- The St. Louis Cardinals are -125 favorites vs the Cleveland Guardians
- St. Louis Cardinals vs Cleveland Guardians Over / Under today: 8.5 Runs
- St. Louis Cardinals / Cleveland Guardians TV Channel: ATV
The St. Louis Cardinals (-120) visit Progressive Field to take on the Cleveland Guardians (+100) on Friday, June 27, 2025. First pitch is scheduled for 7:10pm EDT in Cleveland, OH.
This season, the St. Louis Cardinals are 44-38 against the spread (ATS), while the Cleveland Guardians are 41-37 ATS.
St. Louis Cardinals vs Cleveland Guardians Starting Pitchers Today:
- St. Louis Cardinals starting pitcher: , ERA
- Cleveland Guardians starting pitcher: , ERA
St. Louis Cardinals vs. Cleveland Guardians Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| St. Louis Cardinals | -1.5 +140 | O 8.5 -105 | -120 |
| Cleveland Guardians | +1.5 -170 | U 8.5 -115 | +100 |
St. Louis Cardinals vs Cleveland Guardians Prediction for Today’s Game
Based on recent trends the model predicts the will win Friday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for St. Louis Cardinals players for Friday‘s game, looking at profitable historical betting trends:
Best St. Louis Cardinals Player Prop Bets Today:
- Alec Burleson has hit the Total Bases Over in 20 of his last 25 games (+17.55 Units / 57% ROI)
- Alec Burleson has hit the Home Runs Over in 4 of his last 10 games (+12.50 Units / 125% ROI)
- Willson Contreras has hit the RBIs Over in 14 of his last 25 games (+10.15 Units / 41% ROI)
- Sonny Gray has hit the Walks Allowed Under in 14 of his last 20 games (+8.80 Units / 38% ROI)
- Alec Burleson has hit the Hits Over in 8 of his last 9 away games (+7.95 Units / 50% ROI)
And here are some favorite MLB player prop bets for Cleveland Guardians players for Friday‘s game, looking at profitable historical betting trends:
Best Cleveland Guardians Player Prop Best Bets Today:
- Lane Thomas has hit the Home Runs Over in 3 of his last 4 games at home (+16.65 Units / 416% ROI)
- Jose Ramirez has hit the Singles Over in 18 of his last 25 games at home (+11.65 Units / 43% ROI)
- Jose Ramirez has hit the Runs Under in his last 10 games (+10.05 Units / 74% ROI)
- Steven Kwan has hit the Hits Under in 15 of his last 25 games (+9.80 Units / 27% ROI)
- Bo Naylor has hit the Total Bases Under in 12 of his last 15 games at home (+9.40 Units / 57% ROI)
St. Louis Cardinals Best Bets Today:
- The St. Louis Cardinals have covered the Run Line in 18 of their last 25 away games (+12.35 Units / 37% ROI)
- The St. Louis Cardinals have hit the Moneyline in 35 of their last 59 games (+10.85 Units / 16% ROI)
- The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 21 of their last 33 games (+7.15 Units / 18% ROI)
- The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 16 of their last 25 away games (+6.95 Units / 24% ROI)
- The St. Louis Cardinals have hit the Team Total Over in 46 of their last 82 games (+6.92 Units / 7% ROI)
Cleveland Guardians Best Bets Today:
- The Cleveland Guardians have hit the Game Total Under in 27 of their last 42 games (+12.70 Units / 27% ROI)
- The Cleveland Guardians have hit the Team Total Under in 45 of their last 76 games (+10.84 Units / 12% ROI)
- The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 18 of their last 26 games at home (+9.50 Units / 30% ROI)
- The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 9 of their last 13 games (+4.50 Units / 29% ROI)
- The Cleveland Guardians have hit the Moneyline in 37 of their last 70 games (+4.50 Units / 6% ROI)
St. Louis Cardinals Against the Spread (ATS) Record
Against the spread this season, the St. Louis Cardinals are 45-37 against the Run Line (+2.7 Units / 2.42% ROI).
- 44-38 when betting on the Moneyline for +5.2 Units / 5.48% ROI
- 43-35 when betting on the total runs Over for +4.5 Units / 4.98% ROI
- 35-43 when betting on the total runs Under for -12.25 Units / -13.59% ROI
Cleveland Guardians Against the Spread (ATS) Record
Against the spread this season, the Cleveland Guardians are 41-37 against the Run Line (-2.1 Units / -1.93% ROI).
- 40-39 when betting on the Moneyline for +1.35 Units / 1.48% ROI
- 33-42 when betting on the total runs Over for -12 Units / -14.01% ROI
- 42-33 when betting on the total runs Under for +5.8 Units / 6.58% ROI
Cleveland Guardians vs St. Louis Cardinals Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Alec Burleson (STL) | 0.5 +340 | 0.5 -450 |
| Lars Nootbaar (STL) | 0.5 +360 | 0.5 -500 |
| Nolan Gorman (STL) | 0.5 +425 | 0.5 -600 |
| Willson Contreras (STL) | 0.5 +450 | 0.5 -625 |
| Kyle Manzardo (CLE) | 0.5 +450 | 0.5 -625 |
Cleveland Guardians vs St. Louis Cardinals Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Brendan Donovan (STL) | 0.5 -275 | 0.5 +190 |
| Steven Kwan (CLE) | 0.5 -235 | 0.5 +170 |
| Willson Contreras (STL) | 0.5 -225 | 0.5 +175 |
| Nolan Arenado (STL) | 0.5 -210 | 0.5 +160 |
| Lars Nootbaar (STL) | 0.5 -190 | 0.5 +145 |
Cleveland Guardians vs St. Louis Cardinals RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Alec Burleson (STL) | 0.5 +125 | 0.5 -160 |
| Lars Nootbaar (STL) | 0.5 +145 | 0.5 -190 |
| Willson Contreras (STL) | 0.5 +155 | 0.5 -210 |
| Brendan Donovan (STL) | 0.5 +170 | 0.5 -225 |
| Nolan Arenado (STL) | 0.5 +180 | 0.5 -250 |
Cleveland Guardians vs St. Louis Cardinals Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Sonny Gray (STL) | 5.5 -140 | 5.5 +105 |
St. Louis Cardinals Starting Pitcher Stats & Trends
starting pitcher – away
Cleveland Guardians Starting Pitcher Stats & Trends
starting pitcher – home
St. Louis Cardinals Keys to the Game vs. the Cleveland Guardians
keys to the game – away
Cleveland Guardians Keys to the Game vs. the St. Louis Cardinals
keys to the game – home
St. Louis Cardinals Hitting Stats & Trends
team hitters – away
Cleveland Guardians Hitting Stats & Trends
team hitters – home
St. Louis Cardinals Pitching Stats & Trends
team pitchers – away
Cleveland Guardians Pitching Stats & Trends
team pitchers – home
More MLB Reading:
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