• The White Sox are -105 favorites vs the Tigers
• White Sox vs Tigers Over / Under today: 8.5 Runs
• White Sox / Tigers TV Channel: CHSN | DSN

The Chicago White Sox (-105) visit Comerica Park to take on the Detroit Tigers (-115) on June 21, 2026. First pitch is scheduled for 1:40 pm in Detroit, MI.

This season, the White Sox are 39-36 against the spread (ATS), while the Tigers are 32-40 ATS.

White Sox vs Tigers Starting Pitchers Today:

• White Sox starting pitcher: Davis Martin 9-3, 3.32 ERA
• Tigers starting pitcher: Keider Montero 3-5, 3.69 ERA

White Sox vs. Tigers Odds, Run Line, Over/Under & Moneyline

White Sox vs Tigers Prediction for Today’s Game

Based on recent trends the model predicts the Tigers will win Sunday‘s MLB game with 52.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on White Sox vs Tigers and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for White Sox players for Sunday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

• Sam Antonacci has hit the Home Runs Over in 3 of his last 5 games (+27.00 Units / 540% ROI)
• Edgar Quero has hit the Hits Under in 13 of his last 20 away games (+10.90 Units / 55% ROI)
• Edgar Quero has hit the Total Bases Under in 14 of his last 20 away games (+10.40 Units / 42% ROI)
• Tristan Peters has hit the Hits Runs and RBIs Over in 15 of his last 20 away games (+10.00 Units / 38% ROI)
• Andrew Benintendi has hit the Runs Over in 14 of his last 25 games (+9.80 Units / 39% ROI)

And here are some favorite MLB player prop bets for Tigers players for Sunday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Best Bets Today:

• Colt Keith has hit the Home Runs Over in 2 of his last 5 games (+14.00 Units / 280% ROI)
• Kevin McGonigle has hit the Hits Over in 20 of his last 25 games (+10.40 Units / 20% ROI)
• Dillon Dingler has hit the RBIs Over in 13 of his last 25 games (+10.00 Units / 40% ROI)
• Colt Keith has hit the Hits Runs and RBIs Under in 18 of his last 25 games (+9.30 Units / 27% ROI)
• Spencer Torkelson has hit the Singles Under in his last 9 games (+9.00 Units / 50% ROI)

White Sox Best Bets Today:

• The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 25 of their last 35 games (+14.60 Units / 34% ROI)
• The Chicago White Sox have hit the Moneyline in 29 of their last 50 games (+11.05 Units / 21% ROI)
• The Chicago White Sox have hit the Game Total Over in 22 of their last 35 games (+9.90 Units / 26% ROI)
• The Chicago White Sox have hit the Team Total Over in 31 of their last 50 games (+9.85 Units / 17% ROI)
• The Chicago White Sox have covered the Run Line in 28 of their last 45 games (+6.50 Units / 10% ROI)

Tigers Best Bets Today:

• The Detroit Tigers have hit the Team Total Under in 26 of their last 40 games (+10.20 Units / 22% ROI)
• The Detroit Tigers have hit the Game Total Under in 25 of their last 45 games (+5.50 Units / 11% ROI)
• The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Under in 6 of their last 7 games (+4.80 Units / 52% ROI)
• The Detroit Tigers have hit the 1st Five Innings (F5) Moneyline in 13 of their last 24 games (+4.45 Units / 15% ROI)
• The Detroit Tigers have hit the Moneyline in 10 of their last 16 games (+3.55 Units / 18% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 42-32 against the Run Line (-2.05 Units / -1.89% ROI).

• 39-36 when betting on the Moneyline for +9.75 Units / 12.4% ROI
• 43-30 when betting on the total runs Over for +10.15 Units / 12.36% ROI
• 30-43 when betting on the total runs Under for -17.6 Units / -21.23% ROI

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 32-40 against the Run Line (-11.65 Units / -11.79% ROI).

• 32-44 when betting on the Moneyline for -17.7 Units / -19.35% ROI
• 33-39 when betting on the total runs Over for -9.7 Units / -11.56% ROI
• 39-33 when betting on the total runs Under for +3.15 Units / 3.78% ROI

Tigers vs White Sox Home Run Prop Bets Today

Tigers vs White Sox Total Hits Prop Bets Today

Tigers vs White Sox Strikeout Prop Bets Today

White Sox Keys to the Game vs. the Tigers

The White Sox are just 3-18 (.143) when allowing 10 or more hits this season — tied for 4th lowest in MLB; League Avg: .248.

The White Sox are 7-29 (.194) when trailing entering the 7th inning this season — 5th best in MLB; League Avg: .138.

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

The White Sox are just 28-115 (.196) when scoring 4 or fewer runs since the 2025 season — 2nd lowest in MLB; League Avg: .282.

Tigers Keys to the Game vs. the White Sox

The Tigers are just 25-11 (.694) when leading entering the 7th inning this season — lowest in MLB; League Avg: .862.

The Tigers are just 3-23 (.115) when allowing 5 or more runs this season — 2nd lowest in MLB; League Avg: .207.

The Tigers are just 24-7 (.774) when leading entering the 8th inning this season — 2nd lowest in MLB; League Avg: .896.

The Tigers are just 2-6 (.250) when tied entering the 8th inning this season — 3rd lowest in MLB; League Avg: .500.

White Sox Hitting Stats & Trends

White Sox hitters are slugging .437 against LHP this season — 4th best in MLB.

White Sox hitters have grounded into 38 double plays in 535 opportunities (7%) this season — 3rd best in MLB.

White Sox hitters have put just 31% of their swings in play in lefty-lefty matchups this season — lowest in MLB.

White Sox hitters have an OPS of .764 (827 PA’s) against LHP this season — 5th best in MLB.

Tigers Hitting Stats & Trends

Tigers hitters have drawn walks in 13% of their PA’s against LHP this season — best in MLB.

The Tigers are batting just .218 against LHP this season — tied for 2nd lowest in MLB.

Tigers hitters have chased 25% of pitches out of the zone against LHP this season — lowest in MLB.

Tigers hitters have chased 12% of pitches out of the zone on the first pitch of at-bats this season — lowest in MLB.

White Sox Pitching Stats & Trends

White Sox pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — 2nd highest in MLB.

White Sox pitchers have an ERA of 5.43 (329.2 IP) on the road this season — 2nd highest in MLB.

White Sox pitchers have walked 10% of batters this season — tied for 5th highest in MLB.

White Sox pitchers have an ERA of 3.41 (333.0 IP) at home this season — 5th best in MLB.

Tigers Pitching Stats & Trends

Tigers pitchers have 93 three-pitch strikeouts this season — tied for 4th fewest in MLB.

Tigers pitchers have allowed 74 home runs this season — tied for 4th fewest in MLB.

Tigers pitchers have induced opposing hitters to ground into 56 double plays in 535 opportunities (10%) this season — 5th best in MLB.

Tigers pitchers have 93 three-pitch strikeouts this season — tied for 4th fewest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

Bet now on White Sox vs Tigers and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.