• The Astros are -145 favorites vs the White Sox
• White Sox vs Astros Over / Under today: 8.5 Runs
• White Sox / Astros TV Channel: CHSN | SCHN

The Chicago White Sox (+118) visit Daikin Park to take on the Houston Astros (-145) on September 2, 2026. First pitch is scheduled for 8:10 pm in Houston, TX.

This season, the White Sox are against the spread (ATS), while the Astros are ATS.

White Sox vs Astros Starting Pitchers Today:

• White Sox starting pitcher: Davis Martin 9-6, 4.34 ERA
• Astros starting pitcher: Hayden Wesneski 4-1, 3.86 ERA

White Sox vs. Astros Odds, Run Line, Over/Under & Moneyline

White Sox vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Wednesday‘s MLB game with 57.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on White Sox vs Astros and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for White Sox players for Wednesday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

• Tristan Peters has hit the Home Runs Over in 5 of his last 10 games (+40.00 Units / 400% ROI)
• Miguel Vargas has hit the Walks Over in 19 of his last 25 games (+21.00 Units / 84% ROI)
• Munetaka Murakami has hit the Singles Under in 22 of his last 25 games (+15.80 Units / 31% ROI)
• Sam Antonacci has hit the Hits Under in 13 of his last 20 away games (+14.50 Units / 73% ROI)
• Sam Antonacci has hit the Total Bases Under in 17 of his last 20 away games (+11.50 Units / 34% ROI)

And here are some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

• Cam Smith has hit the Singles Under in 14 of his last 15 games (+12.70 Units / 57% ROI)
• Christian Walker has hit the Total Bases Under in 15 of his last 20 games (+12.20 Units / 50% ROI)
• Jeremy Pena has hit the Home Runs Over in 3 of his last 8 games (+11.50 Units / 144% ROI)
• Cam Smith has hit the Hits Under in 11 of his last 15 games (+10.45 Units / 70% ROI)
• Taylor Trammell has hit the Runs Under in his last 10 games (+10.00 Units / 45% ROI)

White Sox Best Bets Today:

• The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 29 of their last 45 away games (+11.55 Units / 21% ROI)
• The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 23 of their last 35 away games (+8.70 Units / 21% ROI)
• The Chicago White Sox have covered the Run Line in 20 of their last 30 away games (+8.25 Units / 19% ROI)
• The Chicago White Sox have hit the Moneyline in 15 of their last 25 away games (+6.95 Units / 27% ROI)
• The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 14 of their last 30 away games (+5.75 Units / 18% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 16 of their last 22 games (+8.50 Units / 31% ROI)
• The Houston Astros have hit the Team Total Under in 7 of their last 9 games at home (+5.05 Units / 51% ROI)
• The Houston Astros have covered the Run Line in 21 of their last 40 games (+4.15 Units / 8% ROI)
• The Houston Astros have hit the Game Total Under in 6 of their last 9 games at home (+2.70 Units / 27% ROI)
• The Houston Astros have hit the Moneyline in 5 of their last 8 games (+2.65 Units / 31% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Astros vs White Sox Home Run Prop Bets Today

Astros vs White Sox Total Hits Prop Bets Today

Astros vs White Sox Strikeout Prop Bets Today

White Sox Keys to the Game vs. the Astros

The White Sox are 23-25 (.479) when their opponents score in the first inning this season — 3rd best in MLB.

The White Sox are 14-4 (.778) when tied entering the 7th inning this season — 2nd best in MLB.

The White Sox are 38-27 (.585) after a loss this season — tied for 3rd best in MLB.

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

Astros Keys to the Game vs. the White Sox

The Astros are 11-5 (.688) when tied entering the 8th inning this season — 3rd best in MLB.

The Astros are 60-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB.

The Astros are 52-3 (.945) when leading entering the 7th inning this season — 2nd best in MLB.

The Astros are 21-10 (.677) when tied entering the 8th inning since the 2025 season — best in MLB.

White Sox Hitting Stats & Trends

White Sox hitters have 66 extra-base hits out of 135 total hits (49%) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

White Sox hitters have 126 extra-base hits out of 320 total hits (39%) against LHP this season — best in MLB.

White Sox hitters are slugging .610 on the first pitch of at-bats this season — 2nd best in MLB.

The White Sox have a winning percentage of 60% at home this season — 5th best in MLB.

Astros Hitting Stats & Trends

Astros hitters have drawn walks in 13% of their PA’s with runners in scoring position this season — best in MLB.

Astros hitters have an OBP of just .237 (2,756 PA’s) with two-strikes this season — tied for 4th lowest in MLB.

Astros hitters have 42 extra-base hits out of 154 total hits (just 27%) when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB.

29% of Astros hitters strikeouts have come on 95+ MPH fastballs this season — tied for 2nd highest in MLB.

White Sox Pitching Stats & Trends

Opponents have a groundball rate of just 40% against White Sox pitchers this season — 4th lowest in MLB.

White Sox pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 4th highest in MLB.

The White Sox have won 50% of home games in which their opponents scored first this season — 2nd highest in MLB.

The White Sox pitchers have allowed their opponents to score first in just 39% of their games on the road this season — 4th lowest in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 11% of batters when facing the leadoff batter in the inning this season — highest in MLB.

Astros pitchers have walked 11% of batters this season — highest in MLB.

Opponents have a groundball rate of just 39% against Astros pitchers this season — 2nd lowest in MLB.

The Astros have allowed 3.14 runs per game (437/139) in the first 5 innings this season — 3rd highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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