• The Yankees are -115 favorites vs the Padres
• Yankees vs Padres Over / Under today: 7 Runs
• Yankees / Padres TV Channel: PDTV | YES

The New York Yankees (-115) visit Petco Park to take on the San Diego Padres (-105) on September 6, 2026. First pitch is scheduled for 4:10 pm in San Diego, CA.

This season, the Yankees are 81-61 against the spread (ATS), while the Padres are 77-62 ATS.

Yankees vs Padres Starting Pitchers Today:

• Yankees starting pitcher: Gerrit Cole 8-7, 3.31 ERA
• Padres starting pitcher: Michael King 9-9, 3.11 ERA

Yankees vs. Padres Odds, Run Line, Over/Under & Moneyline

Yankees vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Sunday‘s MLB game with 54.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Yankees players for Sunday‘s game, looking at profitable historical betting trends:

Best Yankees Player Prop Bets Today:

• Spencer Jones has hit the Home Runs Over in 3 of his last 6 away games (+13.30 Units / 222% ROI)
• Spencer Jones has hit the Hits Runs and RBIs Over in 17 of his last 25 away games (+9.85 Units / 32% ROI)
• Cody Bellinger has hit the Runs Under in 16 of his last 20 away games (+9.30 Units / 28% ROI)
• Jazz Chisholm Jr. has hit the Singles Over in 12 of his last 20 games (+9.20 Units / 46% ROI)
• Spencer Jones has hit the Total Bases Over in 15 of his last 20 games (+9.15 Units / 34% ROI)

And here are some favorite MLB player prop bets for Padres players for Sunday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

• Michael King has hit the Pitching Outs Over in 19 of his last 25 games (+12.00 Units / 39% ROI)
• Samad Taylor has hit the Singles Over in 18 of his last 25 games (+11.75 Units / 44% ROI)
• Manny Machado has hit the RBIs Under in 20 of his last 25 games (+10.40 Units / 20% ROI)
• Jake Cronenworth has hit the Runs Under in his last 10 games (+10.00 Units / 49% ROI)
• Ty France has hit the Hits Over in 20 of his last 25 games at home (+9.85 Units / 20% ROI)

Yankees Best Bets Today:

• The New York Yankees have covered the Run Line in 29 of their last 50 games (+12.55 Units / 21% ROI)
• The New York Yankees have hit the Game Total Under in 23 of their last 35 away games (+9.85 Units / 25% ROI)
• The New York Yankees have hit the 1st Five Innings (F5) Moneyline in 13 of their last 25 away games (+9.45 Units / 28% ROI)
• The New York Yankees have hit the Moneyline in 31 of their last 50 away games (+9.15 Units / 15% ROI)
• The New York Yankees have covered the 1st Five Innings (F5) Run Line in 12 of their last 17 away games (+7.05 Units / 35% ROI)

Padres Best Bets Today:

• The San Diego Padres have covered the Run Line in 27 of their last 45 games (+12.65 Units / 22% ROI)
• The San Diego Padres have hit the Moneyline in 24 of their last 35 games at home (+11.10 Units / 25% ROI)
• The San Diego Padres have hit the Game Total Under in 29 of their last 50 games at home (+8.25 Units / 15% ROI)
• The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in their last 7 games at home (+7.20 Units / 88% ROI)
• The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 21 of their last 35 games at home (+5.40 Units / 13% ROI)

Yankees Against the Spread (ATS) Record

Against the spread this season, the Yankees are 70-71 against the Run Line (+7.3 Units / 4.52% ROI).

• 81-61 when betting on the Moneyline for -4.95 Units / -2.4% ROI
• 61-77 when betting on the total runs Over for -24.15 Units / -15.4% ROI
• 77-61 when betting on the total runs Under for +10.2 Units / 6.55% ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 77-62 against the Run Line (+11.2 Units / 5.97% ROI).

• 74-68 when betting on the Moneyline for +0.2 Units / 0.12% ROI
• 62-76 when betting on the total runs Over for -21.6 Units / -13.78% ROI
• 76-62 when betting on the total runs Under for +8.2 Units / 5.26% ROI

Yankees Keys to the Game vs. the Padres

The Yankees are 46-6 (.885) when they’ve hit 2 or more home runs this season — best in MLB.

The Yankees are 44-30 (.595) on the road this season — best in MLB.

The Yankees are 51-6 (.895) when scoring 5 or more runs this season — best in MLB.

The Yankees are 81-61 (.570) this season — 5th best in MLB.

Padres Keys to the Game vs. the Yankees

The Padres are 57-2 (.966) when leading entering the 8th inning this season — 4th best in MLB.

The Padres are 23-20 (.535) vs the top 10 runs allowed teams this season Today, they face Yankees (first fewest runs allowed).

The Padres are 13-8 (.619) when tied entering the 7th inning this season — 5th best in MLB.

The Padres are 48-34 (.585) vs the top 10 runs allowed teams since the 2025 season Today, they face Yankees (first fewest runs allowed).

Yankees Hitting Stats & Trends

Yankees hitters have an OBP of just .228 (2,905 PA’s) with two-strikes this season — lowest in MLB.

Yankees hitters have struck out in 25% of their PA’s this season — 3rd highest in MLB.

The Yankees are batting just .222 against starting pitchers this season — lowest in MLB.

Yankees hitters are slugging just .180 on pitches out of the zone this season — lowest in MLB.

Padres Hitting Stats & Trends

Padres hitters are slugging just .365 at home this season — 3rd lowest in MLB.

Padres hitters have an OPS of just .678 (2,577 PA’s) at home this season — 3rd lowest in MLB.

Padres hitters have put just 33% of balls in play to the right side of the field this season — lowest in MLB.

The Padres have answered-back in 37% of innings after an opponent scores in late innings this season — highest in MLB.

Yankees Pitching Stats & Trends

Yankees pitchers have an ERA of 2.94 (653.0 IP) on the road this season — best in MLB.

Yankees pitchers have an ERA of 2.80 (394.2 IP) against division opponents this season — best in MLB.

Yankees pitchers have an ERA of 3.22 (1270.0 IP) this season — best in MLB.

Opponents are hitting just .224 against Yankees pitchers this season — 3rd best in MLB.

Padres Pitching Stats & Trends

Padres pitchers have allowed innings of 3+ runs in 4% of innings played this season — 2nd lowest in MLB.

Padres pitchers have allowed an exit velocity over 105 MPH 246 times this season — 3rd fewest in MLB.

Padres pitchers have allowed an exit velocity of 95 MPH or greater 1,223 times this season — 5th fewest in MLB.

The Padres have allowed 3.70 runs per game (263/71) at home this season — 3rd best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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