Reds vs Nationals Prediction, Odds & Player Prop Bets Today – MLB, Jul 21

(AP Photo/Terrance Williams)
  • The Reds are -135 favorites vs the Nationals
  • Reds vs Nationals Over / Under today: 9 Runs
  • Reds / Nationals TV Channel: FDOH | MASN

The Cincinnati Reds (-120) visit Nationals Park to take on the Washington Nationals (+100) on Monday, July 21, 2025. First pitch is scheduled for 6:45pm EDT in Washington, DC.

This season, the Reds are 52-48 against the spread (ATS), while the Nationals are 48-51 ATS.

Reds vs Nationals Starting Pitchers Today:

  • Reds starting pitcher: Brady Singer 7-7, 4.35 ERA
  • Nationals starting pitcher: Jake Irvin 7-5, 4.64 ERA

Reds vs. Nationals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Reds-1.5 +135O 9 -115-120
Nationals +1.5 -165U 9 -105+100

Reds vs Nationals Prediction for Today’s Game

Based on recent trends the model predicts the Reds will win Monday‘s MLB game with 55.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Reds players for Monday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Bets Today:

  • Noelvi Marte has hit the Home Runs Over in 3 of his last 8 games (+11.80 Units / 148% ROI)
  • Elly De La Cruz has hit the RBIs Over in 10 of his last 20 away games (+8.05 Units / 40% ROI)
  • TJ Friedl has hit the Hits Under in 11 of his last 20 games (+7.85 Units / 39% ROI)
  • Elly De La Cruz has hit the Hits Runs and RBIs Over in 17 of his last 25 away games (+7.40 Units / 25% ROI)
  • Austin Hays has hit the Singles Under in 14 of his last 20 games (+7.00 Units / 28% ROI)

And here are some favorite MLB player prop bets for Nationals players for Monday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Best Bets Today:

  • James Wood has hit the Runs Under in 19 of his last 25 games at home (+12.25 Units / 37% ROI)
  • Riley Adams has hit the Home Runs Over in 2 of his last 5 games (+11.40 Units / 228% ROI)
  • Jacob Young has hit the Hits Runs and RBIs Under in 13 of his last 15 games at home (+11.25 Units / 52% ROI)
  • Daylen Lile has hit the Hits Over in 16 of his last 20 games (+8.85 Units / 26% ROI)
  • Daylen Lile has hit the Total Bases Over in 15 of his last 20 games (+8.45 Units / 28% ROI)
  • The Cincinnati Reds have hit the Game Total Under in 47 of their last 77 games (+16.15 Units / 19% ROI)
  • The Cincinnati Reds have hit the Moneyline in 22 of their last 37 games (+7.45 Units / 16% ROI)
  • The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 6 of their last 7 away games (+4.60 Units / 54% ROI)
  • The Cincinnati Reds have covered the Run Line in 6 of their last 8 games (+3.80 Units / 35% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in 8 of their last 12 games (+3.70 Units / 26% ROI)
  • The Washington Nationals have hit the Team Total Under in 50 of their last 83 games (+13.59 Units / 14% ROI)
  • The Washington Nationals have hit the Game Total Over in 18 of their last 24 games (+13.50 Units / 51% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Team Total Under in 43 of their last 73 games (+10.32 Units / 12% ROI)

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 53-46 against the Run Line (-0.68 Units / -0.5% ROI).

  • 52-48 when betting on the Moneyline for +0.45 Units / 0.37% ROI
  • 40-57 when betting on the total runs Over for -22.04 Units / -20.14% ROI
  • 57-40 when betting on the total runs Under for +13.1 Units / 11.84% ROI

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 48-51 against the Run Line (-13.1 Units / -10.2% ROI).

  • 39-60 when betting on the Moneyline for -13.57 Units / -12.84% ROI
  • 52-43 when betting on the total runs Over for +4.8 Units / 4.4% ROI
  • 43-52 when betting on the total runs Under for -14.05 Units / -12.92% ROI

Nationals vs Reds Home Run Prop Bets Today

Over Under
Elly De La Cruz (CIN) 0.5 +450 0.5 -625
James Wood (WAS) 0.5 +475 0.5 -650
Josh Bell (WAS) 0.5 +500 0.5 -750
Austin Hays (CIN) 0.5 +575 0.5 -900
CJ Abrams (WAS) 0.5 +575 0.5 -900

Nationals vs Reds Total Hits Prop Bets Today

Over Under
Austin Hays (CIN) 0.5 -250 0.5 +180
Matt McLain (CIN) 0.5 -235 0.5 +180
Gavin Lux (CIN) 0.5 -225 0.5 +170
Spencer Steer (CIN) 0.5 -210 0.5 +155
Tyler Stephenson (CIN) 0.5 -200 0.5 +150

Nationals vs Reds RBI Prop Bets Today

Over Under
Austin Hays (CIN) 0.5 +125 0.5 -165
Elly De La Cruz (CIN) 0.5 +140 0.5 -185
Josh Bell (WAS) 0.5 +140 0.5 -190
Luis Garcia (WAS) 0.5 +140 0.5 -190
CJ Abrams (WAS) 0.5 +170 0.5 -225

Nationals vs Reds Strikeout Prop Bets Today

Over Under
Brady Singer (CIN) 4.5 -160 4.5 +125
Jake Irvin (WAS) 4.5 -115 4.5 -115

Brady Singer has walked 10% of batters when going through the lineup the first time in a game since last season — 2nd highest among qualified SPs in MLB; League Avg: 7% — fourth Percentile.

