- The Chargers (8-6) are -4 point favorites vs the Colts (4-9)
- Total (Over/Under): 47 points
- Watch the game on ESPN
The Los Angeles Chargers (8-6) visit Lucas Oil Stadium to take on the Indianapolis Colts (4-9) on Dec. 26. Kickoff is scheduled for 8:15pm EST in Indianapolis for Monday Night Football.
The Chargers are betting favorites in Week 16, with the spread sitting at -4.5 (-110).
The Chargers vs. Colts Over/Under is 45.5 total points for the game.
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Chargers vs. Colts Odds, Spread, Over/Under Week 16
| Spread | Total (O/U) | Moneyline | |
| Chargers | -4.5 -110 | 45.5 -110 | -210 |
| Colts | +4.5 -110 | 45.5 -110 | +170 |
Chargers vs. Colts Prediction for Week 16
Based on recent trends, the winning team model predicts the Chargers will win this Week 16 game with 69.3% confidence.
Chargers vs Colts Spread Prediction for Week 16
Based on recent against-the-spread trends, the model predicts the Chargers will cover the spread this Week 16 with 62.0% confidence.
Both predictions factor in up-to-date player injuries for both the Chargers and Colts, plus offensive & defensive matchups, recent games and key player performances this season.
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Best Chargers Player Prop Bets Today
We’ve highlighted some favorite NFL player prop bets for Chargers players for Week 16, looking at profitable historical betting trends:
- Justin Herbert has hit the Completions Over in 12 of his last 16 games (+7.70 Units / 44% ROI)
- Gerald Everett has hit the Receptions Over in 11 of his last 15 games (+6.80 Units / 40% ROI)
- Austin Ekeler has hit the Receiving Yards Over in 11 of his last 16 games (+5.35 Units / 29% ROI)
- Justin Herbert has hit the Pass Attempts Over in 11 of his last 16 games (+5.25 Units / 29% ROI)
- Austin Ekeler has hit the Receptions Over in 10 of his last 15 games (+5.20 Units / 29% ROI)
Best Colts Player Prop Best Bets Today
And here are some top NFL player prop bets for Colts players for Week 16, looking at profitable historical betting trends:
- Michael Pittman has hit the Receptions Over in 12 of his last 16 games (+7.95 Units / 43% ROI)
- Jonathan Taylor has hit the Rushing Yards Under in his last 6 games at home (+6.00 Units / 76% ROI)
- Parris Campbell has hit the Receiving Yards Over in 8 of his last 11 games (+4.75 Units / 39% ROI)
- Alec Pierce has hit the Receptions Under in 7 of his last 9 games (+4.60 Units / 33% ROI)
- Jonathan Taylor has hit the Receiving Yards Under in 5 of his last 6 games at home (+3.80 Units / 50% ROI)
First Touchdown Scorer Bet for Colts vs Chargers
| Player Name | 1st TD Odds |
|---|---|
| Austin Ekeler | +400 |
| Keenan Allen | +750 |
| Zack Moss | +800 |
| Mike Williams | +800 |
| Deon Jackson | +900 |
Anytime Touchdown Scorer Bet for Colts vs Chargers
| Player Name | Anytime TD Odds |
|---|---|
| Austin Ekeler | -200 |
| Zack Moss | -115 |
| Deon Jackson | +100 |
| Keenan Allen | +120 |
| Mike Williams | +125 |
Receiving Props: Total Receiving Yards for Colts vs Chargers
| Player Name | Over | Under |
|---|---|---|
| Michael Pittman Jr. | 65.5 -115 | 65.5 -115 |
| Alec Pierce | 40.5 -115 | 40.5 -115 |
| Parris Campbell | 36.5 -120 | 36.5 -110 |
Chargers Best Bets for Week 16:
- The Los Angeles Chargers have covered the 2Q Spread in 13 of their last 16 games (+9.35 Units / 52% ROI)
- The Los Angeles Chargers have hit the 2H Game Total Under in 9 of their last 10 games (+9.05 Units / 83% ROI)
- The Los Angeles Chargers have hit the 2Q Moneyline in 12 of their last 16 games (+8.75 Units / 39% ROI)
- The Los Angeles Chargers have hit the Team Total Under in 11 of their last 14 games (+7.90 Units / 50% ROI)
- The Los Angeles Chargers have hit the 2Q Game Total Over in 9 of their last 12 games (+6.65 Units / 47% ROI)
Colts Best Bets for Week 16:
- The Indianapolis Colts have hit the Team Total Under in 13 of their last 17 games (+8.30 Units / 43% ROI)
- The Indianapolis Colts have hit the 1H Game Total Under in 12 of their last 17 games (+7.55 Units / 40% ROI)
- The Indianapolis Colts have hit the 1Q Game Total Under in 12 of their last 16 games (+7.25 Units / 37% ROI)
- The Indianapolis Colts have hit the Game Total Under in 12 of their last 17 games (+6.50 Units / 35% ROI)
- The Indianapolis Colts have covered the 3Q Spread in 9 of their last 12 games (+6.05 Units / 41% ROI)
Chargers Against the Spread (ATS) Record
Against the spread this NFL season, the Chargers have gone 8-5 (+2.5 Units / 16.39% ROI).
