Reds vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Sep 15

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Sep 15, 2022, 3:30 PM
  • The Cardinals (84-59) are -275 favorites vs the Reds (56-86)
  • Reds starting pitcher: Robert Anderson (0-3), 9.00 ERA
  • Cardinals starting pitcher: Miles Mikolas (11-11), 3.42 ERA
  • Watch the game on MLB Network

The Cincinnati Reds (+220) visit Busch Stadium to take on the St. Louis Cardinals (-275) on Thursday, September 15, 2022. First pitch is scheduled for 7:45pm EDT in St. Louis.

The Cardinals are betting favorites in this MLB matchup, with the run line sitting at -2.5 (+110).

The Reds vs Cardinals Over/Under is 8 total runs for the game.

So far this season, the Reds are 54-86 against the spread (ATS), while the Cardinals are 78-62 ATS.

Reds vs. Cardinals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Reds+2.5 -135O 8 -105+220
Cardinals -2.5 +110U 8 -115-275

Reds vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the will win Thursday‘s matchup with confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Reds and Cardinals and up-to-date player injuries.


Looking for a risk-free bet up to $1,000? Bet now on Cardinals vs Reds and all MLB games with BetMGM


Best Reds Player Prop Bets Today

We’ve highlighted some favorite MLB player prop bets for Reds players for Thursday‘s game, looking at profitable historical betting trends:

  • Donovan Solano has hit the Runs Under in 17 of his last 20 games (+11.70 Units / 29% ROI)
  • Jonathan India has hit the Hits Over in 24 of his last 31 away games (+11.20 Units / 17% ROI)
  • Tyler Stephenson has hit the Runs Under in 17 of his last 20 away games (+10.65 Units / 25% ROI)
  • Joey Votto has hit the Runs Under in 30 of his last 41 away games (+10.30 Units / 14% ROI)
  • Joey Votto has hit the Hits Under in 8 of his last 9 games (+10.10 Units / 110% ROI)

Best Cardinals Player Prop Best Bets Today

And here are some favorite MLB player prop bets for Cardinals players for Thursday‘s game, looking at profitable historical betting trends:

  • Paul Goldschmidt has hit the Total Bases Over in 35 of his last 56 games at home (+16.10 Units / 26% ROI)
  • Tommy Edman has hit the Hits Over in 14 of his last 15 games (+14.80 Units / 54% ROI)
  • Corey Dickerson has hit the Runs Under in 15 of his last 16 games at home (+13.20 Units / 39% ROI)
  • Paul Goldschmidt has hit the Runs Over in 34 of his last 56 games at home (+12.55 Units / 20% ROI)
  • Tommy Edman has hit the Total Bases Over in 16 of his last 20 games (+12.40 Units / 44% ROI)

Cardinals vs Reds Home Run Prop Bets Today

Over Under
Albert Pujols 0.5 +425 0.5 -800
Burleson 0.5 +575 0.5 -1400
Brendan Donovan 0.5 +875 0.5 -5000
Corey Dickerson 0.5 +600 0.5 -1600
Lars Nootbaar 0.5 +600 0.5 -1600

Cardinals vs Reds Total Hits Prop Bets Today

Over Under
Albert Pujols 0.5 -160 0.5 +115
Burleson 0.5 -160 0.5 +115
Brendan Donovan 0.5 -200 0.5 +140
Corey Dickerson 0.5 -275 0.5 +185
Lars Nootbaar 0.5 -120 0.5 -115

Cardinals vs Reds RBI Prop Bets Today

Over Under
Albert Pujols 0.5 +165 0.5 -250
Burleson 0.5 +185 0.5 -275
Brendan Donovan 0.5 +190 0.5 -275
Corey Dickerson 0.5 +155 0.5 -225
Lars Nootbaar 0.5 +230 0.5 -350

Cardinals vs Reds Strikeout Prop Bets Today

Over Under
Miles Mikolas 4.5 -105 4.5 -135
Chase Anderson 2.5 -120 2.5 -115
  • The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 63 of their last 114 games (+12.60 Units / 10% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Total Under in 28 of their last 51 away games (+3.95 Units / 7% ROI)
  • The Cincinnati Reds have hit the Game Total Over in 6 of their last 12 games (+1.70 Units / 13% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Total Over in 61 of their last 120 games (+3.55 Units / 3% ROI)
  • The St. Louis Cardinals have hit the Game Total Over in 5 of their last 7 games (+2.90 Units / 37% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 12 of their last 20 games at home (+2.00 Units / 8% ROI)

Reds Against the Spread (ATS) Record

Against the spread this MLB season, the Reds have gone 64-75 against the Run Line (-16.45 Units / -9.67% ROI).

  • 54-86 when betting on the Moneyline for -19.75 Units / -13.09% ROI
  • 69-67 when betting on the total runs Over for -5.35 Units / -3.46% ROI
  • 67-69 when betting on the total runs Under for -9.4 Units / -6.1% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this MLB season, the Reds have gone 78-62 against the Run Line (+13.25 Units / 7.6% ROI).

  • 81-59 when betting on the Moneyline for +8.1 Units / 4.1% ROI
  • 66-68 when betting on the total runs Over for -9.1 Units / -5.93% ROI
  • 68-66 when betting on the total runs Under for -4.05 Units / -2.65% ROI

Chase Anderson has walked 7 of 26 batters (27%) this month (2 games) — highest in MLB among starting pitchers with at least 5 total IP; League Avg: 7% — 0 Percentile.

