Twins vs White Sox Prediction, Odds & Player Prop Bets Today – MLB, May 28

Chicago White Sox's Andrew Benintendi adjusts his helmet while standing on third base during the first inning of a spring training baseball game against the Texas Rangers in Phoenix, Monday, Feb. 26, 2024.
(AP Photo/Ashley Landis)
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The Minnesota Twins (+125) visit Rate Field to take on the Chicago White Sox (-150) on May 28, 2026. First pitch is scheduled for 2:10 pm in Chicago, IL.

This season, the Twins are 27-29 against the spread (ATS), while the White Sox are 31-23 ATS.

Twins vs White Sox Starting Pitchers Today:

  • Twins starting pitcher: Kendry Rojas 1-0, 1.29 ERA
  • White Sox starting pitcher: Davis Martin 7-1, 2.06 ERA

Twins vs. White Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Twins+1.5 -180O 8 -115+125
White Sox -1.5 +145U 8 -105-150

Twins vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Thursday‘s MLB game with 52.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Twins players for Thursday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

  • Victor Caratini has hit the Hits Under in 17 of his last 25 games (+15.25 Units / 61% ROI)
  • Victor Caratini has hit the Runs Under in his last 15 away games (+15.00 Units / 47% ROI)
  • Victor Caratini has hit the Hits Runs and RBIs Under in 20 of his last 25 games (+13.80 Units / 40% ROI)
  • Victor Caratini has hit the Total Bases Under in 17 of his last 25 games (+12.15 Units / 43% ROI)
  • Josh Bell has hit the Walks Under in 17 of his last 20 games (+11.35 Units / 28% ROI)

And here are some favorite MLB player prop bets for White Sox players for Thursday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

  • Drew Romo has hit the Home Runs Over in 3 of his last 9 games at home (+21.50 Units / 239% ROI)
  • Chase Meidroth has hit the Runs Over in 16 of his last 25 games (+15.40 Units / 62% ROI)
  • Chase Meidroth has hit the Total Bases Over in 19 of his last 25 games (+13.20 Units / 36% ROI)
  • Chase Meidroth has hit the Hits Runs and RBIs Over in 18 of his last 25 games (+12.75 Units / 49% ROI)
  • Luisangel Acuna has hit the Hits Under in 14 of his last 20 games (+11.75 Units / 59% ROI)
  • The Minnesota Twins have hit the Game Total Over in 27 of their last 45 games (+10.50 Units / 21% ROI)
  • The Minnesota Twins have covered the Run Line in 13 of their last 17 games (+9.50 Units / 40% ROI)
  • The Minnesota Twins have hit the Team Total Over in 31 of their last 50 games (+9.45 Units / 16% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Over in 30 of their last 50 games (+6.90 Units / 11% ROI)
  • The Minnesota Twins have hit the Moneyline in 11 of their last 17 games (+5.70 Units / 31% ROI)
  • The Chicago White Sox have hit the Team Total Over in 26 of their last 40 games (+10.10 Units / 22% ROI)
  • The Chicago White Sox have hit the Game Total Over in 25 of their last 40 games (+10.05 Units / 23% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 14 of their last 18 games (+9.85 Units / 44% ROI)
  • The Chicago White Sox have hit the Moneyline in 12 of their last 15 games at home (+9.60 Units / 61% ROI)
  • The Chicago White Sox have covered the Run Line in 23 of their last 35 games (+8.60 Units / 16% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 31-25 against the Run Line (-1.95 Units / -2.42% ROI).

  • 27-29 when betting on the Moneyline for -0.05 Units / -0.08% ROI
  • 31-21 when betting on the total runs Over for +7.8 Units / 12.63% ROI
  • 21-31 when betting on the total runs Under for -13.2 Units / -21.46% ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 31-23 against the Run Line (-1.35 Units / -1.66% ROI).

  • 28-27 when betting on the Moneyline for +5.6 Units / 9.8% ROI
  • 33-21 when betting on the total runs Over for +10.2 Units / 17% ROI
  • 21-33 when betting on the total runs Under for -15.55 Units / -25.49% ROI

White Sox vs Twins Home Run Prop Bets Today

Yes
Byron Buxton +230
Munetaka Murakami +270
Colson Montgomery +340
Kody Clemens +400
Miguel Vargas +425

White Sox vs Twins Total Hits Prop Bets Today

Over Under
Byron Buxton 0.5 -225 0.5 +165
Chase Meidroth 0.5 -220 0.5 +165
Josh Bell 0.5 -185 0.5 +135
Brooks Lee 0.5 -185 0.5 +135
Trevor Larnach 0.5 -185 0.5 +135

White Sox vs Twins Strikeout Prop Bets Today

Over Under
Kody Clemens 0.5 -235 0.5 +175
Derek Hill 0.5 -200 0.5 +150
Trevor Larnach 0.5 -200 0.5 +145
Josh Bell 0.5 -200 0.5 +150
Kendry Rojas 2.5 -190 2.5 +140

Twins Keys to the Game vs. the White Sox

The Twins are just 0-22 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .102.

The Twins are just 0-25 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .052.

The Twins are just 3-9 (.250) vs top 10 scoring offenses this season Today, they face the White Sox (12th in runs scored).

The Twins are just 7-24 (.226) when tied entering the 7th inning since the 2025 season — lowest in MLB; League Avg: .500.

White Sox Keys to the Game vs. the Twins

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

The White Sox are just 66-18 (.786) when leading entering the 7th inning since the 2025 season — 2nd lowest in MLB; League Avg: .872.

The White Sox were just 40-103 (.280) when allowing 5 or more extra base hits in the 2024 season — lowest in MLB; League Avg: .538.

The White Sox were just 41-121 (.253) in the 2024 season — lowest in MLB; League Avg: .500.

Twins hitters have 30 extra-base hits out of 63 total hits (48%) on the first pitch of at-bats this season — best in MLB.

Twins hitters have put just 32% of their swings in play on the first pitch of at-bats this season — tied for 2nd lowest in MLB.

The Twins are batting just .198 with two outs this season — lowest in MLB.

Twins have an xwOBA of just .348 this season — 2nd lowest in MLB.

White Sox hitters have struck out in 24% of their PA’s against RHP this season — 2nd highest in MLB.

White Sox hitters are slugging .422 at home this season — tied for 5th best in MLB.

White Sox hitters have missed on 28% of swings this season — highest in MLB.

White Sox hitters have an OPS of .788 (575 PA’s) against LHP this season — 4th best in MLB.

Opponents have a groundball rate of just 40% against Twins pitchers this season — 3rd lowest in MLB.

Opponents have a miss rate of just 23% against Twins pitchers this season — tied for 3rd lowest in MLB.

The longest HR allowed by the Twins pitchers this season traveled 474.2 feet — — 4th longest in MLB

Twins pitchers have an ERA of 5.20 (232.0 IP) on the road this season — 3rd highest in MLB.

White Sox pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — highest in MLB.

Opponents have a miss rate of just 23% against White Sox pitchers this season — tied for 3rd lowest in MLB.

White Sox pitchers have walked 10% of batters this season — tied for 5th highest in MLB.

White Sox pitchers have an ERA of 2.80 (90.0 IP) against division opponents this season — 4th best in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.