- Chargers are 8-6 when betting on the Moneyline for -0.45 Units / -2.07% ROI
- Chargers are 5-8 when betting the Over for -3.8 Units / -24.68% ROI
- Chargers are 8-5 when betting the Under for +2.5 Units / ROI
Colts Against the Spread (ATS) Record
Against the spread this NFL season, the Colts have gone 6-8 (-2.65 Units / -17.49% ROI).
- Colts are 4-9 when betting on the Moneyline for -5.35 Units / -27.94% ROI
- Colts are 5-9 when betting the Over for -4.9 Units / -31.82% ROI
- Colts are 9-5 when betting the Under for +3.5 Units / 22.73% ROI
Los Angeles Chargers: Keys to the Game vs. the Indianapolis Colts
The Chargers are 5-1 (.833) when allowing less than 3 explosive runs this season — 5th-best in NFL; League Avg: .568.
The Chargers are undefeated (5-0) when allowing less than 22 points this season — tied for best in NFL; League Avg: .712.
The Chargers are 7-2 (.778) when favorites this season — tied for 8th-best in NFL; League Avg: .643.
The Chargers are 5-3 (.625) when within 7 points entering the 4th quarter this season — tied for 9th-best in NFL; League Avg: .496.
Indianapolis Colts: Keys to the Game vs. the Los Angeles Chargers
The Colts are 1-4-1 (.167) when favorites this season — 3rd-worst in NFL; League Avg: .643.
The Colts are 3-9-1 (.231) when averaging less than 5 yards per rush this season — 4th-worst in NFL; League Avg: .471.
The Colts are 2-9 (.182) when making less than 3 explosive runs in a game this season — 5th-worst in NFL; League Avg: .429.
The Colts are 2-5 (.286) when not forcing a fumble this season — tied for 9th-worst in NFL; League Avg: .432.
Additional Matchup Notes for Los Angeles Chargers vs. Indianapolis Colts
The Colts have a third down conversion rate of just 9.1% in the fourth quarter since Week 12 — second-worst in NFL. The Chargers defense has allowed a third down conversion rate of just 21.4% in the 4th quarter since Week 12 — fifth-best in NFL.
Colts WRs averaged just 2.2 yards after the catch last week — fifth-worst in NFL. The Chargers allowed just 1.8 yards after catch per reception to WRs in Week 14 — best in NFL.
Chargers WRs have been targeted 104 times since Week 12 — fourth-most in NFL. The Colts have allowed an average of 31.1 fantasy points per game to WRs since Week 12 — second-worst in NFL.
Chargers WRs have averaged 26.0 targets per game since Week 12 — fourth-highest in NFL. The Colts have allowed 15.7 receptions per game to WRs since Week 12 — fourth-worst in NFL.
Chargers WRs have 73 receptions in 4 games (18.2 per game) since Week 12 — second-best in NFL. The Colts have allowed 15.7 receptions per game to WRs since Week 12 — fourth-worst in NFL.
Los Angeles Chargers Offense: Important Stats for Week 16
The Chargers averaged 121.6 yards from scrimmage per game (2,067 yards / 17 games) in the 4th quarter last season — best in NFL; League Avg: 94.8.
The Chargers have not recorded a TD in 12 drives in the 3rd quarter since Week 12 of the 2021 Season — tied for worst Drives Per TD rate in NFL; League Avg: 5.3.
The Chargers faced a blitz 26 times in Week 14 — most in NFL.
The Chargers had a third down conversion rate of 35% on third and 10+ yards to go last season — best in NFL; League Avg: 20%.
Indianapolis Colts Offense: Important Stats for Week 16
The Colts are averaging 11.7 drives per TD in the 1st half this season — worst Drives Per TD rate in NFL; League Avg: 4.7.
The Colts averaged 16.0 drives per TD in Week 15 — 2nd-worst Drives Per TD rate in NFL; League Avg: 4.8.
The Colts have not recorded a TD in 13 drives in the 4th quarter since Week 12 of the 2021 Season — tied for worst Drives Per TD rate in NFL; League Avg: 5.0.
The Colts have run 32% of their plays in the red zone in the 1st quarter since Week 12 of the 2021 Season — best in NFL; League Avg: 10%.
Los Angeles Chargers Defense: Important Stats for Week 16
The Chargers defense has allowed an average of 2.2 yards after contact per carry (871 carries) since the 2021 season — worst in NFL; League Avg: 1.8.
The Chargers defense has allowed successful plays on 61% of rush attempts in the 3rd quarter this season — worst in NFL; League Avg: 46%.
The Chargers defense has stuffed 35% (9/26) of rushing attempts on 3rd and short this season — 2nd-best in NFL; League Avg: 22%.
The Chargers defense allowed a third down conversion rate of 57% in the 2nd half last season — worst in NFL; League Avg: 40%.
Indianapolis Colts Defense: Important Stats for Week 16
The Colts defense has allowed successful plays on 33% of rush attempts in the 4th quarter this season — best in NFL; League Avg: 43%.
The Colts defense allowed a passer rating of just 47.5 on 3rd and short (36 Pass Attempts) last season — best in NFL; League Avg: 98.4.
The Colts defense has allowed 23.7 points per game to opposing offenses (71 points / 3 games) in the 2nd half since Week 12 of the 2021 Season — worst in NFL; League Avg: 10.3.
The Colts defense has allowed an average of 32.2 fantasy points per game as a unit to RBs since Week 12 of the 2021 Season — 2nd-worst in NFL; League Avg: 17.9.
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