• The Phillies are -190 favorites vs the White Sox
• White Sox vs Phillies Over / Under today: 8.5 Runs
• White Sox / Phillies TV Channel: CHSN | NSPA

The Chicago White Sox (+154) visit Citizens Bank Park to take on the Philadelphia Phillies (-190) on June 5, 2026. First pitch is scheduled for 6:40 pm in Philadelphia, PA.

This season, the White Sox are 33-29 against the spread (ATS), while the Phillies are 20-41 ATS.

White Sox vs Phillies Starting Pitchers Today:

• White Sox starting pitcher: Anthony Kay 5-1, 3.77 ERA
• Phillies starting pitcher: Jesus Luzardo 4-4, 4.28 ERA

White Sox vs. Phillies Odds, Run Line, Over/Under & Moneyline

White Sox vs Phillies Prediction for Today’s Game

Based on recent trends the model predicts the Phillies will win Friday‘s MLB game with 61.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on White Sox vs Phillies and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for White Sox players for Friday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

• Chase Meidroth has hit the Runs Over in 15 of his last 20 away games (+17.40 Units / 87% ROI)
• Chase Meidroth has hit the Hits Over in 18 of his last 20 away games (+16.90 Units / 48% ROI)
• Chase Meidroth has hit the Hits Runs and RBIs Over in 17 of his last 20 away games (+15.55 Units / 71% ROI)
• Chase Meidroth has hit the Total Bases Over in 16 of his last 20 away games (+13.75 Units / 50% ROI)
• Drew Romo has hit the Singles Under in 17 of his last 20 games (+11.70 Units / 33% ROI)

And here are some favorite MLB player prop bets for Phillies players for Friday‘s game, looking at profitable historical betting trends:

Best Phillies Player Prop Best Bets Today:

• Bryce Harper has hit the Hits Under in 15 of his last 25 games (+13.00 Units / 42% ROI)
• Bryce Harper has hit the Singles Under in 19 of his last 25 games (+11.05 Units / 35% ROI)
• J.T. Realmuto has hit the Home Runs Over in 2 of his last 7 games (+10.90 Units / 156% ROI)
• Bryson Stott has hit the Total Bases Over in 15 of his last 20 games at home (+10.50 Units / 37% ROI)
• Alec Bohm has hit the Runs Under in 19 of his last 25 games at home (+8.60 Units / 19% ROI)

White Sox Best Bets Today:

• The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 19 of their last 25 games (+13.00 Units / 42% ROI)
• The Chicago White Sox have hit the Moneyline in 25 of their last 40 games (+11.40 Units / 26% ROI)
• The Chicago White Sox have hit the Team Total Over in 29 of their last 45 games (+10.70 Units / 20% ROI)
• The Chicago White Sox have hit the Game Total Over in 15 of their last 22 games (+9.55 Units / 40% ROI)
• The Chicago White Sox have covered the Run Line in 23 of their last 35 games (+8.70 Units / 17% ROI)

Phillies Best Bets Today:

• The Philadelphia Phillies have hit the 1st Five Innings (F5) Team Total Under in 30 of their last 45 games (+14.00 Units / 26% ROI)
• The Philadelphia Phillies have hit the Game Total Under in 18 of their last 22 games (+13.60 Units / 56% ROI)
• The Philadelphia Phillies have hit the Moneyline in 24 of their last 35 games (+10.00 Units / 20% ROI)
• The Philadelphia Phillies have hit the Team Total Under in 26 of their last 40 games at home (+9.30 Units / 19% ROI)
• The Philadelphia Phillies have hit the 1st Five Innings (F5) Moneyline in 3 of their last 5 games at home (+1.80 Units / 17% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 35-26 against the Run Line (-0.85 Units / -0.94% ROI).

• 33-29 when betting on the Moneyline for +8.6 Units / 13.1% ROI
• 36-24 when betting on the total runs Over for +9.8 Units / 14.46% ROI
• 24-36 when betting on the total runs Under for -15.9 Units / -23.16% ROI

Phillies Against the Spread (ATS) Record

Against the spread this season, the Phillies are 20-41 against the Run Line (-24.45 Units / -33.31% ROI).

• 33-29 when betting on the Moneyline for -4.45 Units / -4.95% ROI
• 26-34 when betting on the total runs Over for -11.2 Units / -16.4% ROI
• 34-26 when betting on the total runs Under for +5.7 Units / 8.36% ROI

Phillies vs White Sox Home Run Prop Bets Today

Phillies vs White Sox Total Hits Prop Bets Today

Phillies vs White Sox Strikeout Prop Bets Today

White Sox Keys to the Game vs. the Phillies

The White Sox are 6-22 (.214) when trailing entering the 7th inning this season — 5th best in MLB; League Avg: .142.

The White Sox are 3-24 (.111) when trailing entering the 9th inning this season — tied for 4th best in MLB; League Avg: .055.

The White Sox were just 41-121 (.253) in the 2024 season — lowest in MLB; League Avg: .500.

The White Sox are just 8-19 (.296) when tied entering the 8th inning since the 2025 season — 2nd lowest in MLB; League Avg: .500.

Phillies Keys to the Game vs. the White Sox

The Phillies are 24-1 (.960) when leading entering the 7th inning this season — tied for 2nd best in MLB; League Avg: .858.

The Phillies are 6-0 (1.000) when they’ve had 5 or more XBH this season — tied for best in MLB; League Avg: .781.

The Phillies are 28-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB; League Avg: .945.

The Phillies are 6-27 (.182) when trailing entering the 8th inning this season — tied for 3rd best in MLB; League Avg: .107.

White Sox Hitting Stats & Trends

White Sox hitters have struck out in 24% of their PA’s against RHP this season — 3rd highest in MLB.

White Sox hitters have an OPS of .756 (1,159 PA’s) at home this season — 5th best in MLB.

White Sox hitters have an OPS of .749 (738 PA’s) in innings 7-9 this season — 4th best in MLB.

White Sox hitters are slugging .673 on the first pitch of at-bats this season — 2nd best in MLB.

Phillies Hitting Stats & Trends

Phillies hitters have an OBP of just .273 (1,085 PA’s) on the road this season — lowest in MLB.

Phillies hitters have an OBP of just .295 (1,603 PA’s) against RHP this season — tied for lowest in MLB.

The Phillies are batting just .207 on the road this season — lowest in MLB.

The Phillies are batting just .211 against LHP this season — 2nd lowest in MLB.

White Sox Pitching Stats & Trends

White Sox pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — 2nd highest in MLB.

White Sox pitchers have a strikeout rate of just 20% in the first 5 innings this season — 5th lowest in MLB.

White Sox pitchers have an ERA of 5.12 (263.2 IP) on the road this season — 5th highest in MLB.

White Sox pitchers have an ERA of 2.90 (152.0 IP) against division opponents this season — 5th best in MLB.

Phillies Pitching Stats & Trends

Phillies pitchers have allowed an average Exit Velocity of 87.5 MPH (1,527 batted balls) this season — best in MLB.

Phillies pitchers have a strikeout rate of 47% with two-strikes this season — best in MLB.

Opponents have a groundball batting average of .285 against Phillies pitchers this season — highest in MLB.

Opponents have a groundball rate of 46% against Phillies pitchers this season — 5th highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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