Red Sox vs Phillies Prediction, Odds & Player Prop Bets Today – MLB, Jul 21

FILE - Philadelphia Phillies' Brandon Marsh hits a home run during the eighth inning of Game 3 of a baseball NL Division Series against the Atlanta Braves Wednesday, Oct. 11, 2023, in Philadelphia. Brandon Marsh underwent successful left knee arthroscopic debridement surgery with Dr. Steven Cohen in Philadelphia, Friday morning Feb. 9, 2024. It is anticipated he will return to playing in three to four weeks and be ready to play opening day.(AP Photo/Matt Rourke, File)
(AP Photo/Matt Rourke)
  • The Phillies are -220 favorites vs the Red Sox
  • Red Sox vs Phillies Over / Under today: 8.5 Runs
  • Red Sox / Phillies TV Channel: NESN | NSPA

The Boston Red Sox (+180) visit Citizens Bank Park to take on the Philadelphia Phillies (-220) on Monday, July 21, 2025. First pitch is scheduled for 6:45pm EDT in Philadelphia, PA.

This season, the Red Sox are 54-47 against the spread (ATS), while the Phillies are 49-49 ATS.

Red Sox vs Phillies Starting Pitchers Today:

  • Red Sox starting pitcher: Walker Buehler 6-6, 6.15 ERA
  • Phillies starting pitcher: Zack Wheeler 9-3, 2.36 ERA

Red Sox vs. Phillies Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Red Sox+1.5 -115O 8 -115+180
Phillies -1.5 -105U 8 -105-220

Red Sox vs Phillies Prediction for Today’s Game

Based on recent trends the model predicts the Phillies will win Monday‘s MLB game with 64.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Red Sox players for Monday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Bets Today:

  • Ceddanne Rafaela has hit the Home Runs Over in 4 of his last 10 games (+15.90 Units / 159% ROI)
  • Ceddanne Rafaela has hit the Runs Over in 16 of his last 25 games (+12.15 Units / 48% ROI)
  • Roman Anthony has hit the Hits Over in 17 of his last 20 games (+11.55 Units / 29% ROI)
  • Roman Anthony has hit the Hits Runs and RBIs Over in 16 of his last 20 games (+11.50 Units / 49% ROI)
  • Jarren Duran has hit the Walks Over in 6 of his last 7 games (+9.20 Units / 131% ROI)

And here are some favorite MLB player prop bets for Phillies players for Monday‘s game, looking at profitable historical betting trends:

Best Phillies Player Prop Best Bets Today:

  • Trea Turner has hit the Singles Over in 20 of his last 25 games at home (+12.85 Units / 36% ROI)
  • Kyle Schwarber has hit the Home Runs Over in 5 of his last 8 games (+12.25 Units / 153% ROI)
  • Zack Wheeler has hit the Strikeouts Over in 18 of his last 25 games (+11.15 Units / 37% ROI)
  • Max Kepler has hit the Hits Runs and RBIs Under in 16 of his last 20 games (+10.80 Units / 42% ROI)
  • J.T. Realmuto has hit the RBIs Under in his last 10 games at home (+10.00 Units / 42% ROI)
  • The Boston Red Sox have hit the Moneyline in 24 of their last 36 games (+13.15 Units / 26% ROI)
  • The Boston Red Sox have covered the 1st Five Innings (F5) Run Line in 25 of their last 38 away games (+12.10 Units / 27% ROI)
  • The Boston Red Sox have covered the Run Line in 12 of their last 16 games (+8.00 Units / 39% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 22 of their last 44 away games (+6.25 Units / 11% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Under in their last 5 games (+5.40 Units / 97% ROI)
  • The Philadelphia Phillies have hit the Team Total Under in 33 of their last 50 games (+13.51 Units / 23% ROI)
  • The Philadelphia Phillies have hit the 1st Five Innings (F5) Moneyline in 42 of their last 81 games (+10.90 Units / 8% ROI)
  • The Philadelphia Phillies have hit the Game Total Under in 43 of their last 76 games (+10.15 Units / 12% ROI)
  • The Philadelphia Phillies have hit the 1st Five Innings (F5) Team Total Under in 58 of their last 99 games (+9.54 Units / 8% ROI)
  • The Philadelphia Phillies have covered the Run Line in 18 of their last 32 games (+5.10 Units / 14% ROI)

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 53-47 against the Run Line (+5.1 Units / 3.97% ROI).

  • 54-47 when betting on the Moneyline for -1.66 Units / -1.2% ROI
  • 48-51 when betting on the total runs Over for -8.31 Units / -7.47% ROI
  • 51-48 when betting on the total runs Under for -1.95 Units / -1.76% ROI

Phillies Against the Spread (ATS) Record

Against the spread this season, the Phillies are 49-49 against the Run Line (-2.4 Units / -1.98% ROI).

