• The Reds are -105 favorites vs the Cardinals
• Reds vs Cardinals Over / Under today: 8 Runs
• Reds / Cardinals TV Channel: CATV | RDTV

The Cincinnati Reds (-105) visit Busch Stadium to take on the St. Louis Cardinals (-115) on July 25, 2026. First pitch is scheduled for 7:15 pm in St. Louis, MO.

This season, the Reds are 48-54 against the spread (ATS), while the Cardinals are 57-43 ATS.

Reds vs Cardinals Starting Pitchers Today:

• Reds starting pitcher: Hunter Greene 2-1, 6.19 ERA
• Cardinals starting pitcher: Andre Pallante 10-6, 4.03 ERA

Reds vs. Cardinals Odds, Run Line, Over/Under & Moneyline

Reds vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Cardinals will win Saturday‘s MLB game with 51.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Reds vs Cardinals and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Reds players for Saturday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Bets Today:

• Eugenio Suarez has hit the Home Runs Over in 5 of his last 8 games (+17.30 Units / 216% ROI)
• Tyler Stephenson has hit the Hits Over in 17 of his last 20 away games (+13.75 Units / 47% ROI)
• Spencer Steer has hit the Singles Under in 17 of his last 20 away games (+12.55 Units / 48% ROI)
• Tyler Stephenson has hit the Total Bases Over in 16 of his last 20 away games (+11.05 Units / 39% ROI)
• Tyler Stephenson has hit the Hits Runs and RBIs Over in 15 of his last 20 away games (+10.35 Units / 43% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Saturday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

• Ivan Herrera has hit the Total Bases Under in 22 of his last 25 games at home (+17.60 Units / 42% ROI)
• Ivan Herrera has hit the Hits Runs and RBIs Under in 17 of his last 20 games at home (+14.05 Units / 62% ROI)
• Ivan Herrera has hit the Hits Under in 14 of his last 20 games at home (+13.75 Units / 50% ROI)
• Masyn Winn has hit the Runs Under in 14 of his last 15 games (+12.35 Units / 39% ROI)
• Alec Burleson has hit the Singles Under in 12 of his last 15 games at home (+9.15 Units / 56% ROI)

Reds Best Bets Today:

• The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Over in 28 of their last 45 away games (+8.40 Units / 15% ROI)
• The Cincinnati Reds have hit the Team Total Under in 30 of their last 50 games (+7.95 Units / 14% ROI)
• The Cincinnati Reds have hit the Moneyline in 10 of their last 16 away games (+6.50 Units / 38% ROI)
• The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 24 of their last 40 games (+6.35 Units / 14% ROI)
• The Cincinnati Reds have hit the Game Total Over in 29 of their last 50 away games (+5.90 Units / 11% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the Game Total Under in 16 of their last 20 games at home (+11.60 Units / 53% ROI)
• The St. Louis Cardinals have hit the Team Total Under in 31 of their last 50 games at home (+9.70 Units / 16% ROI)
• The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 31 of their last 50 games (+8.15 Units / 13% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 25 of their last 50 games (+6.30 Units / 11% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Over in 26 of their last 45 games (+5.85 Units / 11% ROI)

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 56-45 against the Run Line (-1.9 Units / -1.32% ROI).

• 48-54 when betting on the Moneyline for -5.25 Units / -4.62% ROI
• 56-45 when betting on the total runs Over for +6.45 Units / 5.72% ROI
• 45-56 when betting on the total runs Under for -16 Units / -14.33% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 57-43 against the Run Line (+2 Units / 1.37% ROI).

• 52-51 when betting on the Moneyline for +4.7 Units / 4.24% ROI
• 42-56 when betting on the total runs Over for -19.9 Units / -17.53% ROI
• 56-42 when betting on the total runs Under for +9.65 Units / 8.53% ROI

Cardinals vs Reds Home Run Prop Bets Today

Cardinals vs Reds Total Hits Prop Bets Today

Cardinals vs Reds Strikeout Prop Bets Today

Reds Keys to the Game vs. the Cardinals

The Reds are just 3-15 (.167) when tied entering the 7th inning this season — lowest in MLB; League Avg: .500.

The Reds are 5-47 (.096) when trailing entering the 9th inning this season — 2nd best in MLB; League Avg: .052.

The Reds are just 6-11 (.353) when tied entering the 8th inning this season — 5th lowest in MLB; League Avg: .500.

The Reds are just 5-28 (.152) when allowing 10 or more hits this season — 5th lowest in MLB; League Avg: .248.

Cardinals Keys to the Game vs. the Reds

The Cardinals were 69-1 (.986) when leading entering the 9th inning in the 2024 season — tied for 2nd best in MLB; League Avg: .949.

The Cardinals were just 7-11 (.389) when tied entering the 8th inning in the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.

Reds Hitting Stats & Trends

Reds hitters are slugging just .169 on pitches out of the zone this season — lowest in MLB.

The Reds are batting just .116 on pitches out of the zone this season — lowest in MLB.

The Reds are batting just .219 with runners on base this season — lowest in MLB.

The Reds are batting just .215 with two outs this season — lowest in MLB.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 18% of their PA’s against LHP this season — 2nd best in MLB.

The Cardinals are batting just .317 on the first pitch of at-bats this season — 5th lowest in MLB.

Cardinals hitters are slugging just .382 against RHP this season — 3rd lowest in MLB.

Cardinals hitters have struck out in just 17% of their PA’s in lefty-lefty matchups this season — best in MLB.

Reds Pitching Stats & Trends

Reds pitchers have walked 11% of batters this season — tied for 2nd highest in MLB.

The Reds pitchers have allowed their opponents to score first in 66% of their games at home this season — tied for 2nd highest in MLB.

Reds pitchers have a first-pitch strike rate of just 58% this season — lowest in MLB.

Reds pitchers have a strike rate of just 62% this season — tied for lowest in MLB.

Cardinals Pitching Stats & Trends

Opponents have a miss rate of just 22% against Cardinals pitchers this season — tied for lowest in MLB.

Opponents have a groundball rate of 46% against Cardinals pitchers this season — 3rd highest in MLB.

Cardinals pitchers have a strikeout rate of just 18% with runners in scoring position this season — 3rd lowest in MLB.

Cardinals pitchers have allowed an average Exit Velocity of 89.8 MPH (2,697 batted balls) this season — tied for highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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