San Diego Padres vs Cincinnati Reds Prediction, Odds & Player Prop Bets Today – MLB, Jun 27

  • The San Diego Padres are -140 favorites vs the Cincinnati Reds
  • San Diego Padres vs Cincinnati Reds Over / Under today: 9 Runs
  • San Diego Padres / Cincinnati Reds TV Channel: FDOH | PDTV

The San Diego Padres (-135) visit Great American Ball Park to take on the Cincinnati Reds (+115) on Friday, June 27, 2025. First pitch is scheduled for 7:10pm EDT in Cincinnati, OH.

This season, the San Diego Padres are 44-36 against the spread (ATS), while the Cincinnati Reds are 44-36 ATS.

San Diego Padres vs Cincinnati Reds Starting Pitchers Today:

  • San Diego Padres starting pitcher: , ERA
  • Cincinnati Reds starting pitcher: , ERA

San Diego Padres vs. Cincinnati Reds Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
San Diego Padres-1.5 +125O 9 +100-135
Cincinnati Reds +1.5 -150U 9 -120+115

San Diego Padres vs Cincinnati Reds Prediction for Today’s Game

Based on recent trends the model predicts the will win Friday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for San Diego Padres players for Friday‘s game, looking at profitable historical betting trends:

Best San Diego Padres Player Prop Bets Today:

  • Fernando Tatis Jr. has hit the Hits Under in 19 of his last 25 games (+12.70 Units / 27% ROI)
  • Luis Arraez has hit the Singles Under in 12 of his last 20 away games (+11.30 Units / 56% ROI)
  • Fernando Tatis Jr. has hit the RBIs Under in 21 of his last 25 games (+11.30 Units / 19% ROI)
  • Dylan Cease has hit the Earned Runs Over in 18 of his last 25 games (+11.00 Units / 36% ROI)
  • Gavin Sheets has hit the Total Bases Over in 13 of his last 15 games (+10.05 Units / 42% ROI)

And here are some favorite MLB player prop bets for Cincinnati Reds players for Friday‘s game, looking at profitable historical betting trends:

Best Cincinnati Reds Player Prop Best Bets Today:

  • Elly De La Cruz has hit the Runs Over in 17 of his last 25 games (+10.55 Units / 40% ROI)
  • Elly De La Cruz has hit the Total Bases Over in 16 of his last 25 games (+9.55 Units / 35% ROI)
  • Gavin Lux has hit the Home Runs Over in 2 of his last 4 games at home (+9.00 Units / 225% ROI)
  • TJ Friedl has hit the Walks Under in his last 9 games (+9.00 Units / 46% ROI)
  • Elly De La Cruz has hit the RBIs Under in 9 of his last 10 games at home (+7.65 Units / 40% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 25 of their last 38 games (+11.10 Units / 25% ROI)
  • The San Diego Padres have hit the Game Total Under in 39 of their last 66 games (+10.40 Units / 14% ROI)
  • The San Diego Padres have hit the Team Total Under in 24 of their last 37 away games (+9.30 Units / 22% ROI)
  • The San Diego Padres have covered the Run Line in 10 of their last 15 away games (+3.70 Units / 17% ROI)
  • The San Diego Padres have hit the Moneyline in 5 of their last 7 games (+2.70 Units / 26% ROI)
  • The Cincinnati Reds have hit the Game Total Under in 36 of their last 58 games (+11.75 Units / 18% ROI)
  • The Cincinnati Reds have hit the Moneyline in 12 of their last 18 games (+7.65 Units / 40% ROI)
  • The Cincinnati Reds have covered the Run Line in 12 of their last 19 games at home (+6.15 Units / 24% ROI)
  • The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 39 of their last 71 games (+3.80 Units / 5% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Over in 8 of their last 12 games (+3.35 Units / 24% ROI)

San Diego Padres Against the Spread (ATS) Record

Against the spread this season, the San Diego Padres are 42-38 against the Run Line (-0.25 Units / -0.24% ROI).

  • 44-36 when betting on the Moneyline for +2.25 Units / 2.1% ROI
  • 33-45 when betting on the total runs Over for -16.05 Units / -18.32% ROI
  • 45-33 when betting on the total runs Under for +8.55 Units / 9.65% ROI

Cincinnati Reds Against the Spread (ATS) Record

Against the spread this season, the Cincinnati Reds are 44-36 against the Run Line (+1.4 Units / 1.27% ROI).

  • 42-39 when betting on the Moneyline for +0.65 Units / 0.68% ROI
  • 34-46 when betting on the total runs Over for -15.85 Units / -17.92% ROI
  • 46-34 when betting on the total runs Under for +8.7 Units / 9.69% ROI

Cincinnati Reds vs San Diego Padres Home Run Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +260 0.5 -325
Fernando Tatis Jr. (SD) 0.5 +270 0.5 -350
Jackson Merrill (SD) 0.5 +280 0.5 -350
Christian Encarnacion-Strand (CIN) 0.5 +360 0.5 -500
Elly De La Cruz (CIN) 0.5 +425 0.5 -600

Cincinnati Reds vs San Diego Padres Total Hits Prop Bets Today

Over Under
Xander Bogaerts (SD) 0.5 -235 0.5 +175
Jose Iglesias (SD) 0.5 -220 0.5 +165
Elly De La Cruz (CIN) 0.5 -200 0.5 +150
Christian Encarnacion-Strand (CIN) 0.5 -190 0.5 +145
Gavin Sheets (SD) 0.5 -185 0.5 +140

Cincinnati Reds vs San Diego Padres RBI Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +105 0.5 -140
Jackson Merrill (SD) 0.5 +130 0.5 -165
Manny Machado (SD) 0.5 +135 0.5 -175
Tyler Stephenson (CIN) 0.5 +160 0.5 -220
Gavin Sheets (SD) 0.5 +165 0.5 -220

Cincinnati Reds vs San Diego Padres Strikeout Prop Bets Today

Over Under
Dylan Cease (SD) 6.5 -150 6.5 +110
Nick Martinez (CIN) 3.5 +115 3.5 -150

starting pitcher – away

Cincinnati Reds Starting Pitcher Stats & Trends

starting pitcher – home

San Diego Padres Keys to the Game vs. the Cincinnati Reds

keys to the game – away

Cincinnati Reds Keys to the Game vs. the San Diego Padres

keys to the game – home

team hitters – away

team hitters – home

team pitchers – away

team pitchers – home

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.