Falcons vs 49ers Prediction, Odds & Best Prop Bets – NFL, Week 7

BetMGM Betting Oct 15, 2025, 6:49 PM

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An exterior of Levi's Stadium is shown before an NFL preseason football game between the San Francisco 49ers and the Los Angeles Chargers in Santa Clara, Calif., Thursday, Aug. 29, 2019. (AP Photo/Tony Avelar)

(AP Photo/Tony Avelar)

The Favorite Team are Favorite Spread point favorites vs the Underdog Team
Total (Over/Under): 47 points
Watch this game on NBC | PEAC | NBCU

The Atlanta Falcons (3-2-0) visit Levi's Stadium to take on the San Francisco 49ers (4-2-0) on Oct. 19. Kickoff is scheduled for 8:20pm EDT in Santa Clara, CA.

The are betting favorites in this matchup, with the spread sitting at ().

The Falcons vs. 49ers Over/Under is 47 total points for the game.

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Falcons vs. 49ers Odds, Spread, Over/Under

	Spread	Total (O/U)	Moneyline
Falcons	+2 -110	47 -110	110
49ers	+49 -110	47 -110	-135

Falcons vs. 49ers Prediction

The winning team model predicts the 49ers will win this game with 59.0% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Falcons vs 49ers Spread Prediction

Based on recent against-the-spread trends, the model predicts the Falcons will cover the spread with 53.8% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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We’ve highlighted some favorite NFL player prop bets for Falcons players this game, looking at profitable historical betting trends:

Best Falcons Player Prop Bets Today

Bijan Robinson has hit the Rushing Yards Over in 11 of his last 16 games (+5.10 Units / 27% ROI)
Bijan Robinson has hit the Longest Reception Over in his last 5 games (+5.00 Units / 85% ROI)
Tyler Allgeier has hit the Receptions Under in 5 of his last 7 games (+4.45 Units / 55% ROI)
Ray-Ray McCloud has hit the Receptions Under in 10 of his last 15 games (+4.00 Units / 20% ROI)
Tyler Allgeier has hit the Carries Over in 10 of his last 15 games (+3.95 Units / 22% ROI)

And here are some top NFL player prop bets for 49ers players for this matchup, looking at profitable historical betting trends:

Best 49ers Player Prop Best Bets Today

Christian McCaffrey has hit the Rushing Yards Under in 9 of his last 10 games (+7.85 Units / 69% ROI)
Demarcus Robinson has hit the Receptions Under in his last 7 games at home (+7.15 Units / 70% ROI)
Brian Robinson has hit the Receptions Under in 11 of his last 15 games (+6.80 Units / 35% ROI)
Christian McCaffrey has hit the Longest Rush Under in his last 6 games (+6.00 Units / 85% ROI)
Christian McCaffrey has hit the Receiving Yards Over in 8 of his last 10 games (+5.60 Units / 48% ROI)

Falcons Best Bets:

The Atlanta Falcons have hit the 4Q Game Total Under in 12 of their last 16 games (+7.60 Units / 41% ROI)
The Atlanta Falcons have covered the 1Q Spread in 11 of their last 18 games (+3.15 Units / 14% ROI)
The Atlanta Falcons have hit the 1Q Moneyline in 7 of their last 16 games (+2.85 Units / 12% ROI)
The Atlanta Falcons have covered the 1H Spread in 11 of their last 18 games (+2.65 Units / 13% ROI)
The Atlanta Falcons have hit the 1H Team Total Under in 5 of their last 8 away games (+1.95 Units / 23% ROI)

49ers Best Bets:

The San Francisco 49ers have covered the 1Q Spread in 15 of their last 20 games (+9.45 Units / 41% ROI)
The San Francisco 49ers have hit the 1Q Moneyline in 11 of their last 19 games (+7.85 Units / 33% ROI)
The San Francisco 49ers have hit the 2H Game Total Over in 11 of their last 16 games (+5.43 Units / 31% ROI)
The San Francisco 49ers have hit the Game Total Over in 13 of their last 20 games (+5.30 Units / 24% ROI)
The San Francisco 49ers have hit the 4Q Game Total Over in 11 of their last 17 games (+5.10 Units / 27% ROI)

Falcons Against the Spread (ATS) Record

Against the spread this NFL season, the Falcons are 3-2 (+0.8 Units / 14.41% ROI).

Falcons are 3-2 when betting on the Moneyline for +0.8 Units / 11.59% ROI
Falcons are 1-4 when betting the Over for -3.4 Units / -61.82% ROI
Falcons are 4-1 when betting the Under for +2.9 Units / ROI

49ers Against the Spread (ATS) Record

Against the spread this NFL season, the 49ers are 3-3 (-0.3 Units / -4.55% ROI).

49ers are 4-2 when betting on the Moneyline for +3.95 Units / 50.64% ROI
49ers are 4-2 when betting the Over for +1.8 Units / 27.27% ROI
49ers are 2-4 when betting the Under for -2.4 Units / -36.36% ROI

Atlanta Falcons: Keys to the Game vs. the San Francisco 49ers

The Falcons have gone three and out on 12% of their drives since the 2024 season — best in NFL; League Avg: 21%.

The Falcons have averaged 9.0 yards per play on first drive of the game this season — best in NFL; League Avg: 5.8.

The Falcons have thrown the ball 5% of the time (1 Pass Attempts/19 plays) on plays under center this season — lowest in NFL; League Avg: 28%.

The Falcons have gone three and out on 9% of their drives in the 1st half since the 2024 season — best in NFL; League Avg: 22%.

San Francisco 49ers: Keys to the Game vs. the Atlanta Falcons

The 49ers have targeted RBs 27% of the time (66 Pass Attempts/241 plays) this season — highest in NFL; League Avg: 18%.

The 49ers have 31 of 121 (26%) first downs have come on the ground (26%) this season — lowest in NFL; League Avg: 38%.

The 49ers have run successful plays on 14% of plays against a heavy rush this season — worst in NFL; League Avg: 46%.

The 49ers have gone three and out on 14% of their drives since the 2024 season — 2nd-best in NFL; League Avg: 21%.

Additional Matchup Notes for Atlanta Falcons vs. San Francisco 49ers