• The Twins are -135 favorites vs the White Sox
• White Sox vs Twins Over / Under today: 8.5 Runs
• White Sox / Twins TV Channel: TWTV | CHSN

The Chicago White Sox (+110) visit Target Field to take on the Minnesota Twins (-135) on August 28, 2026. First pitch is scheduled for 8:10 pm in Minneapolis, MN.

This season, the White Sox are 70-63 against the spread (ATS), while the Twins are 71-62 ATS.

White Sox vs Twins Starting Pitchers Today:

• White Sox starting pitcher: Luis Castillo 4-10, 5.21 ERA
• Twins starting pitcher: Dean Kremer 2-4, 5.28 ERA

White Sox vs. Twins Odds, Run Line, Over/Under & Moneyline

White Sox vs Twins Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Friday‘s MLB game with 51.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on White Sox vs Twins and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for White Sox players for Friday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

• Tristan Peters has hit the Home Runs Over in his last 5 games (+45.00 Units / 900% ROI)
• Miguel Vargas has hit the Walks Over in 15 of his last 20 games (+17.35 Units / 87% ROI)
• Munetaka Murakami has hit the Singles Under in 18 of his last 20 games (+13.75 Units / 34% ROI)
• Sam Antonacci has hit the Hits Under in 10 of his last 15 away games (+11.30 Units / 75% ROI)
• Tristan Peters has hit the Runs Over in his last 5 games (+9.65 Units / 193% ROI)

And here are some favorite MLB player prop bets for Twins players for Friday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Best Bets Today:

• Brooks Lee has hit the Home Runs Over in 4 of his last 10 games (+23.40 Units / 234% ROI)
• Ryan Jeffers has hit the Hits Over in 21 of his last 25 games at home (+13.35 Units / 26% ROI)
• Josh Bell has hit the Runs Over in 15 of his last 25 games (+10.05 Units / 39% ROI)
• Kaelen Culpepper has hit the Singles Over in his last 7 games at home (+9.40 Units / 134% ROI)
• Kaelen Culpepper has hit the Total Bases Over in 9 of his last 10 games (+8.55 Units / 70% ROI)

White Sox Best Bets Today:

• The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 26 of their last 40 away games (+10.40 Units / 21% ROI)
• The Chicago White Sox have covered the Run Line in 16 of their last 21 away games (+10.10 Units / 32% ROI)
• The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 20 of their last 30 away games (+8.35 Units / 23% ROI)
• The Chicago White Sox have hit the Game Total Over in 15 of their last 23 games (+6.10 Units / 24% ROI)
• The Chicago White Sox have hit the Moneyline in 12 of their last 20 away games (+5.80 Units / 28% ROI)

Twins Best Bets Today:

• The Minnesota Twins have hit the Game Total Under in 15 of their last 22 games at home (+7.25 Units / 30% ROI)
• The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 8 of their last 10 games (+5.80 Units / 49% ROI)
• The Minnesota Twins have hit the Team Total Under in 24 of their last 40 games (+5.60 Units / 12% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Moneyline in 7 of their last 10 games (+4.65 Units / 40% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Under in 21 of their last 35 games at home (+4.45 Units / 11% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 77-53 against the Run Line (+10.3 Units / 5.43% ROI).

• 70-63 when betting on the Moneyline for +13.75 Units / 9.57% ROI
• 76-55 when betting on the total runs Over for +15.75 Units / 10.81% ROI
• 55-76 when betting on the total runs Under for -28.95 Units / -19.71% ROI

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 71-62 against the Run Line (-7.1 Units / -3.76% ROI).

• 64-70 when betting on the Moneyline for -5.15 Units / -3.43% ROI
• 71-54 when betting on the total runs Over for +10.85 Units / 7.32% ROI
• 54-71 when betting on the total runs Under for -24.1 Units / -16.44% ROI

Twins vs White Sox Home Run Prop Bets Today

Twins vs White Sox Total Hits Prop Bets Today

Twins vs White Sox Strikeout Prop Bets Today

White Sox Keys to the Game vs. the Twins

The White Sox are 14-4 (.778) when tied entering the 7th inning this season — 2nd best in MLB.

The White Sox are 37-26 (.587) after a loss this season — 3rd best in MLB.

The White Sox are just 143-100 (.588) when allowing 4 or fewer runs since the 2024 season — lowest in MLB.

The White Sox are just 128-47 (.731) when leading entering the 7th inning since the 2024 season — lowest in MLB.

Twins Keys to the Game vs. the White Sox

The Twins are just 12-9 (.571) when they’ve had 5 or more XBH this season — lowest in MLB.

The Twins are just 24-20 (.545) when they’ve hit 2 or more home runs this season — 2nd lowest in MLB.

The Twins are just 5-11 (.312) when tied entering the 7th inning this season — 5th lowest in MLB.

The Twins are just 14-32 (.304) when their opponents score in the first inning this season — 5th lowest in MLB.

White Sox Hitting Stats & Trends

White Sox hitters have 65 extra-base hits out of 133 total hits (49%) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

White Sox hitters are slugging .421 against LHP this season — 5th best in MLB.

The White Sox are 43-19 (.694) against the run line (24.7% ROI) vs bottom 10 scoring offenses this season Today, they face the Twins (ninth in runs scored).

White Sox hitters have an OBP of .345 (578 PA’s) when facing the starting pitcher for the 3rd time in a game this season — 4th best in MLB.

Twins Hitting Stats & Trends

The Twins are batting just .296 on the first pitch of at-bats this season — lowest in MLB.

Twins hitters have a 51% QAB rate with runners in scoring position this season — best in MLB.

The Twins are batting just .220 with two outs this season — 2nd lowest in MLB.

Twins hitters have 77 extra-base hits out of 174 total hits (44%) on the first pitch of at-bats this season — best in MLB.

White Sox Pitching Stats & Trends

White Sox pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 5th highest in MLB.

The White Sox have won 50% of home games in which their opponents scored first this season — 2nd highest in MLB.

The White Sox pitchers have allowed their opponents to score first in just 39% of their games on the road this season — 4th lowest in MLB.

White Sox pitchers have an ERA of 3.19 (321.1 IP) against division opponents this season — 4th best in MLB.

Twins Pitching Stats & Trends

Twins pitchers have an ERA of 5.19 (583.0 IP) on the road this season — highest in MLB.

Twins pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — tied for 2nd highest in MLB.

The Twins have allowed 5.49 runs per game (373/68) on the road this season — highest in MLB.

Twins pitchers have an ERA of 4.69 (1180.1 IP) this season — tied for 4th highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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