  • 56-43 when betting on the Moneyline for -1.25 Units / -0.81% ROI
  • 42-54 when betting on the total runs Over for -17.1 Units / -15.71% ROI
  • 54-42 when betting on the total runs Under for +8.05 Units / 7.39% ROI

Phillies vs Red Sox Home Run Prop Bets Today

Over Under
Kyle Schwarber (PHI) 0.5 +290 0.5 -350
Bryce Harper (PHI) 0.5 +333 0.5 -450
Wilyer Abreu (BOS) 0.5 +400 0.5 -525
Alex Bregman (BOS) 0.5 +525 0.5 -750
Jarren Duran (BOS) 0.5 +525 0.5 -750

Phillies vs Red Sox Total Hits Prop Bets Today

Over Under
Bryce Harper (PHI) 0.5 -235 0.5 +180
J.T. Realmuto (PHI) 0.5 -235 0.5 +180
Alex Bregman (BOS) 0.5 -190 0.5 +145
Jarren Duran (BOS) 0.5 -175 0.5 +130
Ceddanne Rafaela (BOS) 0.5 -165 0.5 +125

Phillies vs Red Sox RBI Prop Bets Today

Over Under
Nick Castellanos (PHI) 0.5 +130 0.5 -165
Bryce Harper (PHI) 0.5 +140 0.5 -185
Kyle Schwarber (PHI) 0.5 +140 0.5 -185
J.T. Realmuto (PHI) 0.5 +175 0.5 -235
Trea Turner (PHI) 0.5 +180 0.5 -250

Phillies vs Red Sox Strikeout Prop Bets Today

Over Under
Walker Buehler (BOS) 3.5 -165 3.5 +125
Zack Wheeler (PHI) 7.5 -155 7.5 +120

Hitters have swung at 36% of Walker Buehler’s fastballs (201/552) this season — lowest in MLB among starting pitchers with at least 39 total IP; League Avg: 48% — 0 Percentile.

Opponents are hitting .322 (82-for-255) against Walker Buehler when going through the lineup the first time in a game since last season — highest in MLB among starting pitchers with at least 103 total IP; League Avg: .236 — 0 Percentile.

Walker Buehler has allowed an OBP of .389 (144 PA’s) when going through the lineup the first time in a game this season — 2nd highest in MLB among starting pitchers with at least 39 total IP; League Avg: .301 — first Percentile.

Walker Buehler has allowed an OBP of .337 (190 PA’s) with two-strikes this season — highest in MLB among starting pitchers with at least 39 total IP; League Avg: .243 — 0 Percentile.

Phillies Starting Pitcher Stats & Trends

Right-handed batters batted just .161 (56-for-348) against Zack Wheeler in the 2024 season — best among qualified SPs in MLB; League Avg: .234 — 100th Percentile.

Zack Wheeler has struck out 34% (90/264) of left-handed batters he faced this season — best among qualified SPs in MLB; League Avg: 22% — 100th Percentile.

Zack Wheeler has thrown inside pitches 46% of the time (593/1,302) in non-two strike counts this season — highest among among NL Starters; League Avg: 31% — 100th Percentile.

Zack Wheeler allowed an OBP of just .201 (368 PA’s) against right-handed batters in the 2024 season — best among qualified SPs in MLB; League Avg: .289 — 100th Percentile.

Red Sox Keys to the Game vs. the Phillies

The Red Sox are 32-21 (.604) after a win this season — 4th best in MLB; League Avg: .506.

The Red Sox were just 5-58 (.079) when trailing entering the 7th inning in the 2024 season — 3rd lowest in MLB; League Avg: .143.

The Red Sox are 45-3 (.938) when leading entering the 8th inning this season — tied for 5th best in MLB; League Avg: .906.

The Red Sox were just 18-69 (.207) when they scored 4 or fewer runs in the 2024 season — 4th lowest in MLB; League Avg: .276.

Phillies Keys to the Game vs. the Red Sox

The Phillies are 9-27 (.250) when trailing entering the 7th inning this season — best in MLB; League Avg: .123.

The Phillies are 15-9 (.625) vs top 10 scoring offenses this season They play the Red Sox (Ranks fifth runs scored) today.

The Phillies are just 13-27 (.325) when tied entering the 7th inning since last season — 2nd lowest in MLB; League Avg: .499.

The Phillies are 21-74 (.221) when trailing entering the 7th inning since last season — best in MLB; League Avg: .136.

Red Sox hitters have put just 33% of their swings in play against LHP since last season — lowest in MLB; League Avg: 37%.

Red Sox hitters are slugging .445 against LHP this season — 4th best in MLB; League Avg: .386.

Red Sox hitters have an OPS of .786 (1,127 PA’s) against LHP this season — 3rd best in MLB; League Avg: .695.

The Red Sox have an average Exit Velocity of 91.8 MPH this month (15 games) — best in MLB; League Avg: 89.3.

The Phillies are batting .394 on the first pitch of at-bats this season — best in MLB; League Avg: .340.

Phillies hitters have chased 32% of pitches out of the zone against LHP this season — highest in MLB; League Avg: 29%.

Phillies hitters have an OPS of .809 (454 PA’s) in lefty-lefty matchups this season — best in MLB; League Avg: .658.

Phillies hitters have chased 20% of pitches out of the zone on the first pitch of at-bats this season — highest in MLB; League Avg: 16%.

Opponents have a groundball rate of 46% against Red Sox pitchers this season — 4th highest in MLB; League Avg: 42%.

Red Sox pitchers have walked 5% of batters over the last 14 days — best in MLB; League Avg: 8%.

Red Sox pitchers have an ERA of 2.25 (88.0 IP) over the last 14 days — best in MLB; League Avg: 4.34.

Opponents had a miss rate of just 24% against Red Sox pitchers in the 2024 season — tied for 2nd lowest in MLB; League Avg: 25%.

The Phillies pitchers have allowed their opponents to score first in just 39% of their games at home this season — lowest in MLB; League Avg: 55%.

Phillies pitchers have a strikeout rate of 45% with two-strikes since last season — 3rd best in MLB; League Avg: 42%.

Phillies pitchers have walked 7% of batters when facing the leadoff batter in the inning this season — 5th best in MLB; League Avg: 8%.

Batters facing the Phillies pitchers have struck out on pitches in the zone 70% of the time over the past seven days (3 games) — 2nd highest in MLB; League Avg: 50%. over the past seven days (3 games) — 2nd highest in MLB; League Avg: 50%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.