Cardinals vs Bengals Prediction, Odds & Best Prop Bets – NFL, Week 17

BetMGM Betting Dec 27, 2025, 11:11 AM

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A Cincinnati Bengals helmet sits on the turf prior to an NFL Football game against the Carolina Panthers, Sunday, Sep. 29, 2024, in Charlotte, N.C. (AP Photo/Brian Westerholt)

(AP Photo/Brian Westerholt)

The Bengals are -7 point favorites vs the Cardinals
Total (Over/Under): 53.5 points
Watch this game on FOX

The Arizona Cardinals (3-12-0) visit Paycor Stadium to take on the Cincinnati Bengals (5-10-0) on Dec. 28. Kickoff is scheduled for 1:00pm EST in Cincinnati, OH.

The Bengals are betting favorites in this matchup, with the spread sitting at -7 (-115).

The Cardinals vs. Bengals Over/Under is 53.5 total points for the game.

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Cardinals vs. Bengals Odds, Spread, Over/Under

Cardinals vs. Bengals Prediction

The winning team model predicts the Bengals will win this game with 74.5% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Cardinals vs Bengals Spread Prediction

Based on recent against-the-spread trends, the model predicts the Cardinals will cover the spread with 54.9% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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We’ve highlighted some favorite NFL player prop bets for Cardinals players this game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today

Jacoby Brissett has hit the TD Passes Over in 8 of his last 10 games (+8.35 Units / 74% ROI)
Jacoby Brissett has hit the Passing Yards Over in 9 of his last 10 games (+7.85 Units / 68% ROI)
Elijah Higgins has hit the Receptions Over in 6 of his last 8 games (+5.95 Units / 68% ROI)
Jacoby Brissett has hit the Pass Attempts Over in 8 of his last 10 games (+5.65 Units / 48% ROI)
Michael Carter has hit the Longest Reception Over in 6 of his last 7 games (+4.90 Units / 62% ROI)

And here are some top NFL player prop bets for Bengals players for this matchup, looking at profitable historical betting trends:

Best Bengals Player Prop Best Bets Today

Noah Fant has hit the Receiving Yards Over in 11 of his last 13 games (+8.70 Units / 58% ROI)
Ja’Marr Chase has hit the Receiving Yards Over in his last 7 games at home (+7.00 Units / 86% ROI)
Tee Higgins has hit the Longest Reception Over in 7 of his last 8 games (+5.85 Units / 63% ROI)
Samaje Perine has hit the Receptions Under in 6 of his last 7 games at home (+5.00 Units / 47% ROI)
Samaje Perine has hit the Receiving Yards Under in 6 of his last 7 games at home (+4.85 Units / 60% ROI)

Receiving Props: Total Receiving Yards for Bengals vs Cardinals

Player Name	Over	Under
Michael Carter (ARI)	17.5 -115	17.5 -115
Chase Brown (CIN)	22.5 -118	22.5 -110
Michael Wilson (ARI)	58.5 -118	58.5 -110
Tee Higgins (CIN)	54.5 -115	54.5 -115
Trey Mcbride (ARI)	68.5 -118	68.5 -115

Rushing Props: Total Rushing Yards for Bengals vs Cardinals

Player Name	Over	Under
Michael Carter (ARI)	48.5 -110	48.5 -118
Samaje Perine (CIN)	39.5 -115	39.5 -115
Chase Brown (CIN)	54.5 -115	54.5 -115
Joe Burrow (CIN)	4.5 -115	4.5 -115
Jacoby Brissett (ARI)	7.5 -110	7.5 -120

Cardinals Best Bets:

The Arizona Cardinals have covered the 3Q Spread in their last 8 away games (+8.00 Units / 80% ROI)
The Arizona Cardinals have hit the 3Q Moneyline in 6 of their last 8 away games (+7.70 Units / 87% ROI)
The Arizona Cardinals have hit the 4Q Game Total Over in 12 of their last 17 games (+6.35 Units / 33% ROI)
The Arizona Cardinals have covered the 2H Spread in 7 of their last 8 away games (+6.00 Units / 63% ROI)
The Arizona Cardinals have hit the 2H Moneyline in 4 of their last 8 away games (+4.70 Units / 52% ROI)

Bengals Best Bets:

The Cincinnati Bengals have hit the 2H Game Total Over in 10 of their last 14 games (+6.50 Units / 40% ROI)
The Cincinnati Bengals have hit the Game Total Over in 13 of their last 20 games (+5.30 Units / 24% ROI)
The Cincinnati Bengals have hit the 1H Game Total Over in 12 of their last 19 games (+3.95 Units / 18% ROI)
The Cincinnati Bengals have hit the 3Q Game Total Over in 5 of their last 8 games at home (+2.80 Units / 29% ROI)
The Cincinnati Bengals have hit the Team Total Over in 12 of their last 20 games (+2.60 Units / 11% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this NFL season, the Cardinals are 6-9 (-3.9 Units / -23.64% ROI).

Cardinals are 3-12 when betting on the Moneyline for -11.7 Units / -52.82% ROI
Cardinals are 9-6 when betting the Over for +2.4 Units / 14.55% ROI
Cardinals are 6-9 when betting the Under for -3.9 Units / ROI

Bengals Against the Spread (ATS) Record

Against the spread this NFL season, the Bengals are 7-8 (-1.8 Units / -10.91% ROI).

Bengals are 5-10 when betting on the Moneyline for -3.25 Units / -16.62% ROI
Bengals are 9-6 when betting the Over for +2.4 Units / 14.55% ROI
Bengals are 6-9 when betting the Under for -3.9 Units / -23.64% ROI

Arizona Cardinals: Keys to the Game vs. the Cincinnati Bengals

The Bengals defense has allowed an average of 21.9 fantasy points per game to TEs this season — worst in NFL; League Avg: 13.3.

The Bengals defense have missed 147 tackles this season — most in NFL.

Offenses facing the Bengals targeted WRs 46% of the time (216 Pass Attempts/475 plays) this season — lowest in NFL; League Avg: 55%.

The Bengals defense have allowed 7.1 yards per play in the 2nd half this season — worst in NFL; League Avg: 5.7.

Cincinnati Bengals: Keys to the Game vs. the Arizona Cardinals

The Cardinals have run the ball on 16% of plays (4 carries/25 plays) in the red zone since Week 13 — lowest in NFL; League Avg: 48%.

The Cardinals have gone three and out on 6% of their drives in the 1st quarter this season — 2nd-best in NFL; League Avg: 20%.

The Cardinals have run the ball on 35% of plays (335 carries/967 plays) this season — 2nd-lowest in NFL; League Avg: 42%.

Eight of the Cardinals offense’s 8 (100%) TDs have come through the air since Week 13 — highest in NFL; League Avg: 59%.

Additional Matchup Notes for Arizona Cardinals vs. Cincinnati Bengals