025 season — best in MLB.

Blue Jays hitters have struck out in just 18% of their PA’s against RHP since the 2025 season — best in MLB.

The Blue Jays are batting .181 on pitches out of the zone since the 2025 season — best in MLB.

Blue Jays hitters have struck out in just 18% of their PA’s against LHP since the 2025 season — best in MLB.

Red Sox pitchers have walked 4% of batters when facing the leadoff batter in the inning this season — best in MLB.

Opponents have a groundball batting average of just .196 against Red Sox pitchers this season — best in MLB.

Opponents have a groundball rate of 45% against Red Sox pitchers since the 2025 season — 4th highest in MLB.

Red Sox pitchers have walked 6% of batters over the past seven days (7 games) — best in MLB.

Blue Jays pitchers have a strikeout rate of 26% this season — best in MLB.

Blue Jays pitchers have a strikeout rate of 46% with two-strikes this season — best in MLB.

Blue Jays pitchers have walked 9% of batters when facing the leadoff batter in the inning since the 2025 season — tied for 5th highest in MLB.

Opponents have a miss rate of 27% against Blue Jays pitchers since the 2025 season — 5th best in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.