Brady Singer has thrown inside pitches 49% of the time (478/978) vs left-handed batters this season — highest among qualified SPs in MLB; League Avg: 31% — 100th Percentile.

Brady Singer has a strike rate of just 60% (438/732) against right-handed batters this season — lowest among qualified SPs in MLB; League Avg: 65% — first Percentile.

Brady Singer has allowed a slugging percentage of .658 (25 Total Bases / 38 ABs) on low fastballs this season — 2nd highest among qualified SPs in MLB; League Avg: .412 — third Percentile.

Nationals Starting Pitcher Stats & Trends

Jake Irvin has thrown 59% of his pitches in the strike zone (474/804) against right-handed batters this season — best among qualified SPs in MLB; League Avg: 51% — 100th Percentile.

Opponents have a miss rate of just 17% (152/875) against Jake Irvin this season — 3rd lowest among qualified SPs in MLB; League Avg: 25% — fourth Percentile.

Jake Irvin has thrown 60% of his pitches in the strike zone (219/364) with runners in scoring position this season — best among qualified SPs in MLB; League Avg: 49% — 100th Percentile.

Jake Irvin has allowed an OPS of 1.040 (103 PA’s) with runners in scoring position this season — highest among qualified SPs in MLB; League Avg: .709 — first Percentile.

Reds Keys to the Game vs. the Nationals

The Reds were just 5-16 (.238) when tied entering the 8th inning in the 2024 season — lowest in MLB; League Avg: .500.

The Reds are just 8-22 (.267) when tied entering the 8th inning since last season — 2nd lowest in MLB; League Avg: .500.

The Reds are just 16-33 (.327) when tied entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .500.

The Reds are just 15-23 (.395) when tied entering the 7th inning since last season — tied for 4th lowest in MLB; League Avg: .499.

Nationals Keys to the Game vs. the Reds

The Nationals are just 18-30 (.367) at home this season — 2nd lowest in MLB; League Avg: .547.

The Nationals are just 38-60 (.384) this season — 3rd lowest in MLB; League Avg: .500.

The Nationals are just 37-52 (.411) when allowing 5 or more extra base hits this season — 3rd lowest in MLB; League Avg: .533.

The Nationals are just 32-2 (.914) when leading entering the 9th inning this season — 4th lowest in MLB; League Avg: .956.

Reds hitters have chased 35% of pitches out of the zone with two-strikes this season — lowest in MLB; League Avg: 38%.

Reds hitters are slugging just .360 against LHP since last season — 3rd lowest in MLB; League Avg: .393.

Reds hitters are slugging .923 on the first pitch of at-bats over the last 14 days — 2nd best in MLB; League Avg: .582.

The Reds batted just .116 on pitches out of the zone in the 2024 season — lowest in MLB; League Avg: .150.

Nationals hitters have put just 32% of balls in play to the left side of the field this season — lowest in MLB; League Avg: 38%.

The Nationals are batting just .133 when facing the starting pitcher for the 3rd time in a game over the last 14 days — 2nd lowest in MLB; League Avg: .250.

The Nationals batted just .226 when facing the starting pitcher for the 3rd time in a game in the 2024 season — 2nd lowest in MLB; League Avg: .263.

The Nationals have a winning percentage of just 39% at home this season — 2nd lowest in MLB; League Avg: 55%.

Reds pitchers have walked 15% of batters when facing the leadoff batter in the inning over the last 14 days — highest in MLB; League Avg: 8%.

Opponents have a groundball rate of just 39% against Reds pitchers since last season — lowest in MLB; League Avg: 43%.

Opponents had a groundball rate of just 39% against Reds pitchers in the 2024 season — lowest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 39% against Reds pitchers this season — 3rd lowest in MLB; League Avg: 42%.

Nationals pitchers have a strikeout rate of just 34% with two-strikes this month (15 games) — lowest in MLB; League Avg: 42%.

The Nationals have allowed 1.97 runs per game (195/99) in late innings this season — highest in MLB; League Avg: 1.33.

Nationals pitchers have a strikeout rate of just 34% with two-strikes over the last 14 days — 2nd lowest in MLB; League Avg: 42%.

Nationals pitchers have an ERA of 5.21 (871.2 IP) this season — 3rd highest in MLB; League Avg: 4.09.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.