• The Astros are -140 favorites vs the Twins
• Twins vs Astros Over / Under today: 9 Runs
• Twins / Astros TV Channel: TWTV | SCHN

The Minnesota Twins (+115) visit Daikin Park to take on the Houston Astros (-140) on June 29, 2026. First pitch is scheduled for 8:10 pm in Houston, TX.

This season, the Twins are 40-45 against the spread (ATS), while the Astros are 42-44 ATS.

Twins vs Astros Starting Pitchers Today:

• Twins starting pitcher: Zebby Matthews 3-5, 4.63 ERA
• Astros starting pitcher: Peter Lambert 6-4, 3.30 ERA

Twins vs. Astros Odds, Run Line, Over/Under & Moneyline

Twins vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Monday‘s MLB game with 57.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Twins vs Astros and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Twins players for Monday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

• Victor Caratini has hit the Home Runs Over in 3 of his last 9 games (+20.00 Units / 222% ROI)
• Josh Bell has hit the Hits Over in 22 of his last 25 games (+16.45 Units / 33% ROI)
• Josh Bell has hit the Total Bases Over in 18 of his last 25 games (+15.80 Units / 56% ROI)
• Josh Bell has hit the Hits Runs and RBIs Over in 20 of his last 25 games (+14.60 Units / 52% ROI)
• Trevor Larnach has hit the Walks Under in 18 of his last 20 away games (+13.80 Units / 33% ROI)

And here are some favorite MLB player prop bets for Astros players for Monday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

• Jose Altuve has hit the Home Runs Over in 4 of his last 9 games at home (+18.10 Units / 201% ROI)
• Joey Loperfido has hit the Singles Under in 14 of his last 15 games (+12.65 Units / 55% ROI)
• Isaac Paredes has hit the Total Bases Over in 18 of his last 25 games at home (+10.60 Units / 30% ROI)
• Cam Smith has hit the Hits Under in 16 of his last 25 games at home (+9.50 Units / 38% ROI)
• Yordan Alvarez has hit the RBIs Under in 16 of his last 20 games (+9.45 Units / 28% ROI)

Twins Best Bets Today:

• The Minnesota Twins have hit the Game Total Over in 25 of their last 35 away games (+15.20 Units / 40% ROI)
• The Minnesota Twins have hit the Team Total Over in 31 of their last 50 games (+10.50 Units / 18% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Over in 14 of their last 20 away games (+8.10 Units / 34% ROI)
• The Minnesota Twins have covered the Run Line in 27 of their last 45 games (+6.10 Units / 10% ROI)
• The Minnesota Twins have hit the Moneyline in 12 of their last 21 away games (+5.00 Units / 23% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the Game Total Over in 30 of their last 50 games at home (+9.80 Units / 18% ROI)
• The Houston Astros have hit the Moneyline in 22 of their last 35 games (+9.70 Units / 25% ROI)
• The Houston Astros have covered the Run Line in 22 of their last 35 games (+7.65 Units / 15% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 14 of their last 20 games (+6.80 Units / 26% ROI)
• The Houston Astros have hit the Team Total Over in 20 of their last 35 games (+5.00 Units / 13% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 46-39 against the Run Line (-4.35 Units / -3.58% ROI).

• 40-45 when betting on the Moneyline for -3.45 Units / -3.72% ROI
• 50-30 when betting on the total runs Over for +16.9 Units / 18.02% ROI
• 30-50 when betting on the total runs Under for -24.95 Units / -26.76% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 42-44 against the Run Line (-8.55 Units / -7.27% ROI).

• 42-44 when betting on the Moneyline for -3.3 Units / -3.35% ROI
• 45-37 when betting on the total runs Over for +3.3 Units / 3.43% ROI
• 37-45 when betting on the total runs Under for -12.1 Units / -13% ROI

Astros vs Twins Home Run Prop Bets Today

Astros vs Twins Total Hits Prop Bets Today

Astros vs Twins Strikeout Prop Bets Today

Twins Keys to the Game vs. the Astros

The Twins are just 0-38 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .057.

The Twins are just 0-35 (.000) when trailing entering the 8th inning this season — lowest in MLB; League Avg: .104.

The Twins are just 3-8 (.273) when tied entering the 7th inning this season — 4th lowest in MLB; League Avg: .500.

The Twins are just 8-27 (.229) when tied entering the 7th inning since the 2025 season — lowest in MLB; League Avg: .500.

Astros Keys to the Game vs. the Twins

The Astros are just 13-18 (.419) vs the bottom 10 runs allowed teams this season Today, they face the Twins (27th runs allowed).

The Astros are 7-1 (.875) when tied entering the 8th inning this season — best in MLB; League Avg: .500.

The Astros are 31-2 (.939) when leading entering the 7th inning this season — 4th best in MLB; League Avg: .858.

The Astros are 37-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB; League Avg: .943.

Twins Hitting Stats & Trends

The Twins are batting just .276 on the first pitch of at-bats this season — lowest in MLB.

Twins hitters have 50 extra-base hits out of 102 total hits (49%) on the first pitch of at-bats this season — best in MLB.

The Twins are batting .290 with runners in scoring position this season — best in MLB.

Twins hitters have a 52% QAB rate with runners in scoring position this season — best in MLB.

Astros Hitting Stats & Trends

Astros hitters have drawn walks in 7% of their PA’s against LHP this season — 3rd lowest in MLB.

Astros hitters have struck out in just 20% of their PA’s against LHP this season — 4th best in MLB.

Astros hitters have 256 extra-base hits out of 701 total hits (36%) this season — tied for 4th best in MLB.

Astros hitters have 57 extra-base hits out of 122 total hits (47%) on the first pitch of at-bats this season — 2nd best in MLB.

Twins Pitching Stats & Trends

Opponents have a groundball rate of just 39% against Twins pitchers this season — 2nd lowest in MLB.

Twins pitchers have an ERA of 5.49 (342.1 IP) on the road this season — highest in MLB.

Twins pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 3rd highest in MLB.

Twins pitchers have an ERA of 4.86 (750.2 IP) this season — 3rd highest in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 11% of batters this season — 3rd highest in MLB.

Astros pitchers have walked 11% of batters when facing the leadoff batter in the inning this season — tied for highest in MLB.

Opponents have a groundball rate of just 40% against Astros pitchers this season — 3rd lowest in MLB.

Astros pitchers have a first-pitch strike rate of just 58% this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

Bet now on Twins vs Astros and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.