Northwestern vs USC Prediction, Odds & Best Bets Today – NCAAB, Jan. 21

Southern California head coach Eric Musselman during the second half of an exhibition NCAA college basketball game, Saturday, Oct. 26, 2024, in Palm Desert, Calif. (AP Photo/Ryan Sun)
(AP Photo/Ryan Sun)
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  • USC is a -7.5 point favorite vs Northwestern
  • Total (Over/Under): 151.5 points
  • Northwestern / USC TV channel: BTN

The Northwestern Wildcats visit Galen Center to take on the USC Trojans on Jan. 21. Tip off is scheduled for 11:00pm EST in Los Angeles, CA.

USC is the betting favorite in this game, with the spread sitting at -7.5 (-105).

The Northwestern vs. USC Over/Under is 151.5 total points.

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Northwestern vs. USC Odds, Spread, Over/Under

Northwestern vs USC Prediction for Today:

The winning team model predicts USC will win this college basketball game with 66.8% confidence, based on game simulations, player injuries, key player performances and recent matchups.

Northwestern vs USC Spread Prediction:

Based on recent against-the-spread trends, the spread model predicts USC will cover the spread with 54.8% confidence for today’s game.


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  • Northwestern has hit the Team Total Over in 11 of their last 14 away games (+7.45 Units / 46% ROI)
  • Northwestern has hit the 1H Moneyline in 19 of their last 33 games (+6.55 Units / 1% ROI)
  • Northwestern has hit the Game Total Over in 20 of their last 33 games (+5.50 Units / 15% ROI)
  • USC has hit the 1H Moneyline in 13 of their last 18 games at home (+8.20 Units / 4% ROI)
  • USC has hit the 1H Game Total Under in 21 of their last 34 games (+6.15 Units / 16% ROI)
  • USC has hit the Game Total Over in 20 of their last 34 games (+4.60 Units / 12% ROI)
  • USC has hit the Team Total Over in 20 of their last 34 games (+3.75 Units / 10% ROI)
  • USC have covered the Spread in 11 of their last 18 games at home (+3.30 Units / 17% ROI)

Northwestern Basketball Against the Spread Record (ATS)

Northwestern has a 6-12 record against the spread this college basketball season (-7.05 Units / -35.88% ROI).

  • 8-10 when betting on the Moneyline for -4.45 Units / -0.41% ROI
  • 10-8 when betting the Over for +1.2 Units / 6.06% ROI
  • 8-10 when betting the Under for -3 Units / -15.15% ROI

USC Basketball Against the Spread Record (ATS)

USC has a 9-8 record against the spread this college basketball season (+0.25 Units / 1.34% ROI).

  • 13-4 when betting on the Moneyline for +8.45 Units / 2.12% ROI
  • 9-8 when betting the Over for +0.2 Units / 1.07% ROI
  • 8-9 when betting the Under for -1.9 Units / -10.16% ROI

Northwestern Offensive Stats & Trends:

USC averaged 6.8 turnovers per game (88 turnovers/13 games) in the second half last season — highest among Pac 12 Teams; League Avg: 5.8

USC has a 47% free throw rate (501 free throw attempts/1,073 field goal attempts) this season — 3rd highest among Power Conference teams; League Avg: 37%

USC has 27.8 free throw attempts per game this season — tied for 3rd best among Power Conference teams; League Avg: 22.3

USC has averaged 14.2 turnovers per game (484 turnovers/34 games) on the road since the start of the 2023-24 season — highest among Big 10 Teams; League Avg: 11.6

USC Offensive Stats & Trends:

USC has allowed opponents to shoot 42% (461/1,105) this season — 33rd best among Division 1 Teams; League Avg: 44%

USC forced 13.2 turnovers per game (397 turnovers/30 games) last season — tied for 50th best among Division 1 Teams; League Avg: 11.8

USC allowed an average of 1.38 points per shot (535 points/388 shots) in the second half last season — highest among Pac 12 Teams; League Avg: 1.25

USC allowed opponents to shoot 36% from three (250/695) last season — tied for 18th highest among Division 1 Teams; League Avg: 34%

Northwestern Defensive Stats & Trends:

USC averaged 6.8 turnovers per game (88 turnovers/13 games) in the second half last season — highest among Pac 12 Teams; League Avg: 5.8

USC has a 47% free throw rate (501 free throw attempts/1,073 field goal attempts) this season — 3rd highest among Power Conference teams; League Avg: 37%

USC has 27.8 free throw attempts per game this season — tied for 3rd best among Power Conference teams; League Avg: 22.3

USC has averaged 14.2 turnovers per game (484 turnovers/34 games) on the road since the start of the 2023-24 season — highest among Big 10 Teams; League Avg: 11.6

USC Defensive Stats & Trends:

USC has allowed opponents to shoot 42% (461/1,105) this season — 33rd best among Division 1 Teams; League Avg: 44%

USC forced 13.2 turnovers per game (397 turnovers/30 games) last season — tied for 50th best among Division 1 Teams; League Avg: 11.8

USC allowed an average of 1.38 points per shot (535 points/388 shots) in the second half last season — highest among Pac 12 Teams; League Avg: 1.25

USC allowed opponents to shoot 36% from three (250/695) last season — tied for 18th highest among Division 1 Teams; League Avg: 34%


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.