Tigers vs Pirates Prediction, Odds & Player Prop Bets Today – MLB, Jul 22

Pirates player Andrew McCutchen smiling while running.
(AP Photo/Charles Rex Arbogast)
  • The Tigers are -130 favorites vs the Pirates
  • Tigers vs Pirates Over / Under today: 8 Runs
  • Tigers / Pirates TV Channel: FDDT | SNPT

The Detroit Tigers (-130) visit PNC Park to take on the Pittsburgh Pirates (+110) on Tuesday, July 22, 2025. First pitch is scheduled for 6:40pm EDT in Pittsburgh, PA.

This season, the Tigers are 60-41 against the spread (ATS), while the Pirates are 50-49 ATS.

Tigers vs Pirates Starting Pitchers Today:

  • Tigers starting pitcher: Casey Mize 9-3, 3.15 ERA
  • Pirates starting pitcher: Mitch Keller 3-10, 3.48 ERA

Tigers vs. Pirates Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Tigers-1.5 +125O 8 -115-130
Pirates +1.5 -155U 8 -105+110

Tigers vs Pirates Prediction for Today’s Game

Based on recent trends the model predicts the Tigers will win Tuesday‘s MLB game with 56.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Tigers players for Tuesday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Bets Today:

  • Matt Vierling has hit the Runs Under in 17 of his last 20 games (+11.70 Units / 31% ROI)
  • Riley Greene has hit the Home Runs Over in 3 of his last 6 games (+10.40 Units / 173% ROI)
  • Colt Keith has hit the Hits Under in his last 5 games (+6.85 Units / 84% ROI)
  • Matt Vierling has hit the Hits Runs and RBIs Under in 14 of his last 20 games (+6.80 Units / 26% ROI)
  • Riley Greene has hit the Singles Under in 8 of his last 9 away games (+6.65 Units / 58% ROI)

And here are some favorite MLB player prop bets for Pirates players for Tuesday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Best Bets Today:

  • Ke’Bryan Hayes has hit the Runs Over in 11 of his last 15 games at home (+13.90 Units / 93% ROI)
  • Ke’Bryan Hayes has hit the Hits Over in 14 of his last 15 games at home (+12.10 Units / 43% ROI)
  • Ke’Bryan Hayes has hit the Total Bases Over in 13 of his last 15 games at home (+10.05 Units / 37% ROI)
  • Ke’Bryan Hayes has hit the Hits Runs and RBIs Over in 12 of his last 15 games at home (+9.45 Units / 60% ROI)
  • Ke’Bryan Hayes has hit the Singles Over in 12 of his last 15 games at home (+8.40 Units / 47% ROI)
  • The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Over in 59 of their last 101 games (+16.05 Units / 14% ROI)
  • The Detroit Tigers have hit the Moneyline in 60 of their last 98 games (+11.20 Units / 8% ROI)
  • The Detroit Tigers have hit the 1st Five Innings (F5) Moneyline in 53 of their last 100 games (+10.35 Units / 7% ROI)
  • The Detroit Tigers have hit the Team Total Over in 58 of their last 101 games (+8.85 Units / 7% ROI)
  • The Detroit Tigers have hit the Game Total Over in 23 of their last 39 away games (+6.45 Units / 15% ROI)
  • The Pittsburgh Pirates have hit the Team Total Under in 64 of their last 100 games (+24.75 Units / 21% ROI)
  • The Pittsburgh Pirates have hit the Game Total Under in 53 of their last 89 games (+16.95 Units / 17% ROI)
  • The Pittsburgh Pirates have covered the Run Line in 38 of their last 63 games (+12.75 Units / 15% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Under in 41 of their last 68 games (+10.10 Units / 12% ROI)
  • The Pittsburgh Pirates have hit the Moneyline in 20 of their last 32 games at home (+8.00 Units / 22% ROI)

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 51-50 against the Run Line (-5.05 Units / -3.91% ROI).

  • 60-41 when betting on the Moneyline for +8.2 Units / 5.43% ROI
  • 50-47 when betting on the total runs Over for -1 Units / -0.91% ROI
  • 47-50 when betting on the total runs Under for -8 Units / -7.13% ROI

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 50-49 against the Run Line (-6.75 Units / -5.11% ROI).

  • 40-61 when betting on the Moneyline for -17.5 Units / -15.6% ROI
  • 40-58 when betting on the total runs Over for -23.75 Units / -21.31% ROI
  • 58-40 when betting on the total runs Under for +14.4 Units / 13% ROI

Pirates vs Tigers Home Run Prop Bets Today

Over Under
Oneil Cruz (PIT) 0.5 +375 0.5 -525
Riley Greene (DET) 0.5 +500 0.5 -750
Spencer Torkelson (DET) 0.5 +500 0.5 -700
Bryan Reynolds (PIT) 0.5 +625 0.5 -1000
Andrew McCutchen (PIT) 0.5 +675 0.5 -1100

Pirates vs Tigers Total Hits Prop Bets Today

Over Under
Spencer Horwitz (PIT) 0.5 -235 0.5 +175
Wenceel Perez (DET) 0.5 -235 0.5 +180
Andrew McCutchen (PIT) 0.5 -225 0.5 +170
Zach McKinstry (DET) 0.5 -225 0.5 +170
Bryan Reynolds (PIT) 0.5 -220 0.5 +165

