White Sox vs Cubs Prediction, Odds & Player Prop Bets Today – MLB, Aug 17

Chicago Cubs' Ian Happ watches his grand slam off Pittsburgh Pirates starting pitcher Mitch Keller during the fifth inning of a baseball game Wednesday, Sept. 20, 2023, in Chicago. (AP Photo/Charles Rex Arbogast)
(AP Photo/Charles Rex Arbogast)
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The Chicago White Sox (+140) visit Wrigley Field to take on the Chicago Cubs (-170) on August 17, 2026. First pitch is scheduled for 8:05 pm in Chicago, IL.

This season, the White Sox are against the spread (ATS), while the Cubs are ATS.

White Sox vs Cubs Starting Pitchers Today:

  • White Sox starting pitcher: Luis Castillo 4-9, 4.98 ERA
  • Cubs starting pitcher: Shota Imanaga 8-9, 3.74 ERA

White Sox vs. Cubs Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox+1.5 -155O 8 -105+140
Cubs -1.5 +125U 8 -115-170

White Sox vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Monday‘s MLB game with 56.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for White Sox players for Monday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

  • Chase Meidroth has hit the Home Runs Over in 2 of his last 8 games (+15.00 Units / 188% ROI)
  • Sam Antonacci has hit the Hits Under in 10 of his last 15 away games (+12.20 Units / 81% ROI)
  • Randal Grichuk has hit the Total Bases Over in 16 of his last 25 games (+10.35 Units / 35% ROI)
  • Miguel Vargas has hit the Singles Under in 19 of his last 25 away games (+10.05 Units / 28% ROI)
  • Jake Rogers has hit the Hits Runs and RBIs Under in 9 of his last 10 away games (+9.20 Units / 92% ROI)

And here are some favorite MLB player prop bets for Cubs players for Monday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

  • Nico Hoerner has hit the Home Runs Over in 2 of his last 9 games at home (+21.00 Units / 233% ROI)
  • Seiya Suzuki has hit the Total Bases Over in 18 of his last 25 games at home (+12.50 Units / 44% ROI)
  • Seiya Suzuki has hit the Hits Over in 20 of his last 25 games at home (+12.45 Units / 25% ROI)
  • Seiya Suzuki has hit the Hits Runs and RBIs Over in 19 of his last 25 games at home (+12.40 Units / 41% ROI)
  • Nico Hoerner has hit the Singles Over in 19 of his last 25 games (+10.25 Units / 27% ROI)
  • The Chicago White Sox have covered the Run Line in 30 of their last 50 games (+10.35 Units / 15% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 25 of their last 40 away games (+8.30 Units / 17% ROI)
  • The Chicago White Sox have hit the Team Total Over in 30 of their last 50 away games (+8.10 Units / 14% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 17 of their last 25 away games (+7.55 Units / 25% ROI)
  • The Chicago White Sox have hit the Moneyline in 11 of their last 17 away games (+6.55 Units / 37% ROI)
  • The Chicago Cubs have covered the Run Line in 32 of their last 50 games (+21.45 Units / 37% ROI)
  • The Chicago Cubs have hit the Moneyline in 33 of their last 50 games (+11.65 Units / 18% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Under in 28 of their last 45 games at home (+9.15 Units / 17% ROI)
  • The Chicago Cubs have hit the Team Total Over in 31 of their last 50 games (+8.10 Units / 13% ROI)
  • The Chicago Cubs have hit the Game Total Over in 29 of their last 50 games (+7.05 Units / 13% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are against the Run Line ( Units / ROI).

  • away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • away total over record when betting on the total runs Over for over units Units / over ROI ROI
  • away total under record when betting on the total runs Under for under units Units / under ROI ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are against the Run Line ( Units / ROI).

  • home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • home total over record when betting on the total runs Over for over units Units / over ROI ROI
  • home total under record when betting on the total runs Under for under units Units / under ROI ROI

Cubs vs White Sox Home Run Prop Bets Today

Yes
Pete Crow-Armstrong +250
Munetaka Murakami +270
Miguel Vargas +280
Colson Montgomery +310
Mike Busch +340

Cubs vs White Sox Total Hits Prop Bets Today

Over Under
Pete Crow-Armstrong 0.5 -250 0.5 +180
Chase Meidroth 0.5 -235 0.5 +175
Seiya Suzuki 0.5 -225 0.5 +165
Mike Busch 0.5 -225 0.5 +165
Nico Hoerner 0.5 -225 0.5 +165

Cubs vs White Sox Strikeout Prop Bets Today

Over Under
Jake Rogers 0.5 -275 0.5 +200
Brenton Doyle 0.5 -275 0.5 +200
Mike Busch 0.5 -225 0.5 +165
Chase Meidroth 0.5 -200 0.5 +150
Munetaka Murakami 1.5 -190 1.5 +140

White Sox Keys to the Game vs. the Cubs

The White Sox were just 4-40 (.091) when their opponents score in the first inning in the 2024 season — lowest in MLB; League Avg: .359.

The White Sox were just 35-12 (.745) when leading entering the 8th inning in the 2024 season — lowest in MLB; League Avg: .899.

The White Sox were just 3-58 (.049) when allowing 10 or more hits in the 2024 season — lowest in MLB; League Avg: .250.

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

Cubs Keys to the Game vs. the White Sox

The Cubs are 5-3 (.625) after a win this season — tied for 4th best in MLB.

The Cubs are 5-3 (.625) after a win since the 2025 season — tied for 4th best in MLB.

The Cubs were 48-6 (.889) when they had 10 or more hits in the 2025 season — best in MLB; League Avg: .743.

The Cubs were 40-9 (.816) when they scored in the first inning in the 2025 season — best in MLB; League Avg: .636.

White Sox hitters have 61 extra-base hits out of 125 total hits (49%) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

White Sox hitters are slugging .506 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

White Sox hitters have grounded into 56 double plays in 871 opportunities (6%) this season — best in MLB.

29% of White Sox hitters strikeouts have come on 95+ MPH fastballs this season — 3rd highest in MLB.

Cubs hitters have an OBP of .355 (1,328 PA’s) against LHP this season — best in MLB.

Cubs hitters have an OPS of .800 (1,328 PA’s) against LHP this season — best in MLB.

The Cubs are batting .268 against LHP this season — 2nd best in MLB.

Cubs hitters are slugging .445 against LHP this season — 2nd best in MLB.

The White Sox have won 53% of home games in which their opponents scored first this season — 2nd highest in MLB.

White Sox pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 4th highest in MLB.

Opponents have a groundball rate of just 40% against White Sox pitchers this season — 4th lowest in MLB.

White Sox pitchers have an ERA of 3.38 (565.0 IP) at home this season — 3rd best in MLB.

Opponents have a groundball batting average of just .209 against Cubs pitchers with runners on base this season — best in MLB.

Cubs pitchers have walked 8% of batters this season — 5th best in MLB.

Cubs pitchers have won 37% of games in which they have allowed their opponent to score in three different innings this season — highest in MLB.

Cubs pitchers have picked-off 19 runners from first base this season — most in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.