Seattle Mariners vs Chicago Cubs Prediction, Odds & Player Prop Bets Today – MLB, Jun 22

  • The Seattle Mariners are -115 favorites vs the Chicago Cubs
  • Seattle Mariners vs Chicago Cubs Over / Under today: 11.5 Runs
  • Seattle Mariners / Chicago Cubs TV Channel: MARQ | RTNW

The Seattle Mariners (-125) visit Wrigley Field to take on the Chicago Cubs (+105) on Sunday, June 22, 2025. First pitch is scheduled for 2:20pm EDT in Chicago, IL.

This season, the Seattle Mariners are 38-37 against the spread (ATS), while the Chicago Cubs are 38-38 ATS.

Seattle Mariners vs Chicago Cubs Starting Pitchers Today:

  • Seattle Mariners starting pitcher: , ERA
  • Chicago Cubs starting pitcher: , ERA

Seattle Mariners vs. Chicago Cubs Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Seattle Mariners-1.5 +130O 11.5 -118-125
Chicago Cubs +1.5 -155U 11.5 -102+105

Seattle Mariners vs Chicago Cubs Prediction for Today’s Game

Based on recent trends the model predicts the will win Sunday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Seattle Mariners players for Sunday‘s game, looking at profitable historical betting trends:

Best Seattle Mariners Player Prop Bets Today:

  • Julio Rodriguez has hit the Hits Over in 17 of his last 25 away games (+14.70 Units / 41% ROI)
  • Logan Gilbert has hit the Pitching Outs Under in 12 of his last 15 games (+9.95 Units / 46% ROI)
  • Logan Gilbert has hit the Hits Allowed Under in 18 of his last 25 games (+9.35 Units / 29% ROI)
  • Randy Arozarena has hit the RBIs Under in 13 of his last 15 away games (+8.60 Units / 26% ROI)
  • Randy Arozarena has hit the Total Bases Over in 17 of his last 25 away games (+8.00 Units / 24% ROI)

And here are some favorite MLB player prop bets for Chicago Cubs players for Sunday‘s game, looking at profitable historical betting trends:

Best Chicago Cubs Player Prop Best Bets Today:

  • Seiya Suzuki has hit the Singles Under in 21 of his last 25 games at home (+15.65 Units / 48% ROI)
  • Pete Crow-Armstrong has hit the Home Runs Over in 4 of his last 8 games (+14.80 Units / 185% ROI)
  • Dansby Swanson has hit the Runs Under in 19 of his last 25 games (+9.85 Units / 23% ROI)
  • Michael Busch has hit the Hits Over in 18 of his last 25 games (+8.15 Units / 19% ROI)
  • Pete Crow-Armstrong has hit the Total Bases Over in 14 of his last 20 games (+8.00 Units / 31% ROI)
  • The Seattle Mariners have hit the Game Total Over in 36 of their last 63 games (+8.55 Units / 12% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Over in 39 of their last 69 games (+6.40 Units / 8% ROI)
  • The Seattle Mariners have hit the Team Total Under in 15 of their last 25 games (+4.35 Units / 16% ROI)
  • The Seattle Mariners have hit the Moneyline in 18 of their last 32 away games (+3.75 Units / 10% ROI)
  • The Seattle Mariners have covered the Run Line in 3 of their last 6 games (+0.10 Units / 1% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 39 of their last 74 games (+13.70 Units / 13% ROI)
  • The Chicago Cubs have hit the Moneyline in 44 of their last 70 games (+12.25 Units / 11% ROI)
  • The Chicago Cubs have hit the Game Total Under in 15 of their last 23 games (+8.35 Units / 33% ROI)
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 41 of their last 72 games (+6.85 Units / 8% ROI)
  • The Chicago Cubs have hit the Team Total Under in 15 of their last 23 games (+6.15 Units / 23% ROI)

Seattle Mariners Against the Spread (ATS) Record

Against the spread this season, the Seattle Mariners are 33-42 against the Run Line (-9.65 Units / -10.35% ROI).

  • 38-37 when betting on the Moneyline for -8.6 Units / -8.66% ROI
  • 39-32 when betting on the total runs Over for +3.85 Units / 4.68% ROI
  • 32-39 when betting on the total runs Under for -11.02 Units / -13.29% ROI

Chicago Cubs Against the Spread (ATS) Record

Against the spread this season, the Chicago Cubs are 38-38 against the Run Line (+0.87 Units / 0.95% ROI).

  • 46-30 when betting on the Moneyline for +10.15 Units / 9.01% ROI
  • 38-33 when betting on the total runs Over for +2.25 Units / 2.72% ROI
  • 33-38 when betting on the total runs Under for -9.05 Units / -10.71% ROI

Chicago Cubs vs Seattle Mariners Home Run Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +155 0.5 -190
Kyle Tucker (CHI) 0.5 +230 0.5 -295
Luke Raley (SEA) 0.5 +250 0.5 -325
Pete Crow-Armstrong (CHC) 0.5 +260 0.5 -325
Seiya Suzuki (CHC) 0.5 +270 0.5 -350

Chicago Cubs vs Seattle Mariners Total Hits Prop Bets Today

Over Under
Ian Happ (CHC) 0.5 -275 0.5 +195
Seiya Suzuki (CHC) 0.5 -250 0.5 +195
Randy Arozarena (SEA) 0.5 -250 0.5 +185
Dominic Canzone (SEA) 0.5 -250 0.5 +180
Luke Raley (SEA) 0.5 -225 0.5 +170

Chicago Cubs vs Seattle Mariners RBI Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 -155 0.5 +120
Jorge Polanco (SEA) 0.5 +105 0.5 -135
Pete Crow-Armstrong (CHC) 0.5 +110 0.5 -145
Kyle Tucker (CHI) 0.5 +115 0.5 -150
Seiya Suzuki (CHC) 0.5 +120 0.5 -155

Chicago Cubs vs Seattle Mariners Strikeout Prop Bets Today

Over Under
Colin Rea (CHC) 4.5 +100 4.5 -135
Logan Gilbert (SEA) 6.5 +105 6.5 -135

starting pitcher – away

Chicago Cubs Starting Pitcher Stats & Trends

starting pitcher – home

Seattle Mariners Keys to the Game vs. the Chicago Cubs

keys to the game – away

Chicago Cubs Keys to the Game vs. the Seattle Mariners

keys to the game – home

team hitters – away

team hitters – home

team pitchers – away

team pitchers – home

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.