Cowboys vs Panthers Prediction, Odds & Best Prop Bets โ€“ NFL, Week 6

Fans stand for the national anthem before an NFL football game between the Carolina Panthers and the New Orleans Saints Monday, Sept. 18, 2023, in Charlotte, N.C. (AP Photo/Rusty Jones)
(AP Photo/Rusty Jones)
  • The Cowboys are -3 point favorites vs the Panthers
  • Total (Over/Under): 49.5 points
  • Watch this game on FOX

The Dallas Cowboys (2-2-1) visit Bank of America Stadium to take on the Carolina Panthers (2-3-0) on Oct. 12. Kickoff is scheduled for 1:00pm EDT in Charlotte, NC.

The Cowboys are betting favorites in this matchup, with the spread sitting at -3 (-110).

The Cowboys vs. Panthers Over/Under is 49.5 total points for the game.

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Cowboys vs. Panthers Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Cowboys-3 -11049.5 -110-170
Panthers +3 -11049.5 -110140

Cowboys vs. Panthers Prediction

The winning team model predicts the Cowboys will win this game with 62.4% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Cowboys vs Panthers Spread Prediction

Based on recent against-the-spread trends, the model predicts the Cowboys will cover the spread with 50.5% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for Cowboys players this game, looking at profitable historical betting trends:

Best Cowboys Player Prop Bets Today

  • CeeDee Lamb has hit the Receptions Over in 10 of his last 13 games (+6.50 Units / 40% ROI)
  • Jake Ferguson has hit the Receiving Yards Under in 11 of his last 15 games (+6.40 Units / 38% ROI)
  • Javonte Williams has hit the Receptions Under in 7 of his last 10 away games (+5.10 Units / 45% ROI)
  • Javonte Williams has hit the Longest Rush Over in his last 5 games (+5.05 Units / 89% ROI)
  • Dak Prescott has hit the Passing Yards Under in his last 5 away games (+5.00 Units / 87% ROI)

And here are some top NFL player prop bets for Panthers players for this matchup, looking at profitable historical betting trends:

Best Panthers Player Prop Best Bets Today

  • Bryce Young has hit the TD Passes Over in 10 of his last 15 games (+7.60 Units / 41% ROI)
  • Bryce Young has hit the Completions Under in 10 of his last 14 games (+5.90 Units / 38% ROI)
  • Rico Dowdle has hit the Rushing Yards Over in 11 of his last 16 games (+5.25 Units / 28% ROI)
  • Rico Dowdle has hit the Carries Over in 9 of his last 13 games (+4.30 Units / 28% ROI)
  • Bryce Young has hit the Pass Attempts Under in 6 of his last 8 games at home (+3.85 Units / 43% ROI)

Receiving Props: Total Receiving Yards for Panthers vs Cowboys

Player Name Over Under
Luke Schoonmaker (DAL) 5.5 -110 5.5 -120
Javonte Williams (DAL) 18.5 -110 18.5 -118
Jake Ferguson (DAL) 44.5 -110 44.5 -118
Ryan Flournoy (DAL) 36.5 -135 36.5 +100
Tetairoa McMillan (CAR) 64.5 -115 64.5 -115

Rushing Props: Total Rushing Yards for Panthers vs Cowboys

Player Name Over Under
Bryce Young (CAR) 10.5 -115 10.5 -115
Javonte Williams (DAL) 66.5 -115 66.5 -115
  • The Dallas Cowboys have covered the 2Q Spread in 13 of their last 17 games (+8.45 Units / 44% ROI)
  • The Dallas Cowboys have hit the Game Total Over in 14 of their last 20 games (+7.40 Units / 34% ROI)
  • The Dallas Cowboys have hit the 2Q Moneyline in 9 of their last 17 games (+6.40 Units / 34% ROI)
  • The Dallas Cowboys have hit the 1H Game Total Over in 13 of their last 19 games (+6.00 Units / 27% ROI)
  • The Dallas Cowboys have hit the 3Q Game Total Over in 11 of their last 17 games (+4.30 Units / 22% ROI)
  • The Carolina Panthers have hit the 2Q Game Total Over in 13 of their last 17 games (+8.75 Units / 47% ROI)
  • The Carolina Panthers have hit the 1H Game Total Over in 12 of their last 19 games (+7.45 Units / 34% ROI)
  • The Carolina Panthers have hit the Game Total Over in 13 of their last 20 games (+5.30 Units / 24% ROI)
  • The Carolina Panthers have covered the 3Q Spread in 7 of their last 9 games at home (+4.90 Units / 45% ROI)
  • The Carolina Panthers have hit the 4Q Moneyline in 8 of their last 17 games (+4.53 Units / 26% ROI)

Cowboys Against the Spread (ATS) Record

Against the spread this NFL season, the Cowboys are 3-2 (+0.8 Units / 14.55% ROI).

