Duke vs. Arizona Prediction, Odds: March Madness

  • Duke is predicted to be a -9.5-point favorite against Arizona.
  • Duke has won 29 of its last 30 games, including each of its last 13.
  • One NCAA betting system predicts the Blue Devils will cover the spread.

Looking for a third straight ATS success to begin the tournament, Duke faces Arizona in the Sweet 16.ย 

The Blue Devils cruised as double-digit favorites against Baylor, covering the spread in an 89-66 win. With a win against the Wildcats on Thursday, Duke would capture a 14th straight win.ย 

Arizona advanced to the Sweet 16 thanks to an 87-83 win over Oregon in the round of 32. Now, theyโ€™ll look for a 19th win in their last 21 against non-conference opponents as heavy dogs.ย 

Bet on Duke vs. Arizona and other March Madness matchups with up-to-date college basketball odds.ย 

Duke vs. Arizona Odds, March Madness

  • Duke Moneyline: -550
  • Arizona Moneyline: +400
  • Game Spread: Duke -9.5 (-110), Arizona +9.5 (-110)
  • Game Over/Under: 153.5 Points (-115/-105)

Duke vs. Arizona Prediction

Based on one historically profitable NCAAB betting system, the Duke vs. Arizona prediction for Thursdayโ€™s game is the Duke Spread (-9.5, -110).ย 

Two statistical factors are driving this prediction on Duke: the Blue Devilsโ€™ conversion rate from the free-throw line and Arizonaโ€™s relatively strong three-point defense.ย 

Dating back to the 2006 NCAA Tournament, history tells bettors to back favorites or short underdogs in this situation.ย 

Over that timeframe, teams between -20 and +2 are 53-14-1 ATS, assuming two factors:

  • The teamโ€™s free throw percentage falls between 77.2% and 85%
  • The underdogโ€™s defensive three-point percentage falls between 28.5% and 35.7%

Betting these teams has proven especially fruitful in the Sweet 16 onward. Over that same timeframe, these teams are 14-2 ATS from the regional semifinal onward.ย 

Just in the Sweet 16, these teams are 6-1 ATS.ย 

Irrespective of tournament round, favorites fitting this designation cover at a higher rate when listed as a big number.ย 

Shrink the sample down to games where the favorite closed between -20 and -7: 10-2-1 ATS, including 9-0 ATS in the last nine fits.ย 

As a result, bettors should consider laying the points with the Blue Devils on Thursday.ย 

Duke vs. Arizona: NCAAB Public Betting

TeamBets% (ATS)Money% (ATS)Bets% (ML)Money% (ML)
Arizona39%31%64%19%
Duke61%69%36%81%

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About the Author Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.