• The Mets are -160 favorites vs the Twins
• Twins vs Mets Over / Under today: 8 Runs
• Twins / Mets TV Channel: TWTV | SNY

The Minnesota Twins (+135) visit Citi Field to take on the New York Mets (-160) on April 22, 2026. First pitch is scheduled for 7:10 pm in Flushing, Queens, NY.

This season, the Twins are 12-11 against the spread (ATS), while the Mets are 8-15 ATS.

Twins vs Mets Starting Pitchers Today:

• Twins starting pitcher: Connor Prielipp 0-0, 0.00 ERA
• Mets starting pitcher: Clay Holmes 2-2, 1.96 ERA

Twins vs. Mets Odds, Run Line, Over/Under & Moneyline

Twins vs Mets Prediction for Today’s Game

Based on recent trends the model predicts the Mets will win Wednesday‘s MLB game with 55.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Twins vs Mets and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Twins players for Wednesday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

• Brooks Lee has hit the Home Runs Over in 3 of his last 10 games (+18.50 Units / 185% ROI)
• Royce Lewis has hit the Singles Under in 19 of his last 25 away games (+10.25 Units / 27% ROI)
• Matt Wallner has hit the Runs Over in 14 of his last 25 games (+8.05 Units / 32% ROI)
• Trevor Larnach has hit the Walks Over in 7 of his last 10 games (+7.35 Units / 74% ROI)
• Josh Bell has hit the Hits Runs and RBIs Over in 13 of his last 20 games (+6.35 Units / 30% ROI)

And here are some favorite MLB player prop bets for Mets players for Wednesday‘s game, looking at profitable historical betting trends:

Best Mets Player Prop Best Bets Today:

• Marcus Semien has hit the Total Bases Under in 20 of his last 25 games at home (+15.50 Units / 43% ROI)
• Francisco Lindor has hit the Hits Over in 20 of his last 25 games at home (+14.15 Units / 30% ROI)
• Marcus Semien has hit the Hits Runs and RBIs Under in 17 of his last 20 games at home (+12.85 Units / 48% ROI)
• Francisco Lindor has hit the Walks Under in 14 of his last 15 games (+12.40 Units / 45% ROI)
• Marcus Semien has hit the Runs Under in 20 of his last 25 games (+11.25 Units / 22% ROI)

Twins Best Bets Today:

• The Minnesota Twins have hit the Team Total Over in 17 of their last 22 games (+11.40 Units / 43% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Moneyline in 16 of their last 30 games (+8.25 Units / 25% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Under in 30 of their last 50 away games (+7.95 Units / 14% ROI)
• The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 19 of their last 30 games (+6.75 Units / 19% ROI)
• The Minnesota Twins have hit the Game Total Over in 8 of their last 10 games (+5.80 Units / 53% ROI)

Mets Best Bets Today:

• The New York Mets have hit the Team Total Under in 16 of their last 21 games (+11.05 Units / 47% ROI)
• The New York Mets have hit the 1st Five Innings (F5) Team Total Under in 17 of their last 25 games (+8.25 Units / 26% ROI)
• The New York Mets have hit the Game Total Over in 28 of their last 50 games at home (+5.75 Units / 11% ROI)
• The New York Mets have hit the 1st Five Innings (F5) Moneyline in 2 of their last 5 games (+0.10 Units / 2% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 13-10 against the Run Line (+0.45 Units / 1.39% ROI).

• 12-11 when betting on the Moneyline for +2.45 Units / 9.94% ROI
• 13-9 when betting on the total runs Over for +3.05 Units / 12.1% ROI
• 9-13 when betting on the total runs Under for -5.45 Units / -21.46% ROI

Mets Against the Spread (ATS) Record

Against the spread this season, the Mets are 8-15 against the Run Line (-6.55 Units / -25.24% ROI).

• 7-16 when betting on the Moneyline for -14.7 Units / -47.57% ROI
• 10-11 when betting on the total runs Over for -2.15 Units / -8.46% ROI
• 11-10 when betting on the total runs Under for -0.05 Units / -0.2% ROI

Mets vs Twins Home Run Prop Bets Today

Mets vs Twins Total Hits Prop Bets Today

Mets vs Twins Strikeout Prop Bets Today

Twins Keys to the Game vs. the Mets

The Twins are just 6-21 (.222) when tied entering the 7th inning since the 2025 season — lowest in MLB; League Avg: .500.

The Twins were just 5-19 (.208) when tied entering the 7th inning in the 2025 season — lowest in MLB; League Avg: .500.

The Twins were just 7-14 (.333) when tied entering the 8th inning in the 2025 season — 3rd lowest in MLB; League Avg: .500.

The Twins are just 0-8 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .105.

Mets Keys to the Game vs. the Twins

The Mets are just 4-3 (.571) when leading entering the 7th inning this season — lowest in MLB; League Avg: .866.

The Mets were 8-2 (.800) when tied entering the 8th inning in the 2025 season — best in MLB; League Avg: .500.

The Mets were just 0-70 (.000) when trailing entering the 9th inning in the 2025 season — lowest in MLB; League Avg: .043.

The Mets are just 6-14 (.300) when allowing 5 or more extra base hits this season — lowest in MLB; League Avg: .525.

Twins Hitting Stats & Trends

Twins hitters are slugging just .163 on pitches out of the zone since the 2025 season — 2nd lowest in MLB.

The Twins are batting just .124 on pitches out of the zone since the 2025 season — 2nd lowest in MLB.

Twins hitters slugged just .163 on pitches out of the zone in the 2025 season — 2nd lowest in MLB.

The Twins batted just .226 when facing the starting pitcher for the 3rd time in a game in the 2025 season — lowest in MLB.

Mets Hitting Stats & Trends

Mets hitters have an OPS of just .617 (644 PA’s) against RHP this season — lowest in MLB.

Mets hitters had a Hard-Hit Rate of 48% against RHP in the 2025 season — best in MLB.

Mets hitters are slugging just .328 against RHP this season — lowest in MLB.

Mets hitters have an OBP of just .270 (660 PA’s) this month (18 games) — lowest in MLB.

Twins Pitching Stats & Trends

Opponents have a groundball rate of just 38% against Twins pitchers this season — lowest in MLB.

Opponents had a groundball rate of just 39% against Twins pitchers in the 2025 season — 2nd lowest in MLB.

Twins pitchers induced opposing hitters to ground into just 80 double plays in 1,117 opportunities (7%) in the 2025 season — lowest in MLB.

Twins pitchers have walked 8% of batters since the 2025 season — 4th best in MLB.

Mets Pitching Stats & Trends

Opponents had a groundball rate of 47% against Mets pitchers in the 2025 season — highest in MLB.

Opponents have a groundball rate of 47% against Mets pitchers since the 2025 season — highest in MLB.

The longest HR allowed by the Mets pitchers in the 2025 season traveled 439.9 feet — — shortest in MLB

Opponents have a groundball batting average of just .215 against Mets pitchers this season — 5th best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

Bet now on Twins vs Mets and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.