• The Tigers are -235 favorites vs the Red Sox
• Red Sox vs Tigers Over / Under today: 7 Runs
• Red Sox / Tigers TV Channel: NESN | DSN

The Boston Red Sox (+190) visit Comerica Park to take on the Detroit Tigers (-235) on May 4, 2026. First pitch is scheduled for 6:40 pm in Detroit, MI.

This season, the Red Sox are 13-21 against the spread (ATS), while the Tigers are 16-17 ATS.

Red Sox vs Tigers Starting Pitchers Today:

• Red Sox starting pitcher: Payton Tolle 0-1, 3.49 ERA
• Tigers starting pitcher: Tarik Skubal 3-2, 2.70 ERA

Red Sox vs. Tigers Odds, Run Line, Over/Under & Moneyline

Red Sox vs Tigers Prediction for Today’s Game

Based on recent trends the model predicts the Tigers will win Monday‘s MLB game with 69.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Red Sox players for Monday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Bets Today:

• Carlos Narvaez has hit the Home Runs Over in 2 of his last 6 games (+16.00 Units / 267% ROI)
• Roman Anthony has hit the Runs Under in 19 of his last 25 games (+11.55 Units / 33% ROI)
• Wilyer Abreu has hit the Total Bases Over in 14 of his last 20 away games (+9.45 Units / 39% ROI)
• Wilyer Abreu has hit the Walks Over in 7 of his last 10 away games (+9.05 Units / 90% ROI)
• Ceddanne Rafaela has hit the Hits Runs and RBIs Under in 12 of his last 15 games (+8.45 Units / 45% ROI)

And here are some favorite MLB player prop bets for Tigers players for Monday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Best Bets Today:

• Dillon Dingler has hit the Home Runs Over in 3 of his last 7 games at home (+19.60 Units / 280% ROI)
• Wenceel Perez has hit the Total Bases Under in 19 of his last 25 games (+15.00 Units / 49% ROI)
• Wenceel Perez has hit the Hits Under in 12 of his last 15 games at home (+13.55 Units / 90% ROI)
• Wenceel Perez has hit the Runs Under in 14 of his last 15 games at home (+12.00 Units / 42% ROI)
• Riley Greene has hit the Walks Over in 14 of his last 25 games (+11.10 Units / 44% ROI)

Red Sox Best Bets Today:

• The Boston Red Sox have hit the Team Total Under in 26 of their last 40 games (+9.60 Units / 20% ROI)
• The Boston Red Sox have hit the Game Total Over in 11 of their last 15 away games (+6.65 Units / 40% ROI)
• The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Over in 10 of their last 13 away games (+6.40 Units / 38% ROI)
• The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 6 of their last 10 games (+2.00 Units / 17% ROI)
• The Boston Red Sox have hit the Moneyline in 3 of their last 5 away games (+1.15 Units / 22% ROI)

Tigers Best Bets Today:

• The Detroit Tigers have hit the Team Total Over in 30 of their last 45 games at home (+14.30 Units / 28% ROI)
• The Detroit Tigers have hit the Game Total Over in 30 of their last 50 games at home (+12.45 Units / 23% ROI)
• The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Over in 28 of their last 45 games at home (+11.10 Units / 21% ROI)
• The Detroit Tigers have hit the Moneyline in 13 of their last 16 games at home (+9.40 Units / 42% ROI)
• The Detroit Tigers have covered the Run Line in 10 of their last 16 games at home (+8.95 Units / 50% ROI)

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 11-23 against the Run Line (-12.4 Units / -30.81% ROI).

• 13-21 when betting on the Moneyline for -13.5 Units / -31.18% ROI
• 16-17 when betting on the total runs Over for -2.95 Units / -7.84% ROI
• 17-16 when betting on the total runs Under for -0.55 Units / -1.48% ROI

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 16-17 against the Run Line (+0.1 Units / 0.23% ROI).

• 18-17 when betting on the Moneyline for -2.1 Units / -4.69% ROI
• 16-17 when betting on the total runs Over for -2.75 Units / -7.11% ROI
• 17-16 when betting on the total runs Under for -0.45 Units / -1.17% ROI

Tigers vs Red Sox Home Run Prop Bets Today

Tigers vs Red Sox Total Hits Prop Bets Today

Tigers vs Red Sox Strikeout Prop Bets Today

Red Sox Keys to the Game vs. the Tigers

The Red Sox are 12-0 (1.000) when leading entering the 8th inning this season — tied for best in MLB; League Avg: .889.

The Red Sox are 83-4 (.954) when leading entering the 8th inning since the 2025 season — best in MLB; League Avg: .906.

The Red Sox are just 0-18 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .111.

The Red Sox are just 0-19 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .056.

Tigers Keys to the Game vs. the Red Sox

The Tigers are 12-3 (.800) at home this season — best in MLB; League Avg: .534.

The Tigers are 5-12 (.294) when trailing entering the 8th inning this season — 2nd best in MLB; League Avg: .111.

The Tigers are 9-1 (.900) when they’ve scored in the first inning this season — 2nd best in MLB; League Avg: .633.

The Tigers are 39-13 (.750) when they’ve scored in the first inning since the 2025 season — 3rd best in MLB; League Avg: .636.

Red Sox Hitting Stats & Trends

Red Sox hitters are slugging just .344 against RHP this season — 2nd lowest in MLB.

Red Sox hitters have an OPS of just .656 (961 PA’s) against RHP this season — 3rd lowest in MLB.

Red Sox hitters are slugging just .353 this season — 2nd lowest in MLB.

Red Sox hitters are slugging just .324 at home this season — 3rd lowest in MLB.

Tigers Hitting Stats & Trends

The Tigers are batting .285 with two outs this season — best in MLB.

Tigers hitters have drawn walks in 14% of their PA’s against LHP this season — best in MLB.

The Tigers are batting .294 with runners on base this season — 2nd best in MLB.

Tigers hitters have an OBP of .336 (2,036 PA’s) against LHP since the 2025 season — best in MLB.

Red Sox Pitching Stats & Trends

Red Sox pitchers have walked 5% of batters when facing the leadoff batter in the inning this season — best in MLB.

Opponents have a groundball batting average of just .204 against Red Sox pitchers this season — best in MLB.

Opponents have a groundball rate of 45% against Red Sox pitchers since the 2025 season — 4th highest in MLB.

Red Sox pitchers have allowed 44 home runs this season — tied for 4th most in MLB.

Tigers Pitching Stats & Trends

Tigers pitchers have walked 6% of batters when facing the leadoff batter in the inning since the 2025 season — tied for best in MLB.

Tigers pitchers have a first-pitch strike rate of 63% this season — 3rd highest in MLB.

Tigers pitchers have walked 7% of batters over the past seven days (6 games) — 5th best in MLB.

Tigers pitchers walked 416 of 5,969 batters (7%) in the 2024 season — 2nd best in MLB; League Avg: 8%.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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