Reds vs Twins Prediction, Odds & Player Prop Bets Today – MLB, Apr 17

Minnesota Twins' Royce Lewis reacts towards the dugout after a solo home run during the first inning of Game 4 of a baseball AL Division Series against the Houston Astros, Wednesday, Oct. 11, 2023, in Minneapolis.
AP Photo/Bruce Kluckhohn
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  • The Twins are -180 favorites vs the Reds
  • Reds vs Twins Over / Under today: 7.5 Runs
  • Reds / Twins TV Channel: TWTV | RDTV

The Cincinnati Reds (+145) visit Target Field to take on the Minnesota Twins (-180) on April 17, 2026. First pitch is scheduled for 8:10 pm in Minneapolis, MN.

This season, the Reds are 11-8 against the spread (ATS), while the Twins are 12-7 ATS.

Reds vs Twins Starting Pitchers Today:

  • Reds starting pitcher: Brandon Williamson 1-1, 5.29 ERA
  • Twins starting pitcher: Joe Ryan 2-1, 3.86 ERA

Reds vs. Twins Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Reds+1.5 -150O 7.5 -105+145
Twins -1.5 +125U 7.5 -115-180

Reds vs Twins Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Friday‘s MLB game with 62.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Reds players for Friday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Bets Today:

  • Ke’Bryan Hayes has hit the Hits Runs and RBIs Under in 17 of his last 20 games (+14.75 Units / 53% ROI)
  • Ke’Bryan Hayes has hit the Hits Under in 16 of his last 20 games (+14.65 Units / 73% ROI)
  • Ke’Bryan Hayes has hit the Total Bases Under in 16 of his last 20 games (+14.30 Units / 71% ROI)
  • Sal Stewart has hit the Home Runs Over in 4 of his last 8 games (+13.55 Units / 169% ROI)
  • Elly De La Cruz has hit the Runs Over in 12 of his last 15 games (+11.50 Units / 76% ROI)

And here are some favorite MLB player prop bets for Twins players for Friday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Best Bets Today:

  • Ryan Kreidler has hit the Home Runs Over in 2 of his last 4 games (+23.00 Units / 575% ROI)
  • Luke Keaschall has hit the Hits Over in 17 of his last 20 games at home (+10.35 Units / 24% ROI)
  • Austin Martin has hit the Runs Over in his last 6 games (+9.20 Units / 153% ROI)
  • Austin Martin has hit the Walks Over in 7 of his last 10 games (+8.15 Units / 81% ROI)
  • Brooks Lee has hit the Hits Runs and RBIs Over in 8 of his last 9 games (+8.05 Units / 76% ROI)
  • The Cincinnati Reds have hit the Game Total Under in 27 of their last 45 away games (+9.60 Units / 19% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in 12 of their last 17 games (+6.70 Units / 34% ROI)
  • The Cincinnati Reds have hit the Team Total Under in 24 of their last 40 games (+5.45 Units / 11% ROI)
  • The Cincinnati Reds have hit the Moneyline in 8 of their last 13 away games (+4.50 Units / 34% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Moneyline in 3 of their last 5 games (+2.00 Units / 35% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Moneyline in 14 of their last 25 games (+10.40 Units / 39% ROI)
  • The Minnesota Twins have hit the Team Total Over in 14 of their last 18 games (+9.35 Units / 43% ROI)
  • The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 17 of their last 25 games (+8.45 Units / 29% ROI)
  • The Minnesota Twins have hit the Moneyline in 10 of their last 14 games (+7.80 Units / 54% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Over in 8 of their last 10 games (+5.70 Units / 45% ROI)

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 11-8 against the Run Line (+0.35 Units / 1.21% ROI).

  • 11-8 when betting on the Moneyline for +3.3 Units / 15.79% ROI
  • 10-8 when betting on the total runs Over for +1.2 Units / 5.74% ROI
  • 8-10 when betting on the total runs Under for -3 Units / -14.35% ROI

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 12-7 against the Run Line (+2.45 Units / 8.81% ROI).

