• The Orioles are -145 favorites vs the Tigers
• Tigers vs Orioles Over / Under today: 8.5 Runs
• Tigers / Orioles TV Channel: ATV

The Detroit Tigers (+118) visit Oriole Park at Camden Yards to take on the Baltimore Orioles (-145) on May 22, 2026. First pitch is scheduled for 7:15 pm in Baltimore, MD.

This season, the Tigers are 20-31 against the spread (ATS), while the Orioles are 21-29 ATS.

Tigers vs Orioles Starting Pitchers Today:

• Tigers starting pitcher: Jack Flaherty 0-5, 5.78 ERA
• Orioles starting pitcher: Chris Bassitt 3-3, 5.45 ERA

Tigers vs. Orioles Odds, Run Line, Over/Under & Moneyline

Tigers vs Orioles Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Friday‘s MLB game with 54.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Tigers vs Orioles and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Tigers players for Friday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Bets Today:

• Zach McKinstry has hit the Runs Under in 23 of his last 25 games (+18.60 Units / 32% ROI)
• Matt Vierling has hit the Home Runs Over in 2 of his last 6 games (+12.50 Units / 208% ROI)
• Colt Keith has hit the Hits Runs and RBIs Under in 16 of his last 20 games (+11.60 Units / 45% ROI)
• Kevin McGonigle has hit the Singles Over in 16 of his last 20 away games (+11.30 Units / 48% ROI)
• Riley Greene has hit the Hits Over in 20 of his last 25 games (+10.20 Units / 21% ROI)

And here are some favorite MLB player prop bets for Orioles players for Friday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Best Bets Today:

• Samuel Basallo has hit the Home Runs Over in 4 of his last 10 games at home (+17.90 Units / 179% ROI)
• Taylor Ward has hit the Walks Over in 20 of his last 25 games (+15.25 Units / 55% ROI)
• Gunnar Henderson has hit the Runs Under in 17 of his last 20 games (+13.35 Units / 51% ROI)
• Taylor Ward has hit the Total Bases Under in 16 of his last 20 games (+11.95 Units / 38% ROI)
• Jackson Holliday has hit the Hits Runs and RBIs Under in his last 10 games (+10.00 Units / 79% ROI)

Tigers Best Bets Today:

• The Detroit Tigers have hit the Team Total Under in 13 of their last 15 games (+10.80 Units / 61% ROI)
• The Detroit Tigers have hit the Game Total Under in 15 of their last 22 games (+7.30 Units / 30% ROI)
• The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Under in 6 of their last 7 games (+5.10 Units / 63% ROI)
• The Detroit Tigers have covered the 1st Five Innings (F5) Run Line in 9 of their last 16 away games (+0.80 Units / 4% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have hit the Game Total Under in 32 of their last 50 games at home (+13.30 Units / 24% ROI)
• The Baltimore Orioles have hit the Team Total Under in 31 of their last 50 games at home (+9.20 Units / 16% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 25 of their last 40 games at home (+7.95 Units / 16% ROI)
• The Baltimore Orioles have covered the Run Line in 9 of their last 17 games at home (+3.50 Units / 18% ROI)
• The Baltimore Orioles have hit the Moneyline in 3 of their last 5 games at home (+1.50 Units / 28% ROI)

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 21-27 against the Run Line (-8.25 Units / -12.59% ROI).

• 20-31 when betting on the Moneyline for -15.4 Units / -24.76% ROI
• 22-27 when betting on the total runs Over for -7.55 Units / -13.46% ROI
• 27-22 when betting on the total runs Under for +2.95 Units / 5.26% ROI

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 21-29 against the Run Line (-10.05 Units / -15.89% ROI).

• 21-29 when betting on the Moneyline for -11.4 Units / -19.31% ROI
• 28-21 when betting on the total runs Over for +4.7 Units / 8.51% ROI
• 21-28 when betting on the total runs Under for -9.75 Units / -17.79% ROI

Orioles vs Tigers Home Run Prop Bets Today

Orioles vs Tigers Total Hits Prop Bets Today

Orioles vs Tigers Strikeout Prop Bets Today

Tigers Keys to the Game vs. the Orioles

The Tigers are just 13-4 (.765) when leading entering the 8th inning this season — lowest in MLB; League Avg: .894.

The Tigers are just 1-9 (.100) when their opponents score in the first inning this season — lowest in MLB; League Avg: .364.

The Tigers are just 14-7 (.667) when leading entering the 7th inning this season — lowest in MLB; League Avg: .863.

The Tigers are just 7-19 (.269) on the road this season — lowest in MLB; League Avg: .472.

Orioles Keys to the Game vs. the Tigers

The Orioles are 7-2 (.778) when they’ve scored in the first inning this season — 5th best in MLB; League Avg: .636.

The Orioles are just 5-24 (.172) when scoring 4 or fewer runs this season — 2nd lowest in MLB; League Avg: .279.

The Orioles are just 2-102 (.019) when trailing entering the 9th inning since the 2025 season — 3rd lowest in MLB; League Avg: .046.

The Orioles are just 6-10 (.375) when tied entering the 8th inning since the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

Tigers Hitting Stats & Trends

Tigers hitters have drawn walks in 14% of their PA’s against LHP this season — best in MLB.

The Tigers are batting just .212 against LHP this season — 2nd lowest in MLB.

Tigers hitters have chased 12% of pitches out of the zone on the first pitch of at-bats this season — lowest in MLB.

Tigers hitters have chased 25% of pitches out of the zone against LHP this season — lowest in MLB.

Orioles Hitting Stats & Trends

Orioles hitters are slugging just .150 on pitches out of the zone this season — lowest in MLB.

Orioles hitters are slugging just .398 on the first pitch of at-bats this season — lowest in MLB.

The Orioles are batting just .259 on the first pitch of at-bats this season — lowest in MLB.

The Orioles are batting just .147 with two-strikes this season — 2nd lowest in MLB.

Tigers Pitching Stats & Trends

Tigers pitchers have 57 three-pitch strikeouts this season — 4th fewest in MLB.

Tigers pitchers have 57 three-pitch strikeouts this season — 4th fewest in MLB.

Tigers pitchers have a first-pitch strike rate of 63% this season — 4th highest in MLB.

Tigers pitchers have induced opposing hitters to ground into 40 double plays in 368 opportunities (11%) this season — tied for 4th best in MLB.

Orioles Pitching Stats & Trends

Orioles pitchers have an ERA of 7.45 (110.0 IP) against division opponents this season — highest in MLB.

Orioles pitchers have an ERA of 4.97 (438.2 IP) this season — 4th highest in MLB.

Orioles pitchers have a strikeout rate of 27% in close and late situations this season — 4th best in MLB.

Orioles pitchers have an ERA of 5.86 (221.1 IP) on the road this season — highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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