NFL Week 1 Odds for 2026 Season

Seattle Seahawks wide receiver Jaxon Smith-Njigba catches a touchdown pass on a 61-yard pass play during the first half of an NFL football game against the Jacksonville Jaguars, Sunday, Oct. 12 2025, in Jacksonville, Fla.
(AP Photo/Phelan M. Ebenhack)
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Below, bettors can find NFL odds for Week 1 of the 2026 regular season.

The new season begins in Seattle with a Super Bowl 60 rematch: Seahawks vs Patriots. Other standalone games include Rams vs 49ers, Giants vs Cowboys and Chiefs vs Broncos.

Notable Sunday contests include Bills at Texans and Commanders at Eagles.

NFL Odds Week 1: 2026 Season

Seahawks vs Patriots

Rams vs 49ers

Panthers vs Bears

Jaguars vs Browns

Bengals vs Buccaneers

Colts vs Ravens

Steelers vs Falcons

Texans vs Bills

Titans vs Jets

Lions vs Saints

Chargers vs Cardinals

Raiders vs Dolphins

Eagles vs Commanders

Vikings vs Packers

Giants vs Cowboys

Chiefs vs Broncos

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About the Author Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.