Louisville vs Duke Prediction, Odds & Best Bets Today – NCAAB, Jan. 26

Duke head coach Jon Scheyer watches from the sideline against North Carolina State during the first half of an NCAA college basketball game in Raleigh, N.C., Wednesday, Jan. 4, 2023.
(AP Photo/Karl B DeBlaker)
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  • Duke is a -7.5 point favorite vs Louisville
  • Total (Over/Under): 156.5 points
  • Louisville / Duke TV channel: ESPN

The Louisville Cardinals visit Cameron Indoor Stadium to take on the Duke Blue Devils on Jan. 26. Tip off is scheduled for 7:00 pm in Durham, NC.

Duke is the betting favorite in this game, with the spread sitting at -7.5 (-110).

The Louisville vs. Duke Over/Under is 156.5 total points.

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Louisville vs. Duke Odds, Spread, Over/Under

Louisville vs Duke Prediction for Today:

The winning team model predicts Duke will win this college basketball game with 69.7% confidence, based on game simulations, player injuries, key player performances and recent matchups.

Louisville vs Duke Spread Prediction:

Based on recent against-the-spread trends, the spread model predicts Duke will cover the spread with 61.2% confidence for today’s game.


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  • Louisville has hit the Moneyline in 25 of their last 33 games (+9.20 Units / 0% ROI)
  • Louisville have covered the 1H Spread in 21 of their last 34 games (+7.20 Units / 18% ROI)
  • Louisville has hit the Game Total Under in 20 of their last 34 games (+4.70 Units / 13% ROI)
  • Louisville has hit the 1H Game Total Under in 20 of their last 34 games (+3.65 Units / 9% ROI)
  • Louisville has hit the Team Total Under in 8 of their last 12 away games (+3.55 Units / 26% ROI)
  • Duke has hit the Moneyline in 36 of their last 38 games (+30.95 Units / 1% ROI)
  • Duke have covered the 1H Spread in 17 of their last 25 games at home (+7.75 Units / 27% ROI)
  • Duke have covered the Spread in 24 of their last 39 games (+7.50 Units / 17% ROI)
  • Duke has hit the 1H Game Total Over in 23 of their last 39 games (+5.60 Units / 12% ROI)
  • Duke has hit the Game Total Over in 14 of their last 25 games at home (+1.90 Units / 7% ROI)

Louisville Basketball Against the Spread Record (ATS)

Louisville has a 10-9 record against the spread this college basketball season (+0.15 Units / 0.72% ROI).

  • 13-5 when betting on the Moneyline for +4.15 Units / 0.22% ROI
  • 8-11 when betting the Over for -4.15 Units / -19.81% ROI
  • 11-8 when betting the Under for +2.2 Units / 10.55% ROI

Duke Basketball Against the Spread Record (ATS)

Duke has a 11-8 record against the spread this college basketball season (+2.2 Units / 10.53% ROI).

  • 18-0 when betting on the Moneyline for +18 Units / 0.47% ROI
  • 7-12 when betting the Over for -6.2 Units / -29.67% ROI
  • 12-7 when betting the Under for +4.3 Units / 20.57% ROI

Louisville Offensive Stats & Trends:

Louisville had an assist to turnover ratio of 0.7 (154 assists/ 231 TOs) in the first half last season — lowest among ACC Teams; League Avg: 1.2

Louisville averaged 5.0 assists per game (154 assists/31 games) in the first half last season — lowest among ACC Teams; League Avg: 6.8

Louisville has made 11.9 three-pointers per game this season — 2nd best among Power Conference teams; League Avg: 8.5

Louisville averaged 11.1 assists per game (343 assists/31 games) last season — tied for 4th lowest among Power Conference teams; League Avg: 14.4

Duke Offensive Stats & Trends:

Duke has an assist to turnover ratio of 1.7 (1,529 assists/ 921 TOs) since the start of the 2023-24 season — tied for 3rd best among Division 1 Teams; League Avg: 1.2

Duke has averaged 1.49 points per shot (3,968 points/2,659 shots) in the second half since the start of the 2023-24 season — best among ACC Teams; League Avg: 1.36

Duke has an assist to turnover ratio of 1.7 (1,529 assists/ 921 TOs) since the start of the 2023-24 season — best among ACC Teams; League Avg: 1.3

Duke has an assist to turnover ratio of 1.8 (521 assists/ 292 TOs) in the first half since the start of the 2024-25 season — best among ACC Teams; League Avg: 1.2

Louisville Defensive Stats & Trends:

Louisville allowed opponents to shoot 48% (450/927) in the first half last season — highest among ACC Teams; League Avg: 43%

Louisville allowed an average of 1.40 points per shot (1,958 points/1,397 shots) last season — 5th highest among Power Conference defenses; League Avg: 1.28

Louisville has allowed opponents to shoot 35% (207/587) in the first half this season — best among ACC Teams; League Avg: 41%

Louisville allowed opponents to shoot 37% from three (266/714) last season — highest among ACC Teams; League Avg: 34%

Duke Defensive Stats & Trends:

Duke has allowed an average of 1.11 points per shot (6,004 points/5,410 shots) since the start of the 2023-24 season — best among ACC Teams; League Avg: 1.22

Duke has allowed 63.3 points per game (1,139 points/18 games) on the road since the start of the 2024-25 season — best among ACC Teams; League Avg: 74.9

Duke has allowed 65.1 points per game (1,952 points/30 games) on the road since the start of the 2023-24 season — best among ACC Teams; League Avg: 74.8

Duke allowed an average of 1.07 points per shot (2,448 points/2,286 shots) last season — tied for best among Division 1 Teams; League Avg: 1.24


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.