• The Red Sox are -135 favorites vs the Cardinals
• Red Sox vs Cardinals Over / Under today: 9 Runs
• Red Sox / Cardinals TV Channel: NESN | CATV

The Boston Red Sox (-135) visit Busch Stadium to take on the St. Louis Cardinals (+110) on April 12, 2026. First pitch is scheduled for 2:15 pm in St. Louis, MO.

This season, the Red Sox are 5-9 against the spread (ATS), while the Cardinals are 7-6 ATS.

Red Sox vs Cardinals Starting Pitchers Today:

• Red Sox starting pitcher: Brayan Bello 0-1, 9.01 ERA
• Cardinals starting pitcher: Andre Pallante 1-0, 1.80 ERA

Red Sox vs. Cardinals Odds, Run Line, Over/Under & Moneyline

Red Sox vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Red Sox will win Sunday‘s MLB game with 51.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Red Sox players for Sunday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Bets Today:

• Caleb Durbin has hit the Hits Under in 15 of his last 25 games (+11.00 Units / 44% ROI)
• Caleb Durbin has hit the Hits Runs and RBIs Under in 19 of his last 25 away games (+10.60 Units / 30% ROI)
• Caleb Durbin has hit the Total Bases Under in 16 of his last 25 games (+9.55 Units / 30% ROI)
• Caleb Durbin has hit the Singles Under in 12 of his last 15 away games (+8.35 Units / 44% ROI)
• Wilyer Abreu has hit the Home Runs Over in 3 of his last 7 away games (+7.90 Units / 113% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Sunday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

• Jordan Walker has hit the Home Runs Over in 5 of his last 7 games (+27.40 Units / 391% ROI)
• Jordan Walker has hit the Runs Over in 13 of his last 20 games (+13.25 Units / 66% ROI)
• Masyn Winn has hit the Total Bases Under in 18 of his last 25 games at home (+9.85 Units / 25% ROI)
• Andre Pallante has hit the Pitching Outs Under in 12 of his last 15 games (+8.95 Units / 50% ROI)
• Thomas Saggese has hit the Hits Over in 19 of his last 25 games (+8.75 Units / 20% ROI)

Red Sox Best Bets Today:

• The Boston Red Sox have hit the Game Total Under in 22 of their last 35 games (+8.70 Units / 23% ROI)
• The Boston Red Sox have hit the Team Total Under in 14 of their last 21 games (+6.20 Units / 24% ROI)
• The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Under in 21 of their last 35 away games (+5.40 Units / 13% ROI)
• The Boston Red Sox have covered the 1st Five Innings (F5) Run Line in 3 of their last 5 games (+1.00 Units / 18% ROI)
• The Boston Red Sox have hit the Moneyline in 26 of their last 50 away games (+0.70 Units / 1% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 21 of their last 35 games at home (+7.55 Units / 19% ROI)
• The St. Louis Cardinals have hit the Team Total Under in 24 of their last 40 games at home (+6.05 Units / 13% ROI)
• The St. Louis Cardinals have hit the Moneyline in 12 of their last 19 games at home (+5.90 Units / 30% ROI)
• The St. Louis Cardinals have hit the Game Total Under in 21 of their last 35 games at home (+5.40 Units / 14% ROI)
• The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 8 of their last 11 games at home (+4.60 Units / 33% ROI)

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 4-10 against the Run Line (-5.8 Units / -37.79% ROI).

• 5-9 when betting on the Moneyline for -6.8 Units / -35.88% ROI
• 7-7 when betting on the total runs Over for -0.7 Units / -4.58% ROI
• 7-7 when betting on the total runs Under for -0.75 Units / -4.81% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 7-6 against the Run Line (-1 Units / -5.15% ROI).

• 8-6 when betting on the Moneyline for +3.1 Units / 21.45% ROI
• 7-6 when betting on the total runs Over for +0.5 Units / 3.31% ROI
• 6-7 when betting on the total runs Under for -2 Units / -12.66% ROI

Red Sox Keys to the Game vs. the Cardinals

The Red Sox are just 5-9 (.357) this season — 2nd lowest in MLB; League Avg: .500.

The Red Sox are just 0-8 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .026.

The Red Sox are just 5-8 (.385) when allowing 5 or more extra base hits this season — tied for 2nd lowest in MLB; League Avg: .521.

The Red Sox were 71-4 (.947) when leading entering the 8th inning in the 2025 season — tied for 2nd best in MLB; League Avg: .909.

Cardinals Keys to the Game vs. the Red Sox

The Cardinals are just 0-6 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .026.

The Cardinals were just 7-11 (.389) when tied entering the 8th inning in the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

The Cardinals are 28-18 (.609) when tied entering the 7th inning since the 2024 season — tied for 4th best in MLB; League Avg: .499.

The Cardinals are just 8-12 (.400) when tied entering the 8th inning since the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

Red Sox Hitting Stats & Trends

Red Sox hitters have chased 23% of pitches out of the zone against LHP this season — 2nd lowest in MLB.

Red Sox hitters have struck out in just 16% of their PA’s against LHP this season — 2nd best in MLB.

Red Sox hitters have put 46% of their swings in play against LHP this season — highest in MLB.

The Red Sox are batting .257 against LHP since the 2025 season — tied for 4th best in MLB.

Cardinals Hitting Stats & Trends

The Cardinals are batting just .108 when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.

The Cardinals are batting just .161 with two outs this season — 2nd lowest in MLB.

The Cardinals batted just .221 with two outs in the 2025 season — tied for 4th lowest in MLB.

Cardinals hitters had an OPS of just .941 (1,172 PA’s) when the pitcher was behind in the count in the 2025 season — 2nd lowest in MLB.

Red Sox Pitching Stats & Trends

Opponents had a groundball rate of 46% against Red Sox pitchers in the 2025 season — 4th highest in MLB.

Red Sox pitchers have walked 5% of batters when facing the leadoff batter in the inning this season — 3rd best in MLB.

The longest HR allowed by the Red Sox pitchers in the 2025 season traveled 511.8 feet — — 2nd longest in MLB

Opponents have a groundball batting average of just .174 against Red Sox pitchers with runners on base this season — 3rd best in MLB.

Cardinals Pitching Stats & Trends

Cardinals pitchers have a strikeout rate of just 15% this season — lowest in MLB.

Cardinals pitchers have a strikeout rate of just 33% with two-strikes this season — lowest in MLB.

Opponents have a miss rate of just 19% against Cardinals pitchers this month (9 games) — lowest in MLB.

Opponents have a miss rate of just 19% against Cardinals pitchers this season — lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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