• The Red Sox are +100 favorites vs the Tigers
• Red Sox vs Tigers Over / Under today: 8.5 Runs
• Red Sox / Tigers TV Channel: NESN | DSN | WJBK

The Boston Red Sox (+100) visit Comerica Park to take on the Detroit Tigers (-120) on May 6, 2026. First pitch is scheduled for 6:40 pm in Detroit, MI.

This season, the Red Sox are 15-21 against the spread (ATS), while the Tigers are 16-18 ATS.

Red Sox vs Tigers Starting Pitchers Today:

• Red Sox starting pitcher: Sonny Gray 2-1, 4.31 ERA
• Tigers starting pitcher: Jack Flaherty 0-2, 5.90 ERA

Red Sox vs. Tigers Odds, Run Line, Over/Under & Moneyline

Red Sox vs Tigers Prediction for Today’s Game

Based on recent trends the model predicts the Tigers will win Wednesday‘s MLB game with 52.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Red Sox vs Tigers and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Red Sox players for Wednesday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Bets Today:

• Jarren Duran has hit the Home Runs Over in 3 of his last 5 games (+17.70 Units / 354% ROI)
• Marcelo Mayer has hit the Runs Under in 18 of his last 20 games (+13.40 Units / 31% ROI)
• Wilyer Abreu has hit the Walks Over in 8 of his last 9 games (+11.65 Units / 129% ROI)
• Jarren Duran has hit the Hits Under in 14 of his last 25 away games (+10.55 Units / 42% ROI)
• Wilyer Abreu has hit the Total Bases Over in 17 of his last 25 away games (+10.30 Units / 34% ROI)

And here are some favorite MLB player prop bets for Tigers players for Wednesday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Best Bets Today:

• Dillon Dingler has hit the Home Runs Over in 3 of his last 9 games at home (+17.60 Units / 196% ROI)
• Wenceel Perez has hit the Total Bases Under in 19 of his last 25 games (+14.95 Units / 49% ROI)
• Kevin McGonigle has hit the Hits Over in 19 of his last 25 games (+13.00 Units / 27% ROI)
• Wenceel Perez has hit the Runs Under in 14 of his last 15 games at home (+12.00 Units / 41% ROI)
• Kevin McGonigle has hit the Walks Over in 10 of his last 15 games at home (+11.10 Units / 74% ROI)

Red Sox Best Bets Today:

• The Boston Red Sox have hit the Game Total Over in 13 of their last 17 away games (+8.65 Units / 46% ROI)
• The Boston Red Sox have hit the Team Total Under in 27 of their last 45 games (+5.90 Units / 11% ROI)
• The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Over in 11 of their last 15 away games (+5.80 Units / 29% ROI)
• The Boston Red Sox have hit the Moneyline in 5 of their last 7 away games (+3.45 Units / 46% ROI)
• The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 7 of their last 12 games (+3.25 Units / 23% ROI)

Tigers Best Bets Today:

• The Detroit Tigers have hit the Game Total Over in 28 of their last 45 games at home (+12.75 Units / 26% ROI)
• The Detroit Tigers have hit the Team Total Over in 29 of their last 45 games at home (+12.15 Units / 23% ROI)
• The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Over in 27 of their last 45 games at home (+8.30 Units / 16% ROI)
• The Detroit Tigers have covered the Run Line in 10 of their last 18 games at home (+7.95 Units / 39% ROI)
• The Detroit Tigers have hit the Moneyline in 13 of their last 18 games at home (+6.90 Units / 28% ROI)

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 12-23 against the Run Line (-11.4 Units / -26.57% ROI).

• 15-21 when betting on the Moneyline for -11.2 Units / -24.59% ROI
• 18-17 when betting on the total runs Over for -0.95 Units / -2.38% ROI
• 17-18 when betting on the total runs Under for -2.75 Units / -6.97% ROI

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 16-18 against the Run Line (-0.9 Units / -2% ROI).

• 18-19 when betting on the Moneyline for -4.6 Units / -9.74% ROI
• 18-17 when betting on the total runs Over for -0.75 Units / -1.83% ROI
• 17-18 when betting on the total runs Under for -2.65 Units / -6.54% ROI

Tigers vs Red Sox Home Run Prop Bets Today

Tigers vs Red Sox Total Hits Prop Bets Today

Tigers vs Red Sox Strikeout Prop Bets Today

Red Sox Keys to the Game vs. the Tigers

The Red Sox are just 4-17 (.190) when scoring 4 or fewer runs this season — 3rd lowest in MLB; League Avg: .275.

The Red Sox are 85-4 (.955) when leading entering the 8th inning since the 2025 season — best in MLB; League Avg: .906.

The Red Sox are 87-2 (.978) when leading entering the 9th inning since the 2025 season — tied for 2nd best in MLB; League Avg: .954.

The Red Sox are just 0-18 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .110.

Tigers Keys to the Game vs. the Red Sox

The Tigers are just 1-7 (.125) when their opponents score in the first inning this season — lowest in MLB; League Avg: .376.

The Tigers are 5-14 (.263) when trailing entering the 8th inning this season — 3rd best in MLB; League Avg: .110.

The Tigers are 39-14 (.736) when they’ve scored in the first inning since the 2025 season — 3rd best in MLB; League Avg: .634.

The Tigers are 90-25 (.783) when allowing 4 or fewer runs since the 2025 season — best in MLB; League Avg: .716.

Red Sox Hitting Stats & Trends

The Red Sox are batting .196 on pitches out of the zone this season — 3rd best in MLB.

The Red Sox are batting .260 against LHP since the 2025 season — best in MLB.

Red Sox hitters have an OPS of just .678 (1,364 PA’s) this season — 3rd lowest in MLB.

Red Sox hitters are slugging just .342 against RHP this season — 2nd lowest in MLB.

Tigers Hitting Stats & Trends

Tigers hitters have chased 23% of pitches out of the zone against LHP this season — lowest in MLB.

The Tigers are batting .278 with two outs this season — best in MLB.

The Tigers are batting just .212 against LHP this season — 5th lowest in MLB.

Tigers hitters have drawn walks in 10% of their PA’s against LHP since the 2025 season — 2nd best in MLB.

Red Sox Pitching Stats & Trends

Red Sox pitchers have walked 5% of batters when facing the leadoff batter in the inning this season — best in MLB.

Opponents have a groundball batting average of just .175 against Red Sox pitchers with runners on base this season — best in MLB.

Opponents have a groundball rate of 45% against Red Sox pitchers since the 2025 season — 4th highest in MLB.

Opponents have a groundball batting average of just .204 against Red Sox pitchers this season — best in MLB.

Tigers Pitching Stats & Trends

Tigers pitchers have walked 6% of batters when facing the leadoff batter in the inning since the 2025 season — 2nd best in MLB.

Opponents have a groundball batting average of just .236 against Tigers pitchers with runners on base since the 2025 season — 3rd best in MLB.

Tigers pitchers have walked 6% of batters over the past seven days (7 games) — 5th best in MLB.

Opponents have a groundball rate of 51% against Tigers pitchers over the past seven days (7 games) — 2nd highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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