• The White Sox are -150 favorites vs the Twins
• Twins vs White Sox Over / Under today: 8.5 Runs
• Twins / White Sox TV Channel: PEAC

The Minnesota Twins (+125) visit Rate Field to take on the Chicago White Sox (-150) on September 6, 2026. First pitch is scheduled for 6:20 pm in Chicago, IL.

This season, the Twins are 68-74 against the spread (ATS), while the White Sox are 80-59 ATS.

Twins vs White Sox Starting Pitchers Today:

• Twins starting pitcher: Bailey Ober 7-4, 4.37 ERA
• White Sox starting pitcher: Bryan Hudson 4-4, 3.09 ERA

Twins vs. White Sox Odds, Run Line, Over/Under & Moneyline

Twins vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the White Sox will win Sunday‘s MLB game with 56.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Twins players for Sunday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

• Brooks Lee has hit the Home Runs Over in 4 of his last 9 away games (+23.90 Units / 266% ROI)
• Luke Keaschall has hit the Hits Over in 20 of his last 25 away games (+14.50 Units / 34% ROI)
• Kaelen Culpepper has hit the Total Bases Over in 17 of his last 20 games (+14.35 Units / 53% ROI)
• Royce Lewis has hit the Runs Under in 17 of his last 20 games (+11.80 Units / 37% ROI)
• Kody Clemens has hit the RBIs Over in 11 of his last 20 games (+8.75 Units / 44% ROI)

And here are some favorite MLB player prop bets for White Sox players for Sunday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

• Tristan Peters has hit the Home Runs Over in 5 of his last 7 games at home (+43.00 Units / 614% ROI)
• Miguel Vargas has hit the Hits Over in 21 of his last 25 games (+13.10 Units / 27% ROI)
• Munetaka Murakami has hit the Singles Under in 21 of his last 25 games (+12.70 Units / 25% ROI)
• Miguel Vargas has hit the Walks Over in 16 of his last 25 games (+12.65 Units / 50% ROI)
• Munetaka Murakami has hit the Hits Runs and RBIs Under in 13 of his last 15 games (+10.35 Units / 55% ROI)

Twins Best Bets Today:

• The Minnesota Twins have hit the Game Total Over in 30 of their last 50 away games (+13.25 Units / 24% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Over in 31 of their last 50 away games (+9.60 Units / 15% ROI)
• The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 12 of their last 18 games (+5.45 Units / 25% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Moneyline in 11 of their last 18 games (+4.95 Units / 23% ROI)
• The Minnesota Twins have hit the Team Total Over in 5 of their last 6 games (+4.05 Units / 58% ROI)

White Sox Best Bets Today:

• The Chicago White Sox have hit the Moneyline in 31 of their last 50 games at home (+11.30 Units / 19% ROI)
• The Chicago White Sox have covered the Run Line in 30 of their last 50 games at home (+10.30 Units / 15% ROI)
• The Chicago White Sox have hit the Game Total Over in 30 of their last 50 games at home (+8.85 Units / 16% ROI)
• The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 16 of their last 25 games (+6.10 Units / 19% ROI)
• The Chicago White Sox have hit the Team Total Over in 14 of their last 23 games at home (+4.30 Units / 16% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 76-65 against the Run Line (-5.35 Units / -2.66% ROI).

• 68-74 when betting on the Moneyline for -5.75 Units / -3.6% ROI
• 76-57 when betting on the total runs Over for +12.35 Units / 7.86% ROI
• 57-76 when betting on the total runs Under for -26.6 Units / -17.13% ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 80-59 against the Run Line (+6.3 Units / 3.13% ROI).

• 74-68 when betting on the Moneyline for +12.65 Units / 8.24% ROI
• 79-61 when betting on the total runs Over for +11.95 Units / 7.67% ROI
• 61-79 when betting on the total runs Under for -26.2 Units / -16.73% ROI

Twins Keys to the Game vs. the White Sox

The Twins are just 26-21 (.553) when they’ve hit 2 or more home runs this season — 2nd lowest in MLB.

The Twins are just 14-9 (.609) when they’ve had 5 or more XBH this season — 2nd lowest in MLB.

The Twins are just 5-11 (.312) when tied entering the 7th inning this season — 4th lowest in MLB.

The Twins are just 2-64 (.030) when trailing entering the 9th inning this season — 5th lowest in MLB.

White Sox Keys to the Game vs. the Twins

The White Sox are 14-5 (.737) when tied entering the 7th inning this season — 2nd best in MLB.

The White Sox are just 28-14 (.667) when they’ve had 10 or more hits this season — tied for 3rd lowest in MLB.

The White Sox are 23-26 (.469) when their opponents score in the first inning this season — 3rd best in MLB.

The White Sox are 42-28 (.600) at home this season — 5th best in MLB.

Twins Hitting Stats & Trends

The Twins are batting just .300 on the first pitch of at-bats this season — lowest in MLB.

Twins hitters have a 50% QAB rate with runners in scoring position this season — best in MLB.

Twins hitters have been successful in just 64% of their sacrifice bunt attempts this season — 2nd lowest in MLB.

Twins hitters have an OPS of .761 (1,634 PA’s) in righty-righty matchups this season — 3rd best in MLB.

White Sox Hitting Stats & Trends

White Sox hitters have 66 extra-base hits out of 136 total hits (48%) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

White Sox hitters have grounded into 64 double plays in 1,016 opportunities (6%) this season — best in MLB.

The White Sox are 43-19 (.694) against the run line (24.7% ROI) vs bottom 10 scoring offenses this season Today, they face the Twins (eighth in runs scored).

White Sox hitters have 127 extra-base hits out of 322 total hits (39%) against LHP this season — best in MLB.

Twins Pitching Stats & Trends

Twins pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — tied for 2nd highest in MLB.

The Twins have allowed 5.44 runs per game (381/70) on the road this season — highest in MLB.

Twins pitchers have allowed innings of 3+ runs in 7% of innings played this season — tied for 3rd highest in MLB.

Twins pitchers have allowed an OBP of .337 (1,256 PA’s) when facing the leadoff batter in the inning this season — tied for 3rd highest in MLB.

White Sox Pitching Stats & Trends

White Sox pitchers have an ERA of 3.25 (365.1 IP) against division opponents this season — 2nd best in MLB.

White Sox pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 5th highest in MLB.

Opponents have a groundball rate of just 40% against White Sox pitchers this season — tied for 3rd lowest in MLB.

The White Sox have won 50% of home games in which their opponents scored first this season — 2nd highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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