Cardinals vs Seahawks Prediction, Odds & Best Prop Bets โ€“ NFL, Week 12

(AP Photo/Abbie Parr)
  • The Cardinals are -1 point favorites vs the Seahawks
  • Total (Over/Under): 47.5 points
  • Watch this game on FOX

The Arizona Cardinals (6-4-0) visit Lumen Field to take on the Seattle Seahawks (5-5-0) on Nov. 24. Kickoff is scheduled for 4:25pm EST in Seattle, WA.

The Cardinals are betting favorites in this matchup, with the spread sitting at -1 (-105).

The Cardinals vs. Seahawks Over/Under is 47.5 total points for the game.

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Cardinals vs. Seahawks Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Cardinals-1 -10547.5 -110-110
Seahawks +1 -11547.5 -110-110

Cardinals vs. Seahawks Prediction

The winning team model predicts the Cardinals will win this game with 53.0% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Cardinals vs Seahawks Spread Prediction

Based on recent against-the-spread trends, the model predicts the Cardinals will cover the spread with 60.0% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for Cardinals players this playoff game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today

  • Marvin Harrison Jr. has hit the Receptions Under in 8 of his last 10 games (+6.15 Units / 51% ROI)
  • Kyler Murray has hit the Interceptions Under in 11 of his last 16 games (+5.65 Units / 29% ROI)
  • Kyler Murray has hit the Carries Under in 11 of his last 16 games (+5.55 Units / 28% ROI)
  • James Conner has hit the Longest Rush Over in his last 5 games (+5.00 Units / 85% ROI)
  • James Conner has hit the Carries Over in 11 of his last 16 games (+5.00 Units / 27% ROI)

And here are some top NFL player prop bets for Seahawks players for this matchup, looking at profitable historical betting trends:

Best Seahawks Player Prop Best Bets Today

  • Geno Smith has hit the Carries Over in 9 of his last 11 games (+7.65 Units / 56% ROI)
  • Noah Fant has hit the Receptions Over in 10 of his last 13 games (+7.10 Units / 42% ROI)
  • Sam Howell has hit the Interceptions Over in his last 6 games (+6.00 Units / 59% ROI)
  • Zach Charbonnet has hit the Rushing Yards Under in 12 of his last 17 games (+5.80 Units / 28% ROI)
  • Geno Smith has hit the TD Passes Under in 7 of his last 8 games at home (+5.70 Units / 50% ROI)
  • The Arizona Cardinals have hit the 4Q Moneyline in 10 of their last 16 games (+8.10 Units / 48% ROI)
  • The Arizona Cardinals have covered the 4Q Spread in 12 of their last 16 games (+7.50 Units / 40% ROI)
  • The Arizona Cardinals have hit the Moneyline in 4 of their last 9 away games (+6.70 Units / 71% ROI)
  • The Arizona Cardinals have hit the 2H Moneyline in 8 of their last 12 games (+6.10 Units / 48% ROI)
  • The Arizona Cardinals have covered the 2H Spread in 9 of their last 13 games (+5.08 Units / 34% ROI)
  • The Seattle Seahawks have hit the 3Q Game Total Over in 13 of their last 17 games (+8.55 Units / 43% ROI)
  • The Seattle Seahawks have hit the 4Q Game Total Over in 11 of their last 17 games (+5.15 Units / 26% ROI)
  • The Seattle Seahawks have hit the 2Q Game Total Over in 10 of their last 17 games (+3.15 Units / 16% ROI)
  • The Seattle Seahawks have scored last in 4 of their last 5 games (+3.00 Units / 51% ROI)
  • The Seattle Seahawks have hit the 2H Game Total Over in 5 of their last 7 games at home (+2.72 Units / 36% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this NFL season, the Cardinals art 7-3 (+3.6 Units / 32.14% ROI).

  • Cardinals are 6-4 when betting on the Moneyline for +4.1 Units / 36.77% ROI
  • Cardinals are 4-5 when betting the Over for -1.5 Units / -13.64% ROI
  • Cardinals are 5-4 when betting the Under for +0.6 Units / ROI

Seahawks Against the Spread (ATS) Record

Against the spread this NFL season, the Seahawks are 3-6 (-3.6 Units / -32.73% ROI).

  • Seahawks are 5-5 when betting on the Moneyline for -0.5 Units / -3.23% ROI
  • Seahawks are 5-5 when betting the Over for -0.5 Units / -4.55% ROI
  • Seahawks are 5-5 when betting the Under for -0.5 Units / -4.55% ROI

Arizona Cardinals: Keys to the Game vs. the Seattle Seahawks

The Cardinals were winless (0-3) when forcing 2 or more turnovers last season — worst in NFL; League Avg: .707.

