Louisville vs Indiana Prediction, Odds & Best Bets Today – NCAAB, Nov. 27

Indiana head coach Mike Woodson directs his team during the second half of an NCAA college basketball game against Iowa, Thursday, Jan. 5, 2023, in Iowa City, Iowa.
(AP Photo/Charlie Neibergall)
  • Indiana is a -2.5 point favorite vs Louisville
  • Total (Over/Under): 153.5 points
  • Louisville / Indiana TV channel: ESPN

The Louisville Cardinals visit Imperial Arena at Atlantis Resort to take on the Indiana Hoosiers on Nov. 27. Tip off is scheduled for 12:00pm EST in .

Indiana is the betting favorite in this game, with the spread sitting at -2.5 (-110).

The Louisville vs. Indiana Over/Under is 153.5 total points.

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Louisville vs. Indiana Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Louisville+2.5 -110O 153.5 -110+125
Indiana -2.5 -110U 153.5 -110-150

Louisville vs Indiana Prediction for Today:

The winning team model predicts Louisville will win this college basketball game with 75.8% confidence, based on game simulations, player injuries, key player performances and recent matchups.

Louisville vs Indiana Spread Prediction:

Based on recent against-the-spread trends, the spread model predicts Indiana will cover the spread with 55.4% confidence for today’s game.


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  • Louisville has hit the Game Total Under in 17 of their last 30 games (+2.70 Units / 8% ROI)
  • Indiana has hit the Moneyline in 18 of their last 31 games (+9.50 Units / 5% ROI)
  • Indiana has hit the 1H Game Total Over in 19 of their last 31 games (+6.30 Units / 18% ROI)
  • Indiana has hit the Team Total Under in 18 of their last 31 games (+3.10 Units / 9% ROI)
  • Indiana have covered the Spread in 16 of their last 31 games (+1.65 Units / 5% ROI)

Louisville Basketball Against the Spread Record (ATS)

Louisville has a 2-2 record against the spread this college basketball season (-0.2 Units / -4.55% ROI).

  • 3-1 when betting on the Moneyline for +1.5 Units / 0.88% ROI
  • 1-3 when betting the Over for -2.2 Units / -51.16% ROI
  • 3-1 when betting the Under for +1.9 Units / 42.22% ROI

Indiana Basketball Against the Spread Record (ATS)

Indiana has a 2-2 record against the spread this college basketball season (-0.2 Units / -4.55% ROI).

  • 4-0 when betting on the Moneyline for +4 Units / 3.18% ROI
  • 1-3 when betting the Over for -2.3 Units / -52.27% ROI
  • 3-1 when betting the Under for +1.9 Units / 43.18% ROI

Louisville Offensive Stats & Trends:

Louisville averaged 5.0 assists per game (154 assists/31 games) in the first half last season — lowest among ACC Teams; League Avg: 6.8

Louisville had an assist to turnover ratio of 0.7 (154 assists/ 231 TOs) in the first half last season — lowest among ACC Teams; League Avg: 1.2

Louisville had an assist to turnover ratio of 0.9 (343 assists/ 398 TOs) last season — 2nd lowest among ACC Teams; League Avg: 1.3

Louisville made 5.5 three-pointers per game last season — tied for 16th lowest among Division 1 Teams; League Avg: 7.5

Indiana Offensive Stats & Trends:

Indiana made 5.0 three-pointers per game last season — lowest among Power Conference teams; League Avg: 7.7

Indiana made 5.0 three-pointers per game last season — 8th lowest among Division 1 Teams; League Avg: 7.5

Indiana shot 67% from the free throw line (441/660) last season — 16th lowest among Division 1 Teams; League Avg: 72%

Indiana shot 67% from the free throw line (441/660) last season — 2nd lowest among Big 10 Teams; League Avg: 72%

Louisville Defensive Stats & Trends:

Louisville allowed an average of 1.35 points per shot (2,463 points/1,827 shots) last season — tied for highest among Division 1 Teams; League Avg: 1.23

Louisville allowed opponents to shoot 48% (872/1,827) last season — 4th highest among Division 1 Teams; League Avg: 44%

Louisville allowed an average of 1.35 points per shot (2,463 points/1,827 shots) last season — highest among ACC Teams; League Avg: 1.22

Louisville allowed opponents to shoot 48% (450/927) in the first half last season — highest among ACC Teams; League Avg: 43%

Indiana Defensive Stats & Trends:

Indiana averaged 5.3 steals per game (165 steals/31 games) last season — tied for 34th lowest among Division 1 Teams; League Avg: 6.7

Indiana allowed 8.6 made three-pointers per game last season — tied for 30th highest among Division 1 Teams; League Avg: 7.3

Indiana averaged 5.3 steals per game (165 steals/31 games) last season — tied for 3rd lowest among Big 10 Teams; League Avg: 6.3

Indiana allowed opponents to shoot 35% from three (143/412) in the first half last season — 5th highest among Big 10 Teams; League Avg: 35%


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.