- The Twins are -118 favorites vs the White Sox
- Twins vs White Sox Over / Under today: 8.5 Runs
- Twins / White Sox TV Channel: TWTV | CHSN
The Minnesota Twins (-118) visit Rate Field to take on the Chicago White Sox (-102) on May 25, 2026. First pitch is scheduled for 2:10 pm in Chicago, IL.
This season, the Twins are 26-27 against the spread (ATS), while the White Sox are 29-22 ATS.
Twins vs White Sox Starting Pitchers Today:
- Twins starting pitcher: Zebby Matthews 1-1, 1.39 ERA
- White Sox starting pitcher: Anthony Kay 3-1, 4.25 ERA
Twins vs. White Sox Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Twins | -1.5 +145 | O 8.5 -115 | -118 |
| White Sox | +1.5 -175 | U 8.5 -105 | -102 |
Twins vs White Sox Prediction for Today’s Game
Based on recent trends the model predicts the White Sox will win Monday‘s MLB game with 53.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Twins players for Monday‘s game, looking at profitable historical betting trends:
Best Twins Player Prop Bets Today:
- Byron Buxton has hit the Home Runs Over in 4 of his last 8 away games (+9.00 Units / 112% ROI)
- Byron Buxton has hit the Runs Over in 17 of his last 25 games (+9.00 Units / 33% ROI)
- Byron Buxton has hit the RBIs Over in 12 of his last 25 games (+8.40 Units / 34% ROI)
- Byron Buxton has hit the Hits Runs and RBIs Over in 17 of his last 25 games (+7.10 Units / 23% ROI)
- Byron Buxton has hit the Hits Over in 18 of his last 25 games (+6.60 Units / 13% ROI)
And here are some favorite MLB player prop bets for White Sox players for Monday‘s game, looking at profitable historical betting trends:
Best White Sox Player Prop Best Bets Today:
- Drew Romo has hit the Home Runs Over in 2 of his last 7 games at home (+14.00 Units / 200% ROI)
- Chase Meidroth has hit the Runs Over in 15 of his last 25 games at home (+12.25 Units / 49% ROI)
- Miguel Vargas has hit the Hits Over in 14 of his last 15 games at home (+12.10 Units / 41% ROI)
- Miguel Vargas has hit the Hits Runs and RBIs Over in 18 of his last 25 games at home (+11.30 Units / 41% ROI)
- Miguel Vargas has hit the RBIs Over in 7 of his last 10 games at home (+9.85 Units / 99% ROI)
Twins Best Bets Today:
- team high – away
White Sox Best Bets Today:
- team high – home
Twins Against the Spread (ATS) Record
Against the spread this season, the Twins are 30-23 against the Run Line (-2.45 Units / -3.23% ROI).
- 26-27 when betting on the Moneyline for -0.35 Units / -0.63% ROI
- 29-20 when betting on the total runs Over for +5.8 Units / 10.1% ROI
- 20-29 when betting on the total runs Under for -10.9 Units / -19.12% ROI
White Sox Against the Spread (ATS) Record
Against the spread this season, the White Sox are 29-22 against the Run Line (+0.3 Units / 0.4% ROI).
- 26-26 when betting on the Moneyline for +5.65 Units / 10.68% ROI
- 31-20 when betting on the total runs Over for +8.2 Units / 14.72% ROI
- 20-31 when betting on the total runs Under for -13.25 Units / -23.45% ROI
White Sox vs Twins Home Run Prop Bets Today
| Yes | |
|---|---|
| Byron Buxton | +200 |
| Munetaka Murakami | +200 |
| Colson Montgomery | +240 |
| Kody Clemens | +390 |
| Miguel Vargas | +425 |
White Sox vs Twins Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Sam Antonacci | 0.5 -250 | 0.5 +180 |
| Austin Martin | 0.5 -210 | 0.5 +155 |
| Chase Meidroth | 0.5 -190 | 0.5 +140 |
| Miguel Vargas | 0.5 -185 | 0.5 +135 |
| Munetaka Murakami | 0.5 -185 | 0.5 +135 |
White Sox vs Twins Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Kody Clemens | 0.5 -250 | 0.5 +185 |
| Victor Caratini | 0.5 -225 | 0.5 +165 |
| Drew Romo | 0.5 -210 | 0.5 +155 |
| Jared Kelenic | 0.5 -210 | 0.5 +155 |
| Ryan Kreidler | 0.5 -190 | 0.5 +140 |
Twins Keys to the Game vs. the White Sox
The Twins are just 0-20 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .105.
The Twins are just 0-23 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .053.
The Twins are just 2-5 (.286) when tied entering the 7th inning this season — tied for 4th lowest in MLB; League Avg: .500.
The Twins are just 7-24 (.226) when tied entering the 7th inning since the 2025 season — lowest in MLB; League Avg: .500.
White Sox Keys to the Game vs. the Twins
The White Sox are just 64-18 (.780) when leading entering the 7th inning since the 2025 season — lowest in MLB; League Avg: .872.
The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.
The White Sox are just 83-108 (.435) when allowing 5 or more extra base hits since the 2025 season — 2nd lowest in MLB; League Avg: .534.
The White Sox were just 41-121 (.253) in the 2024 season — lowest in MLB; League Avg: .500.
Twins Hitting Stats & Trends
Twins hitters have put just 31% of their swings in play on the first pitch of at-bats this season — 3rd lowest in MLB.
Twins hitters have a 54% QAB rate with runners in scoring position this season — best in MLB.
The Twins are batting just .286 on the first pitch of at-bats this season — 4th lowest in MLB.
Twins hitters have 29 extra-base hits out of 60 total hits (48%) on the first pitch of at-bats this season — best in MLB.
White Sox Hitting Stats & Trends
White Sox hitters are slugging .681 on the first pitch of at-bats this season — 2nd best in MLB.
White Sox hitters have struck out in 24% of their PA’s against RHP this season — 2nd highest in MLB.
White Sox hitters are slugging .445 against LHP this season — 3rd best in MLB.
The White Sox are batting just .127 on pitches out of the zone this season — 4th lowest in MLB.
Twins Pitching Stats & Trends
Opponents have a groundball rate of just 40% against Twins pitchers this season — tied for 2nd lowest in MLB.
Twins pitchers have a strikeout rate of just 18% in close and late situations this season — lowest in MLB.
Opponents have a miss rate of just 23% against Twins pitchers this season — 4th lowest in MLB.
Opponents have a groundball batting average of .282 against Twins pitchers with runners on base this season — 4th highest in MLB.
White Sox Pitching Stats & Trends
White Sox pitchers have walked 13% of batters when facing the leadoff batter in the inning this season — highest in MLB.
Opponents have a miss rate of just 23% against White Sox pitchers this season — 5th lowest in MLB.
White Sox pitchers have a strikeout rate of just 39% with two-strikes this season — tied for 5th lowest in MLB.
White Sox pitchers have allowed an exit velocity over 100 MPH 335 times this season — 5th most in MLB.
More MLB Reading:
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