The Cardinals were 1-6 (.143) when sacking the QB 3 or more times last season — 2nd-worst in NFL; League Avg: .650.

The Cardinals were winless (0-10) when scoring less than 22 points last season — T-worst in NFL; League Avg: .253.

The Cardinals were winless (0-5) when allowing 250 or more passing yards last season — T-worst in NFL; League Avg: .414.

Seattle Seahawks: Keys to the Game vs. the Arizona Cardinals

The Seahawks are 5-1 (.833) when rushing for 120 or more yards since the 2023 season — T-best in NFL. The Cardinals have allowed an average of 138.0 rushing yards per game since the 2023 season — 4th-worst in NFL.

The Seahawks are winless (0-4) when allowing 5 or more explosive passes this season — T-worst in NFL; League Avg: .410.

The Seahawks were 3-7 (.300) when committing 1 or more turnovers last season — 8th-worst in NFL; League Avg: .406.

The Seahawks were 4-3 (.571) when not forcing a turnover last season — 7th-best in NFL; League Avg: .265.

Additional Matchup Notes for Arizona Cardinals vs. Seattle Seahawks

The Seahawks have run successful plays on just 37.5% of pass attempts against a heavy rush since the 2023 season — 4th-worst in NFL. The Cardinals have allowed successful plays on just 25.0% of pass attempts with a heavy rush since the 2023 season — best in NFL.

The Seahawks have been successful on 57.1% of plays they have ran against a light rush since the 2023 season — best in NFL. The Cardinals have allowed their opponents to be successful on 53.3% of plays with a light rush since the 2023 season — 3rd-worst in NFL.

The Seahawks have run successful plays on 52.9% of pass attempts against a base rush this season — 4th-best in NFL. The Cardinals have allowed successful plays on 49.4% of pass attempts with a base rush this season — 4th-worst in NFL.

The Cardinals have averaged 0.17 epa per play against a stacked front since the 2023 season — T-3rd-best in NFL. The Seahawks have allowed 0.18 epa per play with a stacked front since the 2023 season — 3rd-worst in NFL.

Cardinals RBs have averaged 2.4 yards after contact per carry since the 2023 season — best in NFL. The Seahawks have allowed 2.1 yards after contact per carry since the 2023 season — T-2nd-worst in NFL.

Cardinals RBs have averaged 10.8 yards after the catch this season — 3rd-best in NFL. The Seahawks have allowed 9.5 yards after catch per reception to RBs this season — T-4th-worst in NFL.

Arizona Cardinals Offense: Important Stats

The Cardinals had 23 rushes of 20+ yards last season — most in NFL.

The Cardinals have run the ball on 39% of plays (40 carries/104 plays) on 3rd down this season — highest in NFL; League Avg: 25%.

The Cardinals have run successful plays on 80% of pass attempts against a light front since Week 8 — best in NFL; League Avg: 42%.

The Cardinals have targeted TEs 31% of the time (261 Pass Attempts/831 plays) since the 2023 season — highest in NFL; League Avg: 21%.

Seattle Seahawks Offense: Important Stats

The Seahawks have averaged -1.95 epa per play on contested throws since Week 8 — worst in NFL; League Avg: -0.02.

The Seahawks averaged 0.63 epa per play against a light rush last season — best in NFL; League Avg: -0.04.

The Seahawks ran successful plays on 68% of plays against a light rush last season — best in NFL; League Avg: 39%.

The Seahawks have averaged -0.46 epa per play on motion plays since Week 8 — worst in NFL; League Avg: 0.02.

Arizona Cardinals Defense: Important Stats

19% of the plays ran against the Cardinals were in the red zone last season — worst in NFL; League Avg: 14%.

The Cardinals defense has allowed a third down conversion rate of 35% on third and 10+ yards to go this season — worst in NFL; League Avg: 17%.

The Cardinals defense has allowed a passer rating of just 0.0 with a stacked front (0 Pass Attempts) this season — best in NFL; League Avg: 109.9.

The Cardinals defense has allowed successful plays on 55% of pass attempts from their own territory since the 2023 season — worst in NFL; League Avg: 47%.

Seattle Seahawks Defense: Important Stats

The Seahawks defense forced three and outs on 2% of opponent drives in the 4th quarter last season — worst in NFL; League Avg: 17%.

The Seahawks defense forced three and outs on 7% of opponent drives in the 2nd half last season — worst in NFL; League Avg: 20%.

The Seahawks defense allowed 3 TD passes in close and late situations last season — T-most in NFL.

The Seahawks defense have forced three and outs on 30% of opponent drives this season — best in NFL; League Avg: 21%.

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About the Author

Nick Hennion

Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.