  • 11-8 when betting on the Moneyline for +5.1 Units / 26.02% ROI
  • 10-8 when betting on the total runs Over for +1.15 Units / 5.5% ROI
  • 8-10 when betting on the total runs Under for -3.05 Units / -14.59% ROI

Twins vs Reds Home Run Prop Bets Today

Yes
Byron Buxton +340
Eugenio Suarez +475
Matt Wallner +500
Ryan Jeffers +500
Sal Stewart +525

Twins vs Reds Total Hits Prop Bets Today

Over Under
Byron Buxton 0.5 -225 0.5 +165
Luke Keaschall 0.5 -210 0.5 +150
Austin Martin 0.5 -190 0.5 +140
Elly De La Cruz 0.5 -190 0.5 +140
Sal Stewart 0.5 -185 0.5 +135

Twins vs Reds Strikeout Prop Bets Today

Over Under
TJ Friedl 0.5 -175 0.5 +130
Victor Caratini 0.5 -165 0.5 +125
Ke'Bryan Hayes 0.5 -160 0.5 +120
Brandon Williamson 3.5 -150 3.5 +110
Ryan Jeffers 0.5 -140 0.5 +105

Reds Keys to the Game vs. the Twins

The Reds are 5-2 (.714) on the road this season — 2nd best in MLB; League Avg: .435.

The Reds are 10-2 (.833) when allowing 4 or fewer runs this season — tied for 4th best in MLB; League Avg: .712.

The Reds are just 8-56 (.125) when allowing 5 or more runs since the 2025 season — 3rd lowest in MLB; League Avg: .206.

The Reds are just 14-27 (.341) when tied entering the 8th inning since the 2024 season — 2nd lowest in MLB; League Avg: .500.

Twins Keys to the Game vs. the Reds

The Twins are just 6-21 (.222) when tied entering the 7th inning since the 2025 season — lowest in MLB; League Avg: .500.

The Twins were just 5-19 (.208) when tied entering the 7th inning in the 2025 season — lowest in MLB; League Avg: .500.

The Twins were just 20-76 (.208) when they scored 4 or fewer runs in the 2025 season — 3rd lowest in MLB; League Avg: .286.

The Twins are just 0-7 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .050.

Reds hitters have a swing rate of just 39% in lefty-lefty matchups since the 2025 season — lowest in MLB.

The Reds are batting just .167 with runners on base this season — lowest in MLB.

Reds hitters are slugging just .284 with runners on base this season — lowest in MLB.

Reds hitters slugged just .353 against LHP in the 2025 season — tied for 3rd lowest in MLB.

Twins hitters are slugging just .163 on pitches out of the zone since the 2025 season — 2nd lowest in MLB.

Twins hitters slugged just .163 on pitches out of the zone in the 2025 season — 2nd lowest in MLB.

The Twins batted just .226 when facing the starting pitcher for the 3rd time in a game in the 2025 season — lowest in MLB.

The Twins batted just .126 on pitches out of the zone in the 2025 season — 2nd lowest in MLB.

Opponents have a groundball rate of just 40% against Reds pitchers since the 2025 season — 3rd lowest in MLB.

Opponents have a groundball rate of just 37% against Reds pitchers over the past seven days (6 games) — 2nd lowest in MLB.

Reds pitchers have a first-pitch strike rate of just 56% this season — lowest in MLB.

Opponents have a groundball rate of just 39% against Reds pitchers since the 2024 season — lowest in MLB.

Opponents have a groundball rate of just 39% against Twins pitchers this season — tied for lowest in MLB.

Opponents had a groundball rate of just 39% against Twins pitchers in the 2025 season — 2nd lowest in MLB.

Opponents have a groundball rate of just 39% against Twins pitchers since the 2025 season — 2nd lowest in MLB.

Opponents have a miss rate of just 22% against Twins pitchers this season — 3rd lowest in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.