Pirates vs Tigers RBI Prop Bets Today

Over Under
Riley Greene (DET) 0.5 +120 0.5 -160
Spencer Torkelson (DET) 0.5 +150 0.5 -200
Nick Gonzales (PIT) 0.5 +160 0.5 -210
Oneil Cruz (PIT) 0.5 +160 0.5 -210
Wenceel Perez (DET) 0.5 +175 0.5 -235

Pirates vs Tigers Strikeout Prop Bets Today

Over Under
Mitch Keller (PIT) 4.5 -150 4.5 +115
Casey Mize (DET) 4.5 -105 4.5 -125

Right-handed hitters have a line drive rate of just 18% (23/131) against Casey Mize this season — tied for 5th lowest in MLB among starting pitchers with at least 39 total IP; League Avg: 24% — 96th Percentile.

Hitters have chased just 30 of Casey Mize’s 131 breaking balls down out of the zone (chase rate of 23%) this season — 3rd lowest in MLB among starting pitchers with at least 39 total IP; League Avg: 34% — second Percentile.

Casey Mize has a first-pitch in-zone of 61% (227/371) this season — 13th best in MLB among starting pitchers with at least 39 total IP; League Avg: 56% — 89th Percentile.

Casey Mize has a first-pitch strike rate of 69% (255/371) this season — 6th highest in MLB among starting pitchers with at least 39 total IP; League Avg: 63% — 95th Percentile.

Pirates Starting Pitcher Stats & Trends

Opponents have a miss rate of just 19% (174/914) against Mitch Keller this season — 5th lowest among qualified SPs in MLB; League Avg: 25% — seventh Percentile.

Mitch Keller has a strike rate of 70% (272/387) with runners in scoring position this season — highest among qualified SPs in MLB; League Avg: 64% — 100th Percentile.

Opponents are hitting just .246 (14-for-57) against Mitch Keller on the first pitch of at-bats this season — 4th best among qualified SPs in MLB; League Avg: .335 — 95th Percentile.

Mitch Keller has a strikeout rate of just 18% (33 SO in 180 PAs) when going through the lineup the first time in a game this season — tied for 9th lowest among qualified SPs in MLB; League Avg: 25% — 15th Percentile.

Tigers Keys to the Game vs. the Pirates

The Tigers are 33-3 (.917) when they’ve had 10 or more hits this season — 2nd best in MLB; League Avg: .747.

The Tigers were 13-55 (.191) when trailing entering the 8th inning in the 2024 season — best in MLB; League Avg: .100.

The Tigers are 72-7 (.911) when they’ve had 10 or more hits since last season — best in MLB; League Avg: .749.

The Tigers were 18-54 (.250) when trailing entering the 7th inning in the 2024 season — best in MLB; League Avg: .143.

Pirates Keys to the Game vs. the Tigers

The Pirates are just 1-23 (.042) when allowing 2 or more home runs this season — 2nd lowest in MLB; League Avg: .284.

The Pirates are just 8-60 (.118) when allowing 2 or more home runs since last season — lowest in MLB; League Avg: .287.

The Pirates are just 10-73 (.120) when allowing 10 or more hits since last season — 2nd lowest in MLB; League Avg: .251.

The Pirates are just 1-52 (.019) when trailing entering the 8th inning this season — lowest in MLB; League Avg: .092.

Tigers hitters have an OPS of just .602 (328 PA’s) over the last 14 days — lowest in MLB; League Avg: .734.

The Tigers are batting .263 against LHP this season — 3rd best in MLB; League Avg: .241.

Tigers hitters have drawn walks in 10% of their PA’s against LHP this season — 3rd best in MLB; League Avg: 8%.

Tigers hitters have an OPS of just .469 (139 PA’s) over the past seven days (4 games) — lowest in MLB; League Avg: .747.

The Pirates are batting just .130 in lefty-lefty matchups this season — lowest in MLB; League Avg: .228.

Pirates hitters have an OBP of just .275 (1,834 PA’s) on the road this season — 2nd lowest in MLB; League Avg: .310.

Pirates hitters have an OPS of just .523 (519 PA’s) this month (15 games) — lowest in MLB; League Avg: .729.

Pirates hitters are slugging just .342 against RHP this season — 2nd lowest in MLB; League Avg: .406.

Tigers pitchers have a strikeout rate of 35% over the past seven days (4 games) — best in MLB; League Avg: 21%.

Tigers pitchers have walked 5% of batters when facing the leadoff batter in the inning over the last 14 days — 3rd best in MLB; League Avg: 8%.

Tigers pitchers have walked 7% of batters since last season — 3rd best in MLB; League Avg: 8%.

Tigers pitchers have a strikeout rate of 25% over the last 14 days — 3rd best in MLB; League Avg: 22%.

Pirates pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — best in MLB; League Avg: 8%.

Pirates pitchers have won only 0% of games in which they have allowed their opponent to score in three different innings on the road this season — lowest in MLB; League Avg: 26%.

The Pirates have won just 4% of road games in which their opponents scored first this season — lowest in MLB; League Avg: 25%.

Pirates pitchers have won only 10% of games in which they have allowed their opponent to score in three different innings this season — 3rd lowest in MLB; League Avg: 27%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.