• The Twins are -110 favorites vs the Nationals
• Twins vs Nationals Over / Under today: 9 Runs
• Twins / Nationals TV Channel: TWTV | NATV

The Minnesota Twins (-110) visit Nationals Park to take on the Washington Nationals (-110) on May 5, 2026. First pitch is scheduled for 6:45 pm in Washington, DC.

This season, the Twins are 15-20 against the spread (ATS), while the Nationals are 20-14 ATS.

Twins vs Nationals Starting Pitchers Today:

• Twins starting pitcher: Taj Bradley 3-1, 2.86 ERA
• Nationals starting pitcher: Cade Cavalli 1-1, 3.90 ERA

Twins vs. Nationals Odds, Run Line, Over/Under & Moneyline

Twins vs Nationals Prediction for Today’s Game

Based on recent trends the model predicts the Nationals will win Tuesday‘s MLB game with 52.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Twins vs Nationals and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Twins players for Tuesday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

• Brooks Lee has hit the Home Runs Over in 4 of his last 9 away games (+29.00 Units / 322% ROI)
• Trevor Larnach has hit the Hits Runs and RBIs Over in 14 of his last 20 games (+9.55 Units / 43% ROI)
• Josh Bell has hit the Total Bases Under in 14 of his last 20 games (+8.75 Units / 30% ROI)
• Byron Buxton has hit the Hits Over in 13 of his last 15 games (+8.40 Units / 26% ROI)
• Matt Wallner has hit the Runs Under in his last 8 games (+8.00 Units / 48% ROI)

And here are some favorite MLB player prop bets for Nationals players for Tuesday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Best Bets Today:

• Daylen Lile has hit the Home Runs Over in 3 of his last 9 games at home (+22.50 Units / 250% ROI)
• Luis Garcia has hit the Hits Under in 15 of his last 20 games (+16.80 Units / 69% ROI)
• Luis Garcia has hit the Total Bases Under in 17 of his last 20 games (+11.27 Units / 31% ROI)
• Jorbit Vivas has hit the Singles Over in 13 of his last 20 games (+9.45 Units / 47% ROI)
• Jacob Young has hit the Hits Runs and RBIs Over in 13 of his last 20 games at home (+7.60 Units / 33% ROI)

Twins Best Bets Today:

• The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Under in 31 of their last 50 away games (+10.15 Units / 17% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Moneyline in 21 of their last 40 games (+7.90 Units / 18% ROI)
• The Minnesota Twins have hit the Game Total Over in 14 of their last 22 games (+7.35 Units / 30% ROI)
• The Minnesota Twins have hit the Team Total Over in 22 of their last 35 games (+7.05 Units / 17% ROI)
• The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 24 of their last 40 games (+6.15 Units / 13% ROI)

Nationals Best Bets Today:

• The Washington Nationals have hit the 1st Five Innings (F5) Team Total Over in 31 of their last 45 games (+15.55 Units / 28% ROI)
• The Washington Nationals have hit the Team Total Over in 29 of their last 45 games (+10.70 Units / 20% ROI)
• The Washington Nationals have hit the Game Total Over in 21 of their last 35 games (+8.05 Units / 21% ROI)
• The Washington Nationals have covered the 1st Five Innings (F5) Run Line in 11 of their last 15 games (+6.40 Units / 34% ROI)
• The Washington Nationals have hit the Moneyline in 12 of their last 23 games (+5.90 Units / 26% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 17-18 against the Run Line (-7.75 Units / -15.2% ROI).

• 15-20 when betting on the Moneyline for -3.55 Units / -9.61% ROI
• 19-13 when betting on the total runs Over for +4.6 Units / 11.95% ROI
• 13-19 when betting on the total runs Under for -8 Units / -20.78% ROI

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 20-14 against the Run Line (+2.2 Units / 4.65% ROI).

• 16-19 when betting on the Moneyline for +4.15 Units / 11.76% ROI
• 21-12 when betting on the total runs Over for +8.05 Units / 21.05% ROI
• 12-21 when betting on the total runs Under for -11.25 Units / -28.99% ROI

Nationals vs Twins Home Run Prop Bets Today

Nationals vs Twins Total Hits Prop Bets Today

Nationals vs Twins Strikeout Prop Bets Today

Twins Keys to the Game vs. the Nationals

The Twins are just 6-23 (.207) when tied entering the 7th inning since the 2025 season — lowest in MLB; League Avg: .500.

The Twins are just 29-36 (.446) vs the bottom 10 runs allowed teams since the 2025 season Today, they face the Nationals (29th runs allowed).

The Twins are just 6-74 (.075) when trailing entering the 7th inning since the 2025 season — 3rd lowest in MLB; League Avg: .128.

The Twins are just 24-92 (.207) when scoring 4 or fewer runs since the 2025 season — 3rd lowest in MLB; League Avg: .284.

Nationals Keys to the Game vs. the Twins

The Nationals are just 35-61 (.361) at home since the 2025 season — 2nd lowest in MLB; League Avg: .541.

The Nationals are 8-2 (.800) when tied entering the 8th inning since the 2025 season — best in MLB; League Avg: .500.

The Nationals are just 13-51 (.200) when their opponents score in the first inning since the 2025 season — lowest in MLB; League Avg: .363.

The Nationals are just 4-12 (.250) at home this season — lowest in MLB; League Avg: .535.

Twins Hitting Stats & Trends

The Twins are batting just .194 with two outs this season — 3rd lowest in MLB.

The Twins are batting just .127 on pitches out of the zone since the 2025 season — 2nd lowest in MLB.

Twins hitters have chased 26% of pitches out of the zone against LHP this season — 3rd lowest in MLB.

Twins hitters have drawn walks in 12% of their PA’s against LHP this season — 4th best in MLB.

Nationals Hitting Stats & Trends

The Nationals are batting just .155 when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.

Nationals hitters are slugging just .250 when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.

Nationals hitters have an OPS of just .497 (166 PA’s) when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.

The Nationals are batting .276 against LHP this season — tied for 3rd best in MLB.

Twins Pitching Stats & Trends

Twins pitchers have a strikeout rate of just 20% this season — 5th lowest in MLB.

Opponents have a miss rate of just 22% against Twins pitchers this season — 3rd lowest in MLB.

Opponents have a groundball rate of just 39% against Twins pitchers since the 2025 season — 2nd lowest in MLB.

Twins pitchers have walked 8% of batters since the 2025 season — 4th best in MLB.

Nationals Pitching Stats & Trends

Nationals pitchers have an ERA of 5.44 (883.1 IP) at home since the 2025 season — 2nd highest in MLB.

Nationals pitchers have a strikeout rate of just 37% with two-strikes this season — 2nd lowest in MLB.

Nationals pitchers have an ERA of 5.25 (1740.2 IP) since the 2025 season — 2nd highest in MLB.

Nationals pitchers have a strikeout rate of just 19% this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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