  • Cowboys are 2-2 when betting on the Moneyline for -0.2 Units / -3.01% ROI
  • Cowboys are 3-2 when betting the Over for +0.8 Units / 14.55% ROI
  • Cowboys are 2-3 when betting the Under for -1.3 Units / ROI

Panthers Against the Spread (ATS) Record

Against the spread this NFL season, the Panthers are 3-2 (+0.8 Units / 14.55% ROI).

  • Panthers are 2-3 when betting on the Moneyline for -0.1 Units / -2% ROI
  • Panthers are 3-2 when betting the Over for +0.8 Units / 14.55% ROI
  • Panthers are 2-3 when betting the Under for -1.3 Units / -23.64% ROI

Dallas Cowboys: Keys to the Game vs. the Carolina Panthers

The Panthers have averaged -0.16 epa per play on play action passes since the 2024 season — 3rd-worst in NFL; League Avg: 0.09.

The Panthers go for it on fourth down 37% of the time this season — highest in NFL; League Avg: 21%.

The Panthers have averaged just 1.4 yards per play against tight coverage this season — 2nd-worst in NFL; League Avg: 3.1.

The Panthers have averaged just 8.0 yards per play against open coverage since the 2024 season — 2nd-worst in NFL; League Avg: 9.3.

Carolina Panthers: Keys to the Game vs. the Dallas Cowboys

The Cowboys have run the ball on 12% of plays (7 carries/60 plays) on 3rd down this season — lowest in NFL; League Avg: 26%.

The Cowboys have committed 12 turnovers in the red zone since the 2024 season — most in NFL.

The Cowboys have run the ball on 27% of plays (4 carries/15 plays) on 3rd and short this season — lowest in NFL; League Avg: 53%.

The Cowboys have thrown the ball 73% of the time (11 Pass Attempts/15 plays) on 3rd and short this season — highest in NFL; League Avg: 44%.

Additional Matchup Notes for Dallas Cowboys vs. Carolina Panthers

The Cowboys have run the ball on 12% of plays (7 carries/60 plays) on 3rd down this season — lowest in NFL; League Avg: 26%.

The Cowboys have committed 12 turnovers in the red zone since the 2024 season — most in NFL.

The Cowboys have run the ball on 27% of plays (4 carries/15 plays) on 3rd and short this season — lowest in NFL; League Avg: 53%.

The Cowboys have thrown the ball 73% of the time (11 Pass Attempts/15 plays) on 3rd and short this season — highest in NFL; League Avg: 44%.

The Panthers have averaged -0.16 epa per play on play action passes since the 2024 season — 3rd-worst in NFL; League Avg: 0.09.

The Panthers go for it on fourth down 37% of the time this season — highest in NFL; League Avg: 21%.

The Panthers have averaged just 1.4 yards per play against tight coverage this season — 2nd-worst in NFL; League Avg: 3.1.

The Panthers have averaged just 8.0 yards per play against open coverage since the 2024 season — 2nd-worst in NFL; League Avg: 9.3.

Dallas Cowboys Offense: Important Stats

The Panthers have averaged -0.16 epa per play on play action passes since the 2024 season — 3rd-worst in NFL; League Avg: 0.09.

The Panthers go for it on fourth down 37% of the time this season — highest in NFL; League Avg: 21%.

The Panthers have averaged just 1.4 yards per play against tight coverage this season — 2nd-worst in NFL; League Avg: 3.1.

The Panthers have averaged just 8.0 yards per play against open coverage since the 2024 season — 2nd-worst in NFL; League Avg: 9.3.

Carolina Panthers Offense: Important Stats

The Cowboys have run the ball on 12% of plays (7 carries/60 plays) on 3rd down this season — lowest in NFL; League Avg: 26%.

The Cowboys have committed 12 turnovers in the red zone since the 2024 season — most in NFL.

The Cowboys have run the ball on 27% of plays (4 carries/15 plays) on 3rd and short this season — lowest in NFL; League Avg: 53%.

The Cowboys have thrown the ball 73% of the time (11 Pass Attempts/15 plays) on 3rd and short this season — highest in NFL; League Avg: 44%.

Dallas Cowboys Defense: Important Stats

The Panthers have averaged -0.16 epa per play on play action passes since the 2024 season — 3rd-worst in NFL; League Avg: 0.09.

The Panthers go for it on fourth down 37% of the time this season — highest in NFL; League Avg: 21%.

The Panthers have averaged just 1.4 yards per play against tight coverage this season — 2nd-worst in NFL; League Avg: 3.1.

The Panthers have averaged just 8.0 yards per play against open coverage since the 2024 season — 2nd-worst in NFL; League Avg: 9.3.

Carolina Panthers Defense: Important Stats

The Cowboys have run the ball on 12% of plays (7 carries/60 plays) on 3rd down this season — lowest in NFL; League Avg: 26%.

The Cowboys have committed 12 turnovers in the red zone since the 2024 season — most in NFL.

The Cowboys have run the ball on 27% of plays (4 carries/15 plays) on 3rd and short this season — lowest in NFL; League Avg: 53%.

The Cowboys have thrown the ball 73% of the time (11 Pass Attempts/15 plays) on 3rd and short this season — highest in NFL; League Avg: 44%.

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.