Chase Anderson has a strike rate of just 54% (76/140) this month (2 games) — lowest in MLB among starting pitchers with at least 5 total IP; League Avg: 65% — 0 Percentile.

Chase Anderson has thrown at least two strikes in his first three pitches to 44% (11/25) of opposing batters this month (2 games) — 4th lowest in MLB among starting pitchers with at least 5 total IP; League Avg: 65% — second Percentile.

Opponents are hitting just .053 (1-for-19) against Chase Anderson this month (2 games) — best in MLB among starting pitchers with at least 5 total IP; League Avg: .245 — 100th Percentile.

Miles Mikolas: Cardinals Starting Pitcher Stats & Trends

Opponents have a miss rate of just 18% (252/1,370) against Miles Mikolas this season — 4th lowest among qualified SPs in MLB; League Avg: 25% — seventh Percentile.

Miles Mikolas has allowed an average Exit Velocity of just 75.5 MPH on pitches out of the zone since the start of last season (123 balls in play) — 3rd best in MLB among starting pitchers with at least 151 total IP; League Avg: 80.3

Miles Mikolas has walked 5 of 120 batters (4%) with runners in scoring position this season — 2nd best among qualified SPs in MLB; League Avg: 8% — 97th Percentile.

Miles Mikolas has walked 6 of 261 batters (2%) versus the top of the order this season — best among qualified SPs in MLB; League Avg: 7% — 100th Percentile.

Reds Keys to the Game vs. the Cardinals

The Reds are just 19-70 (.213) when scoring 4 or fewer runs this season — 3rd lowest in MLB; League Avg: .296.

The Reds are just 11-66 (.143) when allowing 5 or more runs this season — tied for 6th lowest in MLB; League Avg: .199.

The Reds are just 29-43 (.403) at home this season — tied for 5th lowest in MLB; League Avg: .526.

The Reds are just 8-29 (.216) when their opponents score in the first inning this season — 4th lowest in MLB; League Avg: .337.

Cardinals Keys to the Game vs. the Reds

The Cardinals are 14-4 (.778) when tied entering the 8th inning this season — best in MLB; League Avg: .500.

The Cardinals are 8-47 (.145) when trailing entering the 7th inning this season — 8th best in MLB; League Avg: .117.

The Cardinals are 70-19 (.787) when allowing 4 or fewer runs this season — 5th best in MLB; League Avg: .704.

The Cardinals are 13-9 (.591) when tied entering the 7th inning this season — 6th best in MLB; League Avg: .500.

Reds hitters have 733 strikeouts in 3,053 PA’s (24%) against LHP since the start of last season — 5th highest in MLB; League Avg: 22%.

The Reds are batting just .314 on the first pitch of at-bats this season — tied for 2nd lowest in MLB; League Avg: .336.

Reds hitters are slugging just .354 on the road this season — 3rd lowest in MLB; League Avg: .391.

Reds hitters have an OBP of just .299 (654 PA’s) when facing the starting pitcher for the 3rd time in a game this season — 3rd lowest in MLB; League Avg: .324.

Cardinals hitters have 245 extra-base hits out of 567 total hits (43%) against LHP since the start of last season — best in MLB; League Avg: 35%.

Cardinals hitters are slugging .472 against LHP since the start of last season — best in MLB; League Avg: .408.

Cardinals hitters are slugging .721 against LHP this month (7 games) — best in MLB; League Avg: .418.

Cardinals hitters have an OPS of 1.136 (53 PA’s) against LHP this month (7 games) — best in MLB; League Avg: .728.

Reds pitchers have walked 527 of 5,469 batters (10%) this season — highest in MLB; League Avg: 8%.

Reds pitchers have walked 1,357 of 13,793 batters (10%) since the start of 2020 — tied for highest in MLB; League Avg: 9%.

Reds pitchers have walked 111 of 1,251 batters (9%) when facing the leadoff batter in the inning this season — tied for 3rd highest in MLB; League Avg: 7%.

Reds pitchers have walked 13 of 114 batters (11%) when facing the leadoff batter in the inning this month (13 games) — 2nd highest in MLB; League Avg: 7%.

Opponents have a groundball rate of 48% against Cardinals pitchers this season — 2nd highest in MLB; League Avg: 43%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the start of last season — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers have a strikeout rate of just 19% this season — 3rd lowest in MLB; League Avg: 22%.

Opponents have a miss rate of just 22% against Cardinals pitchers this season — lowest in MLB; League Avg: 25%.

Cardinals vs. Reds Injuries Tonight That May Affect Prop Bets 

  • Dylan Carlson (Cardinals): Thumb, D10
  • Alexander Reyes (Cardinals): Shoulder, D60
  • Steven Matz (Cardinals): Knee, D15
  • Drew VerHagen (Cardinals): Hip, D60
  • Antonio Santillan (Reds): Back, D60
  • Lucas Sims (Reds): Back, D60
  • Christian Greene (Reds): Shoulder, D15
  • Connor Overton (Reds): Back, D60
  • Robert Dugger (Reds): Shoulder, D15
  • Jeffrey Hoffman (Reds): Forearm, D60
  • Aramis Garcia (Reds): Finger, D60
  • Tyler Stephenson (Reds): Clavicle, D60
  • Justin Wilson (Reds): Elbow, D60
  • Douglas Ashcraft (Reds): Biceps, D15
  • Vladimir Gutierrez (Reds): Forearm, D60
  • Daniel Duarte (Reds): Elbow, D60
  • Joseph Votto (Reds): Rotator Cuff, D60
  • Michael Moustakas (Reds): Calf, D60
  • Tejay Antone (Reds): Elbow, D60

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.