• The Twins are -120 favorites vs the Guardians
• Twins vs Guardians Over / Under today: 7.5 Runs
• Twins / Guardians TV Channel: GDTV | TWTV

The Minnesota Twins (-120) visit Progressive Field to take on the Cleveland Guardians (+100) on July 20, 2026. First pitch is scheduled for 6:40 pm in Cleveland, OH.

This season, the Twins are 49-51 against the spread (ATS), while the Guardians are 48-51 ATS.

Twins vs Guardians Starting Pitchers Today:

• Twins starting pitcher: Joe Ryan 6-5, 2.85 ERA
• Guardians starting pitcher: Tanner Bibee 3-9, 3.94 ERA

Twins vs. Guardians Odds, Run Line, Over/Under & Moneyline

Twins vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Monday‘s MLB game with 53.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Twins vs Guardians and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Twins players for Monday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

• Josh Bell has hit the Hits Over in 18 of his last 20 away games (+14.95 Units / 40% ROI)
• Josh Bell has hit the Total Bases Over in 15 of his last 20 away games (+14.50 Units / 64% ROI)
• Luke Keaschall has hit the Home Runs Over in 2 of his last 7 away games (+13.00 Units / 186% ROI)
• Tristan Gray has hit the Hits Runs and RBIs Under in 15 of his last 20 games (+10.35 Units / 41% ROI)
• Tristan Gray has hit the Runs Under in 17 of his last 20 away games (+10.30 Units / 22% ROI)

And here are some favorite MLB player prop bets for Guardians players for Monday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

• Chase DeLauter has hit the Home Runs Over in 4 of his last 10 games (+14.60 Units / 146% ROI)
• Chase DeLauter has hit the Hits Over in 18 of his last 20 games at home (+13.65 Units / 31% ROI)
• Chase DeLauter has hit the Singles Over in 16 of his last 20 games at home (+11.55 Units / 49% ROI)
• Chase DeLauter has hit the Walks Under in 17 of his last 20 games at home (+10.95 Units / 27% ROI)
• Brayan Rocchio has hit the Hits Runs and RBIs Over in 15 of his last 20 games (+10.30 Units / 47% ROI)

Twins Best Bets Today:

• The Minnesota Twins have hit the Game Total Over in 30 of their last 45 away games (+15.60 Units / 32% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 30 away games (+9.45 Units / 26% ROI)
• The Minnesota Twins have hit the Team Total Over in 28 of their last 45 away games (+8.85 Units / 16% ROI)
• The Minnesota Twins have hit the Moneyline in 17 of their last 30 away games (+7.15 Units / 23% ROI)
• The Minnesota Twins have covered the Run Line in 19 of their last 30 away games (+4.60 Units / 10% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 15 of their last 23 games (+7.45 Units / 28% ROI)
• The Cleveland Guardians have hit the Game Total Under in 29 of their last 50 games (+5.45 Units / 10% ROI)
• The Cleveland Guardians have hit the Team Total Under in 29 of their last 50 games (+5.40 Units / 9% ROI)
• The Cleveland Guardians have covered the Run Line in 6 of their last 8 games (+4.00 Units / 35% ROI)
• The Cleveland Guardians have hit the Moneyline in 5 of their last 7 games (+3.00 Units / 38% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 54-46 against the Run Line (-4.3 Units / -3.03% ROI).

• 49-51 when betting on the Moneyline for +0.15 Units / 0.14% ROI
• 55-39 when betting on the total runs Over for +11.7 Units / 10.6% ROI
• 39-55 when betting on the total runs Under for -21.55 Units / -19.65% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 48-51 against the Run Line (-5.9 Units / -4.55% ROI).

• 52-48 when betting on the Moneyline for +2.3 Units / 1.95% ROI
• 47-53 when betting on the total runs Over for -10.85 Units / -9.93% ROI
• 53-47 when betting on the total runs Under for +0.75 Units / 0.68% ROI

Guardians vs Twins Home Run Prop Bets Today

Guardians vs Twins Total Hits Prop Bets Today

Guardians vs Twins Strikeout Prop Bets Today

Twins Keys to the Game vs. the Guardians

The Twins are just 12-19 (.387) vs the bottom 10 runs allowed teams this season Today, they face the Guardians (eighth runs allowed).

The Twins are just 0-41 (.000) when trailing entering the 8th inning this season — lowest in MLB; League Avg: .098.

The Twins are just 0-44 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .053.

The Twins are just 4-38 (.095) when trailing entering the 7th inning this season — 5th lowest in MLB; League Avg: .136.

Guardians Keys to the Game vs. the Twins

The Guardians are 21-16 (.568) vs the top 10 runs allowed teams this season Today, they face Twins (24th in runs allowed).

The Guardians are 17-4 (.810) when they’ve hit 2 or more home runs this season — 4th best in MLB; League Avg: .698.

The Guardians are 10-1 (.909) when they’ve had 5 or more XBH this season — tied for 4th best in MLB; League Avg: .786.

The Guardians are 37-3 (.925) when leading entering the 7th inning this season — 4th best in MLB; League Avg: .864.

Twins Hitting Stats & Trends

The Twins are batting just .290 on the first pitch of at-bats this season — lowest in MLB.

Twins hitters have 59 extra-base hits out of 123 total hits (48%) on the first pitch of at-bats this season — best in MLB.

Twins hitters are slugging just .359 against LHP this season — 4th lowest in MLB.

Twins hitters have an OPS of .781 (1,113 PA’s) in righty-righty matchups this season — 2nd best in MLB.

Guardians Hitting Stats & Trends

Guardians hitters are slugging just .348 against LHP this season — 2nd lowest in MLB.

Guardians hitters have an OBP of just .264 (423 PA’s) when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.

The Guardians are batting just .194 when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.

Guardians hitters have an OPS of just .659 (1,162 PA’s) against LHP this season — 3rd lowest in MLB.

Twins Pitching Stats & Trends

Opponents have a groundball rate of just 39% against Twins pitchers this season — 3rd lowest in MLB.

Twins pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 3rd highest in MLB.

Opponents have a groundball batting average of .294 against Twins pitchers with runners on base this season — highest in MLB.

Twins pitchers have an ERA of 5.15 (419.2 IP) on the road this season — 2nd highest in MLB.

Guardians Pitching Stats & Trends

Opponents have a miss rate of 27% against Guardians pitchers this season — 4th best in MLB.

Guardians pitchers have a strikeout rate of 24% this season — 4th best in MLB.

Guardians pitchers have a strikeout rate of 29% in close and late situations this season — best in MLB.

Guardians pitchers have allowed innings of 3+ runs in 4% of innings played this season — lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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