Kentucky vs Iowa State Prediction, Odds & Best Bets Today – NCAAB, Mar. 22

(AP Photo)
New Player OfferBetting Promos
  • Iowa State is a -4.5 point favorite vs Kentucky
  • Total (Over/Under): 145.5 points
  • Kentucky / Iowa State TV channel: CBS

The Kentucky Wildcats visit Enterprise Center to take on the Iowa State Cyclones on Mar. 22. Tip off is scheduled for 2:45 pm.

Iowa State is the betting favorite in this game, with the spread sitting at -4.5 (-110).

The Kentucky vs. Iowa State Over/Under is 145.5 total points.

Bet now on Iowa State vs Kentucky & all college basketball games with BetMGM

Kentucky vs. Iowa State Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Kentucky+4.5 -110O 145.5 -110+170
Iowa State -4.5 -110U 145.5 -110-210

Kentucky vs Iowa State Prediction for Today:

The winning team model predicts Iowa State will win this March Madness college basketball game with 58.8% confidence, based on game simulations, player injuries, key player performances and recent matchups.

Kentucky vs Iowa State Spread Prediction:

Based on recent against-the-spread trends, the spread model predicts Iowa State will cover the spread with 55.3% confidence for today’s game.


Bet now on Iowa State vs Kentucky and all games with BetMGM


  • Kentucky has hit the Moneyline in 13 of their last 20 games (+6.70 Units / 15% ROI)
  • Kentucky have covered the Spread in 10 of their last 14 games (+5.60 Units / 36% ROI)
  • Kentucky has hit the Game Total Over in 9 of their last 14 games (+3.50 Units / 23% ROI)
  • Kentucky has hit the Team Total Over in 9 of their last 14 games (+3.35 Units / 21% ROI)
  • Kentucky has hit the 1H Game Total Over in 9 of their last 14 games (+3.25 Units / 20% ROI)
  • Iowa State have covered the Spread in 12 of their last 17 games (+6.50 Units / 35% ROI)
  • Iowa State has hit the Game Total Under in 16 of their last 25 games (+6.10 Units / 22% ROI)
  • Iowa State has hit the Team Total Under in 16 of their last 25 games (+5.75 Units / 20% ROI)
  • Iowa State has hit the 1H Moneyline in their last 4 games (+4.20 Units / 11% ROI)
  • Iowa State has hit the 1H Game Total Over in 6 of their last 8 games (+3.70 Units / 40% ROI)

Kentucky Basketball Against the Spread Record (ATS)

Kentucky has a 18-17 record against the spread this college basketball season (-0.7 Units / -1.82% ROI).

  • 21-13 when betting on the Moneyline for -1.45 Units / -0.11% ROI
  • 18-17 when betting the Over for -0.7 Units / -1.82% ROI
  • 17-18 when betting the Under for -2.8 Units / -7.27% ROI

Iowa State Basketball Against the Spread Record (ATS)

Iowa State has a 21-14 record against the spread this college basketball season (+5.6 Units / 14.6% ROI).

  • 24-7 when betting on the Moneyline for +9.35 Units / 0.86% ROI
  • 15-20 when betting the Over for -7 Units / -18.18% ROI
  • 20-15 when betting the Under for +3.5 Units / 9.09% ROI

Kentucky Offensive Stats & Trends:

Kentucky averaged 89.1 points per game (2,673 points/30 games) last season — tied for best among Power Conference teams; League Avg: 75.6

Kentucky averaged 89.1 points per game (2,673 points/30 games) last season — tied for best among Division 1 Teams; League Avg: 73.6

Kentucky shot 41% from three (299/739) last season — 2nd best among Division 1 Teams; League Avg: 34%

Kentucky shot 41% from three (299/739) last season — 2nd best among Power Conference teams; League Avg: 35%

Iowa State Offensive Stats & Trends:

Iowa State has an eFG% of 55% in the first half this season — best among Big 12 Teams; League Avg: 52%

Iowa St. shot 53% off the dribble (107/203) last season in conference play — best among Big 12 Teams; League Avg: 44%

Iowa St. averaged 28.7 points per game (516 points/18 games) in possessions with a paint touch last season in conference play — lowest among Big 12 Teams; League Avg: 36.2

Iowa St. averaged 0.92 points per shot (108 points/118 shots) on mid-range shots last season in conference play — best among Big 12 Teams; League Avg: 0.73

Kentucky Defensive Stats & Trends:

Kentucky has allowed opponents to shoot 43% (422/975) in the second half this season — 2nd best among SEC Teams; League Avg: 45%

Kentucky allowed 9.0 made three-pointers per game last season — tied for 14th highest among Division 1 Teams; League Avg: 7.3

Kentucky has allowed 80.2 points per game (5,858 points/73 games) since the start of the 2023-24 season — tied for 2nd highest among Power Conference defenses; League Avg: 76.9

Kentucky has allowed opponents to shoot 31% from three (554/1,789) since the start of the 2024-25 season — 12th best among Division 1 Teams; League Avg: 34%

Iowa State Defensive Stats & Trends:

Iowa State forced 17.2 turnovers per game (636 turnovers/37 games) last season — 2nd best among Division 1 Teams; League Avg: 11.8

Iowa State has forced 15.0 turnovers per game (1,201 turnovers/80 games) since the start of the 2023-24 season — best among Power Conference defenses; League Avg: 11.1

Iowa State forced 16.2 turnovers per game (422 turnovers/26 games) last season — best among Power Conference defenses; League Avg: 11.3

Iowa St. allowed opponents to shoot 70% off the dribble (56/80) on shots around the rim last season in conference play — highest among Big 12 Teams; League Avg: 57%


Bet now on Iowa State vs Kentucky and all games with BetMGM


More College Basketball Betting at

BetMGM is the best online sportsbook for college basketball betting through the regular season and postseason. From futures like college basketball national championship odds and Final Four odds to team betting like Kentucky basketball oddsArizona basketball odds, or Kansas basketball odds, thereโ€™s something for everyone.

The content provided in this blog is intended for entertainment purposes only. All views and opinions expressed are the authors and reflect their individual perspectives on sports, betting, and related topics. This content should not be considered professional betting advice or the official views of BetMGM LLC. Please gamble responsibly. If you or someone you know is experiencing issues related to gambling, seek help from a licensed health professional. This blog is not liable for any losses, damages, or consequences resulting from betting activities.

About the Author Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.